[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mild-or-moderate-asthma-with-allergic-sensitization\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mild-or-moderate-asthma-with-allergic-sensitization":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":5},"100374857","phase-2-5htp-regulation-of-asthma-in-children-100374857",false,"NCT04160910","5HTP Regulation Of Asthma In Children","Inclusion Criteria:\n\n* Age 8-18 Years of Age\n* Mild to Moderate Asthma based on ATS guidelines\n* Positive Allergy Test (positive skin or serum IgE)\n* Weight ≥ 70 lbs (32 kg)\n* CES-DC cut-off ≥ 15 (total score range is 0 to 60) or SCARED cut-off\n\n  * 25 (total score range is 0 to 142)\n* Ability to comply with study visits and study procedures\n* Informed Consent by participant and if applicable the parent or legal guardian\n\nExclusion Criteria:\n\n* Currently taking a SSRI\n* Taking a leukotriene inhibitor (montelukast, Zileuton)\n* Severe Asthma Based on ATS Guidelines\n* Taking a biologic medication (omalizumab, mepolizumab, benralizumab, dupilumab)\n* Medical History of Adverse Reaction to 5HTP\n* Physical findings that would compromise the safety of the study or the quality of the study data","ALL","8 Years","18 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","The purpose of this study is to learn more about if taking a supplement called 5-hydroxytryptophan (5HTP) can improve breathing and anxiety symptoms related to asthma. To help learn more subjects will either be assigned to a group that is taking the supplement (5HTP) or a group that is taking a placebo. This will be decided randomly. Later in the study subjects will crossover to the other group.There are 5 study visits over the course of about 12 weeks.",[26],"Mild or Moderate Asthma With Allergic Sensitization","RECRUITING","2026-09-28",{"date":30,"type":31},"2026-10-01","ACTUAL",{"date":33,"type":31},"2021-02-11",{"date":35,"type":20},"2026-12-31",{"name":37,"class":38},"Indiana University","OTHER"]