[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"motor-imagery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:motor-imagery":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,43,80,107,132,154],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100607803","mental-imagery-on-upper-extremity-skills-100607803",false,"NCT07193303","Mental Imagery on Upper Extremity Skills","The Immediate Effect of Mental Imagery on Upper Extremity Skills With the Patients of Parkinson's Disease","Inclusion Criteria:\n\n* Healthy individuals aged 40-75 years, diagnosed with idiopathic PD according to the UK Parkinson's Disease Association Brain Bank criteria by a specialist neurologist, with a Modified Hoehn \\& Yahr (m-HY) scale stage ≤4, and with a Mini Mental State Examination score of ≥24 for those with training and ≥18 for those without training, and with no known disease, volunteered to participate in the study.\n* PD individuals with no other known neurological and\u002For systemic disease\n* PD individuals without any upper extremity contractures\n\nExclusion Criteria:\n\n* Individuals with diagnosed and\u002For treated psychiatric illnesses who are considered unable to complete the tests.\n* Individuals who is taking neuroleptic medications or antidepressants.\n* Individuals with orthopedic conditions that interfere with manual dexterity tests, such as severe dyskinesia, carpal tunnel syndrome, tendon injuries, or finger amputations; rheumatological conditions such as rheumatoid arthritis and osteoarthritis; and individuals with any neurological condition other than PD.","ALL","40 Years","75 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","Parkinson's disease (PD) is the second most common neurodegenerative disease, characterized pathologically by the progressive loss of dopaminergic neurons in the substantia nigra and clinically by the presence of motor symptoms such as bradykinesia, resting tremor, and\u002For rigidity. Among the motor deficits frequently observed in PD, patients are known to frequently report difficulties with manual dexterity. Many upper extremity and manual dexterity deficits are present in PD. Motor imagery (MI) is the imaginal execution of motor activities or the activation of specific muscles in the absence of any explicit feedback. This area of rehabilitation has been shown to be effective in improving and developing motor skills in many neurological conditions where patients exhibit motor recognition and execution impairments. MI can be applied at all stages of recovery from PD, is highly effective in movement-related pathologies, and can be performed independently.There is sufficient evidence that MI improves motor performance and learning in individuals with neurological disorders such as multiple sclerosis, stroke, and spinal cord injury. The study was designed to investigate the immediate effects of mental imagery, which is thought to be effective in controlling difficulties in planning and initiating movements in PD, on upper extremity skills. Therefore, the aim of this study was to determine the effect of mental imagery on upper extremity skills in PD.",[27,28,29],"PARKINSON DISEASE (Disorder)","Mental Imagery","Motor Imagery","RECRUITING","2026-07-12",{"date":33,"type":34},"2026-07-14","ACTUAL",{"date":36,"type":34},"2026-05-15",{"date":38,"type":21},"2027-01-30",{"name":40,"class":41},"Kahramanmaras Sutcu Imam University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":16,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":42},"100621328","immersive-aot-multisensory-stimulation-and-neurophysiological-correlates-in-children-with-cerebral-palsy-and-typical-development---a-pilot-study-100621328","NCT07369193","Immersive AOT: Multisensory Stimulation and Neurophysiological Correlates in Children With Cerebral Palsy and Typical Development - A Pilot Study","Immersive AOT: Multisensory Stimulation and Neurophysiological Correlates - A Pilot Study","ImmersiveAOT","Study Group: Inclusion Criteria:\n\n* Confirmed diagnosis of cerebral palsy, documented by clinical history and instrumental examinations;\n* Age between 7 and 25 years at the time of recruitment;\n* At least one verbal or nonverbal intellectual functioning index \\>= 70, to ensure understanding and compliance with the tasks required.\n\nExclusion Criteria:\n\n* Severe sensory disorders that compromise the feasibility of the study;\n* Neuropsychiatric comorbidity that precludes participation in the study.\n\nControl group: Inclusion Criteria\n\n* Age between 7 and 25 years at the time of recruitment;\n* Absence of intellectual disability, assessed through age-appropriate versions of the Raven's Progressive Matrices (Coloured Progressive Matrices for children up to 11 years; Standard Progressive Matrices for participants aged 12 years and older), yielding scores within the normative range and used to estimate non-verbal fluid intelligence;\n* Age-appropriate academic performance with no reports of significant learning difficulties, as verified through parental interview;\n* Absence of known neurological or psychiatric disorders, confirmed through parental interview;\n* Absence of motor impairments, defined as scoring above the 25th percentile on the Movement Assessment Battery for Children, Second Edition (MABC-2).",true,"7 Years","25 Years",{"count":55,"type":21},40,"OBSERVATIONAL","The discovery of the Mirror Neuron System (MNS) has promoted the development of rehabilitation techniques such as Action Observation Treatment (AOT) and Motor Imagery (MI). These are based on the principle that neural circuits active during execution, also activate during the observation or imagination of movements. These techniques have been found to be effective in several clinical populations including children with Cerebral Palsy (CP), the most common childhood-onset motor disorder. We hypothesize that a multimodal version of AOT, integrating not only visual stimuli (standard practice) but also auditory and tactile stimuli, could further enhance the activation of the MNS. In fact, everyday actions naturally involve multiple sensory channels, and evidence indicate that audio-visual action observation activates the MNS more intensely than visual stimuli alone, thus offering a potential improvement for CP rehabilitation.\n\nThe primary aim of this observational pilot study, conducted at IRCCS Fondazione Stella Maris, is to verify whether a multisensory (=immersive) AO session - combining visual, auditory, and tactile stimuli - produces greater activation of the MNS, than a traditional session (visual AO alone). Neural correlates will be measured through high-density Electroencephalography (hdEEG), with a specific focus on the modulation of the sensorimotor mu rhythm. Twenty children and adolescents with CP, aged 7-25 years, and 20 typically developing (TD) aged-matched peers will be recruited in the study. The study also aims to assess the level of participants' attention during stimuli presentation through eye tracking, and to verify whether immersive AO can influence MI abilities, measured through specific tasks and questionnaires (i.e., Motor Imagery Questionnaire for Children (MIQ-C, aged 7-12) and the Motor Imagery Questionnaire - 3 (MIQ-3) for adolescent). In an initial phase of the study both questionnaires will be the validated in a separate sample of 120 TD Italian children and 120 Italian adolescents or adults. The absence of intellectual disability will be assessed using the age-appropriate version of Raven's Progressive Matrices test.\n\nEach participant will undergo two EEG sessions: the immersive session will consist of watching first-person videos accompanied by auditory stimuli consistent with the action and tactile stimuli provided by TouchDIVER Pro haptic gloves (Weart, CE-marked device), suitably adapted for the paediatric population. The traditional session will consist of watching videos without sounds or any tactile additional stimulus. The two sessions will be performed in a in random order. In both sessions, after the observation phase, participants will be asked to perform or imagine the same actions presented in the videos. During observation, eye movements and gaze behavior will be monitored using an eye tracking system. Throughout each session, cortical activity will be recorded using a 128-channel hdEEG net. The sessions will be video-recorded to accurately monitor participants motor behavior, response times, and compliance with the protocol.\n\nAt the end of each EEG session, participants will be administered the MIQ-C or MIQ-3 questionnaire and a short task to assess MI abilities. In this task, participants will watch some of the videos previously used during the EEG session and will then be asked to imagine the same action. In this case, their imagery will be interrupted at specific time points, and they will be asked to select, from two images, the moment of the action corresponding to the point at which they were interrupted.\n\nData analysis will examine within- and between-groups differences for the immersive AO vs the traditional AO. Correlation analysis will be also performed between neurophysiological data, attentional data, questionnaires, MI responses and standardized clinical assessments ( for the CP group), in order to understand how the participants' motor and cognitive abilities influence the activation of the circuits involved in the experimental tasks.",[59,60,29,61],"Cerebral Palsy (CP)","CP (Cerebral Palsy)","Action Observation",[63,64,65,29,66,67,68,69,70],"Immersive","AOT","Cerebral Palsy","haptic gloves","eye-tracker","Mirror Neuron System","EEG","multisensory","2026-04-01",{"date":73,"type":34},"2026-04-02",{"date":75,"type":34},"2026-01-19",{"date":77,"type":21},"2027-06",{"name":79,"class":41},"IRCCS Fondazione Stella Maris",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":18,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":90,"briefSummary":91,"conditions":92,"keywords":95,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":42},"100601097","near-infrared-imaging-of-motor-imagery-effects-in-spinal-cord-injury-100601097","NCT07106060","Near-Infrared Imaging of Motor Imagery Effects in Spinal Cord Injury","A Near-Infrared Functional Imaging Study on Motor Imagery Training in Patients With Spinal Cord Injury","Inclusion Criteria:\n\n1. The vital signs are stable and the spine is stable, making the subject suitable for exercise testing.\n2. Patients with spinal cord injury (SCI) who meet the international diagnostic criteria for SCI neurology revised by the American SCI Society in 2019 and have been diagnosed by CT or MRI.\n3. The injury level of SCI is C5-T12, and the ASIA grade is A-C.\n4. The course of the disease is ≤12 months (but the spinal shock period must have passed).\n5. Age: 18-75 years old, regardless of gender.\n6. Good cognitive function, able to understand and actively participate in the training program, and willing to sign the informed consent form for this clinical study.\n\nExclusion Criteria:\n\n1. Those with tumors, tuberculosis, hematologic diseases, or dysfunction of important organs such as the heart and liver;\n2. Those with unstable fractures;\n3. Those with severe abnormal limb muscle tone and joint contracture deformities;\n4. Those with severe pain that cannot tolerate activities;\n5. Those with severe emotional problems who cannot cooperate to complete the study.","18 Years",{"count":89,"type":21},36,[24],"The primary objective of this clinical trial is to investigate the efficacy of motor imagery-based brain-computer interface (MI-BCI) technology in improving motor function among patients with spinal cord injury (SCI), as well as its impact on cortical motor area function across varying states. To achieve this, the study will implement MI-BCI intervention in SCI patients, evaluate post-treatment motor function improvements, and assess changes in cortical motor area oxygen metabolism (via functional near-infrared spectroscopy, fNIRS) and neural activity (via electroencephalography, EEG). The ultimate goal is to establish a novel rehabilitation strategy for SCI.\n\nSpecifically, the trial aims to: (1) determine whether MI-BCI effectively enhances motor function in SCI patients; and (2) clarify the differential effects of MI-BCI on cortical motor area function under distinct states (e.g., resting vs. task-performing) in this population.\n\nParticipants will be randomly assigned to one of two groups: the experimental group will undergo MI-BCI training, while the control group will receive active cycling training (as a conventional rehabilitation control). Both interventions will be structured as 20-minute sessions, administered 5 days per week, over a total of 4 weeks.Pre- and post-treatment assessments will include: lower limb motor function (measured by the Lower Limb Motor Score), activities of daily living (evaluated via the Modified Barthel Index), walking capacity (quantified using the Spinal Cord Injury Walking Index), and cortical motor activity (captured through fNIRS and EEG measurements).",[93,29,94],"SCI - Spinal Cord Injury","Brain-Computer Interfaces",[93,96,94,97],"motor imagery","Functional near-infrared spectroscopy","2025-07-30",{"date":100,"type":34},"2025-08-06",{"date":102,"type":34},"2025-01-01",{"date":104,"type":21},"2026-02-01",{"name":106,"class":41},"Shengjing Hospital",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":16,"minAge":87,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":42},"100588798","the-effect-of-upper-extremity-motor-function-trunk-control-and-motor-imagery-ability-on-turkish-language-skills-in-individuals-with-stroke-100588798","NCT06946082","The Effect of Upper Extremity Motor Function, Trunk Control and Motor Imagery Ability on Turkish Language Skills in Individuals With Stroke","It is to Examine the Relationship Between Upper Extremity Motor Function, Trunk Control, Motor Imagery.","Inclusion Criteria:\n\n* 18 years of age or older\n* Stroke onset more than 1 week\n* Not having practiced imagery before\n* Being a native speaker of Turkish\n* Standardized Mini Mental Test (SMMT) Score of 24 and above\n* History of cerebrovascular events\n* Not having any neurological disorder other than stroke\n* The ability to grasp and hold a 2.5 cm cube\n\nExclusion Criteria:\n\n* No consent from the family or person\n* Having had a stroke before\n* Severe hearing or vision loss\n* Individuals are excluded if they have other primary medical conditions that may affect language and motor functions (e.g. brain tumor, Parkinson's disease, severe post-stroke depression, Alzheimer's disease) or have undergone surgery.",{"count":115,"type":21},101,"A large number of people have a stroke each year and it is a major cause of disability worldwide. Upper limb motor impairments, aphasia, body control problems and decreased motor imagery ability are common after stroke. Although there are studies showing that these impairments may be related to each other, there is no comprehensive study examining the relationship between Turkish language skills and these motor functions. The aim of this study was to evaluate the relationship between Turkish language skills and upper extremity motor function, trunk control and motor imagery ability in stroke patients.",[118,119,120,121,122,29],"Hemiplegia","Aphasia","Stroke","Trunk","Upper Limbs","2025-04-19",{"date":125,"type":34},"2025-04-27",{"date":127,"type":34},"2024-12-10",{"date":129,"type":21},"2025-12-10",{"name":131,"class":41},"Izmir Bakircay University",{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":16,"minAge":138,"maxAge":139,"enrollmentInfo":140,"targetDuration":4,"studyType":22,"phases":141,"briefSummary":142,"conditions":143,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":42},"100568062","effect-of-multisensory-motor-imagery-training-on-muscle-performance-and-coordination-in-children-with-spastic-diplegia-100568062","NCT06676332","Effect of Multisensory Motor Imagery Training on Muscle Performance and Coordination in Children With Spastic Diplegia","Inclusion Criteria:\n\n* Their age will be ranged from 8-12 years.\n* Mild degree of spasticity ranged from 1 to 1+ according to Modified Ashworth Scale\n* Their motor function will be at level I and II according to Gross Motor Function Classification System GMFCS\n* They will be able to follow instructions during evaluation and treatment.\n\nExclusion Criteria:\n\n* \\- Cardiovascular or respiratory disorders.\n* Botulinium muscular injection in the last 6 months\n* Surgical interference in lower limbs and\u002For spine.\n* Muscloskeletal problems or fixed deformities in the spine and\u002For lower extremities.\n* Seizures.\n* Visual or hearing impairment","8 Years","12 Years",{"count":20,"type":21},[24],"PURPOSE:\n\nThe current study aims to:\n\n* Determine the effect of multisensory motor imagery training on muscle performance including (peak torque, work, power) of trunk and knee flexors and extensors in children with spastic diplegia.\n* Determine the effect of multisensory motor imagery training on coordination, strength and agility in children with spastic diplegia.\n\nBACKGROUND: Multisensory motor imagery training has an effect on muscle performance and coordination in children with spastic diplegia\n\nHYPOTHESES: There will be no effect of multisensory motor imagery training on muscle performance, coordination and strength and agility in children with spastic diplegic CP.\n\nRESEARCH QUESTION: Is there an effect of multisensory motor imagery training on coordination, strength and agility in children with spastic diplegia?",[144,29],"Spastic Diplegia","2025-02-15",{"date":147,"type":34},"2025-02-18",{"date":149,"type":34},"2024-11-16",{"date":151,"type":21},"2025-05",{"name":153,"class":41},"Cairo University",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":4,"eligibilityCriteria":160,"healthyVolunteers":51,"sex":16,"minAge":87,"maxAge":4,"enrollmentInfo":161,"targetDuration":4,"studyType":22,"phases":163,"briefSummary":164,"conditions":165,"keywords":4,"overallStatus":169,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":42},"100570498","evaluation-of-a-home-based-aomi-intervention-on-cognitive-function-and-depression-among-adults-with-sci-100570498","NCT06708026","Evaluation of a Home-based AOMI Intervention on Cognitive Function and Depression Among Adults with SCI","Evaluation of a Home-based Action Observation and Motor Imagery Intervention on Cognitive Function and Depression Among Adults with Spinal Cord Injury: a Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of SCI according to the International Standards for the Neurological Classification of SCI with confirmation by computed tomography\u002Fmagnetic resonance imaging;\n* At least 18 years old;\n* With stable spinal systems and good vital signs, and currently living in the community and having SCI for more than 6 months;\n* No contraindications to undergoing MRI examination (e.g., no metal or electronic devices in the body, not pregnant, and absence of claustrophobia);\n* Having a mobile Internet terminal (usually a smartphone) and proficient independent or caregiver-assisted usage;\n* Able to communicate in Cantonese and to provide informed consent.\n\nExclusion Criteria:\n\n* Having severe problems in hearing, verbal communication, or vision;\n* Engaged in ongoing psychotherapy or any other physiotherapy\u002F exercise\u002F relaxation interventions;\n* Physically active for more than 150 minutes moderate-intensity exercise per week;\n* Diagnosis of mental disorders or substance misuse;\n* With severe cognitive impairment (Hong Kong Montreal Cognitive Assessment (HK-MoCA) score ≤ 18.",{"count":162,"type":21},46,[24],"The investigators propose a pilot randomized clinical trial to determine if adults with spinal cord injury (SCI) show improved cognitive function and depression following home-based Action Observation and Motor Imagery (AOMI) training. It is hypothesized that the home-based AOMI intervention will show satisfactory feasibility and acceptability. They also hypothesize that AOMI training can be used as a rehabilitative tool for improving cognitive function and depression in adults with SCI, because it engages and strengthens similar neural systems as actual exercise.",[166,167,29,168],"Spinal Cord Injuries (SCI)","Depression","Cognitive Functions","NOT_YET_RECRUITING","2025-02-03",{"date":172,"type":34},"2025-02-06",{"date":174,"type":21},"2025-03-01",{"date":176,"type":21},"2026-06-30",{"name":178,"class":41},"The Hong Kong Polytechnic University"]