[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"muscle-strength-dynamometer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:muscle-strength-dynamometer":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100658083","acute-mental-fatigue-and-muscle-strength-100658083",false,"NCT07846618","Acute Mental Fatigue and Muscle Strength","Influence of Acute Mental Fatigue on Muscle Strength and Limb Symmetry in Healthy Adults","Inclusion Criteria:\n\n1. Age 18-39 years\n2. Able to produce maximal force against Biodex protocol\n3. Able to perform required lower extremity movements through range of motion necessary for Biodex protocol\n4. No known cognitive impairment\n5. Sufficient musculoskeletal health to complete the tasks\n\nExclusion Criteria:\n\n1. History of a neurological disorder, disease, or cognitive impairment that may affect cognition, motor control, reaction time, or force production\n2. History of musculoskeletal injury affecting the lower extremities within the past 6 months\n3. History of lower extremity surgery affecting force production of the hip, knee, or ankle\n4. Color-vision impairment\n5. Significant visual or hearing impairment\n6. History of migraine headaches\n7. Current significant sleep disturbances or sleep deprivation\n8. Head injury that may affect cognitive function\n9. Medical condition affecting ability to produce maximal force safely\n10. Allergy to adhesive tape, parabens, or propylene glycol\n11. Scalp lacerations, open wounds, or sutures on the scalp\n12. Cranial surgery or skull defects\n13. History of unexplained dizziness or fainting in the past 6 months\n14. Individuals who are pregnant, prisoners, or not yet adults\n15. Inability to communicate with investigators\n16. Inability to provide written informed consent",true,"ALL","18 Years","39 Years",{"count":21,"type":22},50,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will investigate the acute effects of mental fatigue on lower-extremity muscle strength and limb symmetry in healthy young adults. Participants will complete lower-extremity strength testing before and after a standardized computer-based mental fatigue protocol involving tasks of attention, reaction time, concentration, and working memory. Muscle strength and limb symmetry will be assessed using isokinetic dynamometry, with muscle activity measured using surface electromyography. Participants will also complete subjective measures of mental fatigue, sleepiness, mental effort, and perceived physical exertion. Heart rate will be monitored throughout the study, and brain activity may be assessed during cognitive tasks. The study will determine whether acute mental fatigue is associated with changes in muscle strength, limb symmetry, and neuromuscular performance.",[28,29],"Mental Fatigue","Muscle Strength Dynamometer",[31,32,33,34,35],"mental fatigue","muscle strength","limb symmetry","isokinetic dynamometry","electromyography","RECRUITING","2026-09-23",{"date":39,"type":40},"2026-09-29","ACTUAL",{"date":37,"type":40},{"date":43,"type":22},"2027-12-31",{"name":45,"class":46},"Florida Institute for Human and Machine Cognition","OTHER"]