[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"molar-extraction-socket\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:molar-extraction-socket":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":35,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":5},"100648842","tissue-preservation-in-immediate-1c-implants-using-an-anatomical-prefabricated-healing-abutment-100648842",false,"NCT07727980","Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment","Aharct","Inclusion Criteria:\n\n* Willing to sign an IRB-approved informed consent and HIPAA authorization form prior to participation.\n* Between the ages of 20 and 75 years old.\n* ASA Classification I and II.\n* Hopeless maxillary or mandibular posterior teeth, eligible for immediate implantation, and with intact\u002Fsuccessfully restored adjacent teeth.\n* Willing to perform tasks associated with the study and to attend all study visits.\n\nExclusion Criteria:\n\n* HbA1c \\>6.5%) as per a chairside test (Siemens Bayer DCA 2000+);\n* smoker (any status);\n* immunodeficiency;\n* history of head and neck radiotherapy;\n* intake of bone anti-resorptive drugs;\n* cysts or tumors in the area;\n* self-reported pregnancy;\n* poor oral hygiene;\n* active periodontal disease;\n* acute endodontic infection and pus discharge on the site itself and adjacent areas;\n* lack of mutually protected occlusion;\n* insufficient inter-occlusal clearance (\\\u003C15 mm);\n* sites with an existing midfacial mucogingival recession\u002Fdeficiency (scar tissue);\n* sites with a high-scalloped, thin biotype.\n\nThose who appear to qualify will have a CBCT scan taken with an open bite and proper retractions of the cheek, lips, and tongue (standard of care), and the following inclusion criteria, based on the CBCT results, must be present in order for the subject to be fully enrolled in the study:\n\n* Sites with an intact or minimally damaged facial bone plate measuring greater than 1 mm in thickness;\n* Sites with at least 5 mm of healthy bone between the socket apex and the relevant anatomical structure (e.g., the maxillary sinus floor in the maxilla or the inferior alveolar nerve, submandibular\u002Fsublingual fossa, mental foramen, or anterior loop of the inferior alveolar nerve in the mandible);\n* In multirooted molar sockets, the presence of a short root trunk and an interradicular septum with a minimum height of 5 mm and a thickness of 3 mm.","ALL","20 Years","75 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to evaluate whether an anatomical prefabricated healing abutment (AHA) improves tissue preservation and clinical outcomes following immediate implant placement after tooth extraction in adults. Although immediate implant placement is a well-established treatment for replacing missing teeth, healing can result in changes to the surrounding bone and soft tissues that may affect the esthetic appearance, function, and long-term stability of the implant-supported restoration. This study will compare an anatomical healing abutment, designed to mimic the natural tooth emergence profile and support peri-implant tissues during healing, with a conventional healing abutment. The primary objectives are to determine whether the AHA better preserves soft tissue contours and alveolar bone, improves implant positioning accuracy and tissue stability during healing, and differs from a conventional healing abutment in complications or adverse events. Eligible participants will be adults requiring extraction of a hopeless tooth in the posterior maxilla or mandible who are suitable candidates for immediate implant placement. Following tooth extraction and implant placement, participants will receive either an anatomical prefabricated healing abutment or a conventional healing abutment and will return for scheduled follow-up visits over approximately 12 months to assess healing, implant stability, and changes in the surrounding hard and soft tissues. Researchers will collect clinical measurements, digital intraoral scans, photographs, and radiographic images throughout the study. Additional research imaging will be used to generate three-dimensional models to measure tissue volume changes and implant position accuracy. Specialized software will compare changes between the two groups over time. Safety will be evaluated by monitoring participants for complications, discomfort, inflammation, implant-related problems, and other adverse events throughout follow-up. All procedures will be performed by trained dental professionals using established clinical protocols. The results may improve understanding of how healing abutment design influences tissue preservation after immediate implant placement and help optimize future implant therapy by supporting better functional, esthetic, and long-term outcomes.",[27,28,29,30,31,32,33,34],"Tooth Loss","Dental Implant","Clinical Trials","Randomized Controlled Trial","Immediate Dental Implant Placement","Molar Extraction Socket","Maxilla","MANDIBLE",[36,37,38,39,40,41],"3-dimensional imaging","wound healing","healing abutments","immediate implant placement","soft tissue dimensional alterations","implant position accuracy","NOT_YET_RECRUITING","2026-07-24",{"date":45,"type":46},"2026-07-27","ACTUAL",{"date":48,"type":21},"2026-09",{"date":50,"type":21},"2028-09",{"name":52,"class":53},"University of Illinois at Chicago","OTHER",{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":16,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":65,"briefSummary":66,"conditions":67,"keywords":73,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":90,"locationsCount":92},"100601274","osseodensification-efficacy-on-molar-septum-expansion-in-immediate-molar-implant-placement-100601274","NCT07108361","\"Osseodensification Efficacy on Molar Septum Expansion in Immediate Molar Implant Placement","\"Osseodensification Efficacy on Molar Septum Expansion in Immediate Molar Implant Placement: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients requiring placement in the posterior region.\n\n  * ASA I and II patients who can undergo immediate implant placement and restorative procedures.\n  * Both males and females.\n  * Patient's age: 18-50 years old.\n  * Patients who can come for the follow-up visit.\n  * Patients who provide written informed consent\n\nExclusion Criteria:\n\n* Pregnancy.\n\n  * Smoking\n  * Patients with previously failed dental implants at the implant placement site.\n  * Patients with active infections.\n  * Other medical conditions that might affect the osseointegration of dental implants, such as diabetes, cardiovascular disease, hypertension, and osteoporosis","18 Years","50 Years",{"count":64,"type":21},80,[24],"The ideal positioning of immediate implants in molar extraction sockets often requires the osteotomy to be in the interradicular septum, which can be challenging in some cases, with traditional site preparation techniques. Also, the alveolar ridge undergoes various remodeling processes following tooth extraction, resulting in hard and soft tissue loss which complicates prosthodontic rehabilitation. Immediate implant placement help preserve the alveolar ridge dimensions and buccal ridge contour. While osseodensification has shown promise in enhancing primary stability and bone microarchitecture, its clinical and microstructural effects in molar extraction sockets remain underexplored. Although there is ample documentation of information on the temperature that is generated during preparation of implant sites, there are no studies available in the literature comparing conventional drilling and osseodensification techniques; therefore, the present investigation was aimed at analyzing the efficacy of osseodensification compared to conventional drilling in terms of bone dimensions preservation , changes in bone architecture during implant site preparation and heat generation to define which technique can be safely applied to achieve the necessary implant primary stability without damaging the surrounding bone.\n\nAim of the study:\n\nIs to compare the molar septum dimensions using osseodensification expansion versus the conventional drilling protocol and to assess the role of jumping gap grafting in preservation of the alveolar ridge dimensions and buccal ridge contour in addition to Evaluation of the effect of osseodensification on the bony micro-architecture and heat generation",[68,69,70,71,32,72],"Implant Osseointegration","Implant Osteotomy","Implant Placement","Implant Primary Stability","Immediate Implant Placement",[74,75,76,77,78,79,80,81,82,83],"non restorable tooth","molar extraction","multirooted teeth","extraction socket","immediate Implant placement","Osseodensification","ex-vivo","RCT","Jumping gap","Grafting","2025-08-06",{"date":86,"type":46},"2025-08-11",{"date":88,"type":21},"2025-09",{"date":50,"type":21},{"name":91,"class":53},"Ain Shams University",1]