[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"musical-performance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:musical-performance":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100656467","safety-and-acute-effects-of-tdcs-on-musical-performance-in-adolescent-musicians-100656467",false,"NCT07826923","Safety and Acute Effects of tDCS on Musical Performance in Adolescent Instrumentalists","Safety, Tolerability, and Acute Effects of Transcranial Direct Current Stimulation on Technical, Expressive, and Stage Aspects of Musical Performance in Instrumentalists Aged 12 to 16 Years: A Randomized Sham-Controlled Proof-of-Concept Study","Inclusion Criteria:\n\n* Age 12 to 16 years, inclusive, at the time of enrollment.\n* Regular participation in instrumental music training for at least 12 months.\n* Ability to safely perform a previously learned instrumental musical piece or excerpt lasting approximately 1 to 2 minutes.\n* General health status compatible with participation, confirmed through a pre-session safety screening.\n* No known neurological or clinical condition considered to increase the risk associated with stimulation.\n* No current use of medication or substances considered by the study team to substantially alter cortical excitability or increase procedural risk.\n* Written informed consent from a legal guardian.\n* Written assent from the adolescent and voluntary willingness to participate.\n\nExclusion Criteria:\n\n* History of epilepsy or non-febrile seizures.\n* Relevant brain injury, previous cranial surgery, or other neurological condition considered incompatible with the protocol.\n* Pacemaker, implanted electronic device, neurostimulator, or cranial metallic implant that could pose a risk or interfere with stimulation.\n* Current use of anticonvulsant medication or other medication considered by the study team to represent a contraindication or unacceptable precaution.\n* Previous experience with tDCS when such experience could compromise blinding.\n* Dermatitis, wounds, infection, burns, significant pain, or other scalp abnormalities at the planned electrode sites.\n* Known or suspected pregnancy, as a precaution; pregnancy testing will not be performed as part of the study.\n* Acute illness or relevant symptoms on the day of the session, including fever, significant headache, persistent dizziness, or relevant sleep deprivation, when these findings justify postponement or exclusion for safety reasons.",true,"ALL","12 Years","16 Years",{"count":21,"type":22},24,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized, sham-controlled proof-of-concept study aims to investigate the safety, tolerability, and acute effects of transcranial direct current stimulation (tDCS) on musical performance in adolescent instrumentalists aged 12 to 16 years. Twenty-four participants will be randomly assigned to active or sham tDCS. Active stimulation will consist of 2.0 mA anodal tDCS applied for 30 minutes using 5 × 7 cm electrodes positioned over FCz and Fp2. Participants will perform the same previously learned instrumental musical piece or excerpt before stimulation, immediately after stimulation, and two hours after stimulation. Musical performances will be evaluated by blinded expert raters using a standardized performance rubric. Safety and tolerability will be monitored using a structured symptom checklist and predefined stopping criteria. Self-rated performance, nervousness, confidence, blinding, and protocol feasibility will also be explored.",[28,29],"Musical Performance","Neuromodulation",[31,32,33,34,35,36,37],"Transcranial Direct Current Stimulation","Adolescent","Music Performance","Instrumental Musicians","Safety","Tolerability","Motor Performance","NOT_YET_RECRUITING","2026-09-30",{"date":41,"type":42},"2026-10-05","ACTUAL",{"date":44,"type":22},"2026-10-07",{"date":46,"type":22},"2026-12-31",{"name":48,"class":49},"Centro Universitário Augusto Motta","OTHER"]