[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"muscle-function-handgrip-strength-test\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:muscle-function-handgrip-strength-test":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100647585","effects-of-policosanol-and-exercise-on-fitness-and-lipids-in-people-with-elevated-blood-lipids-100647585",false,"NCT07710261","Effects of Policosanol and Exercise on Fitness and Lipids in People With Elevated Blood Lipids","Effect of Policosanol Supplementation Combined With Concurrent Exercise Training on Physical Fitness and Lipid Profiles in Healthy Volunteers With Elevated Blood Lipid But Not Required Medical Treatment","Inclusion Criteria:\n\n* Men and women aged 25 to 59 years.\n* BMI between 18.5 and 29.9 kg\u002Fm².\n* Diagnosed with or presenting with dyslipidemia within the past 3 months, based on laboratory assessment at baseline or a standard laboratory report issued within the past 3 months, according to the National Cholesterol Education Program Adult Treatment Panel III criteria, defined by at least one of the following:\n* Total cholesterol ≥ 200 mg\u002FdL;\n* Low-density lipoprotein cholesterol ≥ 130 mg\u002FdL and \\\u003C 190 mg\u002FdL;\n* High-density lipoprotein cholesterol \\\u003C 40 mg\u002FdL in men;\n* High-density lipoprotein cholesterol \\\u003C 50 mg\u002FdL in women;\n* Triglycerides ≥ 150 mg\u002FdL.\n* Free from chronic or comorbid conditions that contraindicate participation in aerobic or resistance exercise.\n* Cleared for physical activity based on the Physical Activity Readiness Questionnaire for Everyone.\n* Not regularly physically active during the preceding 3 months, defined as fewer than 3 exercise sessions per week or less than 150 minutes of exercise per week.\n* Able and willing to participate in the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Current or recent use within the past 3 months of lipid-lowering medications or dietary supplements known to influence lipid metabolism, including statins, fibrates, niacin, omega-3 fatty acids, red yeast rice, or policosanol.\n* Known allergy or hypersensitivity to policosanol, sugarcane derivatives, capsule components, or any excipients in the supplement formulation.\n* Presence of chronic or comorbid conditions that may make exercise participation unsafe, including but not limited to cardiovascular disease, chronic obstructive pulmonary disease, severe arthritis, osteoporosis, uncontrolled diabetes, gastrointestinal disorders, or neurological impairments affecting movement control.\n* High-risk lifestyle factors, including heavy smoking, excessive alcohol consumption, or use of recreational drugs.\n\nInability to comply with the study protocol, including inability to participate in the exercise program when assigned or inability to attend scheduled follow-up assessments.\n\n\\- Refusal or inability to provide written informed consent independently.","ALL","25 Years","59 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will evaluate the effects of policosanol supplementation, concurrent exercise training, and their combination on physical fitness, muscle recovery, inflammatory markers, and blood lipid profiles in adults with elevated blood lipids who are not currently indicated for lipid-lowering medication.\n\nParticipants will be randomly assigned to one of four groups for 12 weeks: policosanol plus exercise training, policosanol alone, placebo plus exercise training, or placebo without structured exercise training. Participants assigned to the supplementation groups will take policosanol 5 mg per day, while those assigned to the placebo groups will take a matching placebo. Participants assigned to the exercise groups will complete a standardized concurrent exercise training program combining aerobic and resistance exercise.\n\nThe study will compare changes in physical fitness, lipid profiles, and selected blood biomarkers before and after the intervention. The findings may help determine whether low-dose policosanol, alone or combined with exercise training, can support cardiometabolic health and physical fitness in adults with dyslipidemia.",[27,28,29,30,31],"Dyslipidemia","Elevated Blood Lipids","Physical Fitness","Exercise Training","Muscle Function, Handgrip Strength Test",[33,34,35,36,37,38,39,40,29,27,41],"Policosanol","Octacosanol","Dietary Supplement","Concurrent Exercise Training","Aerobic Exercise","Resistance Exercise","Blood Lipid Profile","Muscle Function","Nutraceutical","NOT_YET_RECRUITING","2026-07-15",{"date":45,"type":46},"2026-07-17","ACTUAL",{"date":48,"type":21},"2026-06-22",{"date":50,"type":21},"2027-01-29",{"name":52,"class":53},"Mahidol University","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":16,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":66,"phases":4,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":83,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":54},"100568382","the-role-of-nutrition-in-muscle-function-of-bariatric-surgery-patients-100568382","NCT06680492","The Role of Nutrition in Muscle Function of Bariatric Surgery Patients","Inclusion Criteria:\n\n* Male and female\n* Aged 18 to 65 years old\n* Undergoing first bariatric surgery (any type)\n* Diabetics and non-diabetics\n* Non-smokers and non-cannabis consumers\n\nExclusion Criteria:\n\n* Pregnant and breastfeeding women\n* Individuals undergoing second bariatric surgery\n* Regular smokers and cannabis consumers\n* Current use of Ozempic (or Ozempic-like medication) and anti-psychotic meds\n* Limited physical mobility (using walking aids such as canes, walkers, or wheelchairs) and issues with hand resistance\n* Kidney disease, non-controlled \u002F unstable hypertension and hypothyroidism, and any metabolic disease other than diabetes",true,"18 Years","65 Years",{"count":65,"type":21},75,"OBSERVATIONAL","Current recommendations for protein intake after bariatric surgery are not based on strong scientific evidence. It remains unclear how much protein should be eaten to minimize muscle loss and preserve the metabolism and function of individuals post-bariatric surgery.\n\nThe objective of this study is to analyze the relationships between changes in body composition, nutrition and protein intake, and muscle function after bariatric surgery to further our understanding of the nutritional needs of patients after bariatric surgery.\n\nWe intend to recruit around 75 participants, men and women, aged between 18 and 65 years. Participants will be recruited from the Bariatric Surgery Clinic, McGill University Health Center.",[69,70,31,71,72],"Obesity, Diabetes, Nutrition, Physical Health","Body Composition Changes","Protein Metabolism","Bariatric Surgery Patients",[74,75,76,77,78,79,80,81,82],"Obesity","Bariatric sugery","Protein function","Muscle function","6-Minute Walk Test","Handgrip Strength Test","Nutritional needs","Nutritional guides","Nutrition","RECRUITING","2024-11-06",{"date":86,"type":46},"2024-11-08",{"date":88,"type":46},"2017-06-23",{"date":90,"type":21},"2026-01",{"name":92,"class":53},"Concordia University, Montreal"]