[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"myofascial-pain-syndromes\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:myofascial-pain-syndromes":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,54,84,111,132],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100649056","treatment-of-pectoralis-trigger-points-in-patients-with-pseudo-angina-100649056",false,"NCT07728357","Treatment of Pectoralis Trigger Points in Patients With Pseudo Angina","Comparative Effects of Graston Technique Versus Local Ischemic Compression on Trigger Points of Pectoralis Major and Minor Among Pseudo-angina Patients","GT-LIC","Inclusion Criteria:\n\n* Participants which fulfill the Simon's Trigger Point Diagnostic Criteria\n* Referred by Cardiologist • Patients with Trigger Points in chest Muscles and left Pectoralis Major and Minor muscles.\n\nExclusion Criteria:\n\n* Spinal Deformity • Gastric Problems • Any cardiac disease • Heart Burns • Panic Attacks • Pleurisy • Pulmonary Embolism • Pericarditis.","ALL","25 Years","50 Years",{"count":21,"type":22},36,"ESTIMATED","INTERVENTIONAL",[25],"NA","Pseudo-angina is a musculoskeletal condition characterized by chest pain that resembles angina but occurs due to non-cardiac causes, particularly myofascial trigger points in the chest wall muscles. Trigger points in the pectoralis major and minor muscles may contribute to pain, discomfort, and functional limitations by affecting muscle activity and movement. Manual therapy techniques such as the Graston Technique and Local Ischemic Compression (LIC) are commonly used to manage soft tissue dysfunction and myofascial trigger points. This study aims to compare the effects of the Graston Technique and Local Ischemic Compression on pain reduction and functional improvement in patients with pseudo-angina.",[28,29,30,31],"Pseudo Angina","Myofascial Pain Syndromes","Pectoralis Muscles","Musculoskeletal Chest Pain",[33,34,35,36,37,38,39,40],"chest pain","Non-cardiac chest pain","Myofascial pain syndrome","Graston Technique","Instrument-assisted soft tissue mobilization","Chest wall pain","Musculoskeletal chest pain","Local Ischemic Compression","NOT_YET_RECRUITING","2026-07-22",{"date":44,"type":45},"2026-07-27","ACTUAL",{"date":47,"type":22},"2026-07-25",{"date":49,"type":22},"2026-11-01",{"name":51,"class":52},"University of Faisalabad","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":17,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":23,"phases":66,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":53},"100647134","comparative-analysis-of-dry-needling-techniques-for-orofacial-myofascial-pain-100647134","NCT07706153","Comparative Analysis of Dry Needling Techniques for Orofacial Myofascial Pain","Comparative Analysis of the Effectiveness and Comfort of Different Dry Needling Techniques in the Treatment of Orofacial Myofascial Pain: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Clinical diagnosis of Myofascial Pain (with or without referred pain) in the masseter and\u002For temporalis muscles according to the Diagnostic Criteria for Temporomandibular Disorders (DC\u002FTMD) Axis I\n* Presence of at least one active trigger point in a taut band reproducing the chief complaint\n* Baseline pain intensity ≥ 2 on the VAS in the last two weeks\n* Confirmed pressure pain threshold (PPT ≤ 1.5 kg\u002Fcm²)\n* Signed informed consent form\n\nExclusion Criteria:\n\n* TMD treatment in the last 3 months (physical therapy, needling, laser therapy) or Botulinum Toxin injection in the orofacial region within 12 months\n* Continuous systemic use of analgesics, anti-inflammatories, or muscle relaxants\n* Diagnosis of fibromyalgia, systemic rheumatic diseases, neurological disorders, or neuropathic pain\n* Needle phobia (belonephobia), coagulation disorders, or use of anticoagulant drugs\n* Active skin or odontogenic infections in the application area\n* History of recent facial trauma or orthognathic\u002Fjoint surgery\n* Pregnancy",true,"18 Years","80 Years",{"count":65,"type":22},45,[25],"This study aims to compare the clinical effectiveness and individual comfort of three distinct dry needling techniques (dynamic, static, and hybrid) for managing orofacial myofascial pain. Myofascial pain is a highly prevalent manifestation of temporomandibular disorders (TMD), characterized by painful trigger points in the masticatory muscles, such as the masseter and temporalis, which cause pain, muscle tenderness, and jaw movement limitations. While dry needling is widely recognized as an effective minimally invasive therapy to deactivate these trigger points, there is still a lack of consensus in scientific literature regarding the standardization of application protocols.\n\nTo address this gap, this randomized, triple-blind, parallel-group clinical trial will enroll 45 individuals diagnosed with myofascial pain according to the Diagnostic Criteria for Temporomandibular Disorders (DC\u002FTMD). Participants will be randomly allocated into three equal groups (15 individuals per group): Group 1 will receive dynamic dry needling (fanning technique); Group 2 will receive static dry needling (needle kept in situ for 10 minutes); and Group 3 will receive a hybrid approach (combining an initial static period followed by dynamic manipulation).\n\nThe primary outcome will evaluate changes in self-reported pain intensity using a Visual Analog Scale (VAS) from baseline to 7 days post-intervention. Secondary outcomes will assess changes in pressure pain thresholds (PPT) via digital algometry, mandibular range of motion via digital caliper measurements, and the subjective perception of comfort and acceptability of each technique. Evaluations will be conducted at baseline, immediately post-intervention, at 7 days, and at 15 days of follow-up. The findings are expected to contribute to the standardization of more effective and comfortable clinical protocols for managing orofacial pain.",[29,69,70],"Facial Pain","Trigger Points",[72,73,74],"dry needling","orofacial pain","myofascial pain syndromes","2026-07-21",{"date":77,"type":45},"2026-07-23",{"date":79,"type":22},"2026-08-01",{"date":81,"type":22},"2027-04-01",{"name":83,"class":52},"Flávio Magno Gonçalves",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":17,"minAge":62,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":93,"phases":4,"briefSummary":94,"conditions":95,"keywords":96,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":107,"leadSponsor":109,"locationsCount":53},"100646590","predictors-of-treatment-expectations-in-myofascial-pain-syndrome-100646590","NCT07689396","Predictors of Treatment Expectations in Myofascial Pain Syndrome","Determining the Predictors of Treatment Expectations in Individuals With Myofascial Pain Syndrome: A Cross-Sectional Study","Inclusion Criteria:\n\n* Age 18 years and older\n* Diagnosis of myofascial pain syndrome\n* Pain intensity of at least 3 on the Visual Analog Scale\n* Scheduled to receive at least two weeks of physiotherapy\n\nExclusion Criteria:\n\n* Diagnosed psychiatric disorder\n* Chronic systemic disease\n* Any barrier preventing communication",{"count":92,"type":22},85,"OBSERVATIONAL","This cross-sectional study aims to determine the predictors of treatment expectations in individuals with myofascial pain syndrome (MPS). MPS is one of the most common causes of musculoskeletal pain and is associated with reduced quality of life. Patients' pre-treatment expectations are known to influence clinical outcomes, yet the factors that predict these expectations have not been established. Adults diagnosed with MPS who are scheduled to receive physiotherapy complete measures of treatment expectations, pain intensity and duration, health-related quality of life, and fatigue. Multiple regression analysis is used to examine the extent to which pain intensity, pain duration, quality of life, and fatigue predict treatment expectations.",[29],[97,98,99,100,101],"pain","myofascial pain syndrome","treatment expectation","quality of life","fatigue","RECRUITING","2026-07-01",{"date":105,"type":45},"2026-07-08",{"date":103,"type":45},{"date":108,"type":22},"2026-09-01",{"name":110,"class":52},"KTO Karatay University",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":17,"minAge":62,"maxAge":18,"enrollmentInfo":117,"targetDuration":4,"studyType":23,"phases":119,"briefSummary":120,"conditions":121,"keywords":4,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":53},"100633379","immediate-effect-of-dry-needling-on-calf-muscles-pain-pressure-thresholdsprint-speed-and-functional-performance-in-amateur-football-player-100633379","NCT07525921","Immediate Effect of Dry Needling on Calf Muscles Pain Pressure Threshold,Sprint Speed and Functional Performance in Amateur Football Player","Inclusion Criteria:\n\n* Amateur football players aged 18-25 years.\n\nParticipation in club-level football for at least one year.\n\nPresence of active myofascial trigger point in gastrocnemius or soleus confirmed by palpation.\n\nWillingness to participate and provide informed consent.\n\nExclusion Criteria:\n\n* History of calf muscle tear, fracture, or lower limb surgery.\n\nCurrent use of muscle relaxants or anti-inflammatory medication.\n\nKnown bleeding disorders or anticoagulant therapy.\n\nLocal infection, skin lesion, or contraindication to dry needling.\n\nNeurological or vascular disorders affecting lower limb function.",{"count":118,"type":22},60,[25],"This randomised single-blind trial will evaluate the immediate effect of a single session of dry needling versus sham needling on calf muscle myofascial trigger points among amateur football players aged 18-25 years. Primary and secondary outcomes are Pressure Pain Threshold (algometer), Sprint Speed (shuttle run test), and Functional Performance (single-leg hop). Outcomes will be measured immediately pre- and post-intervention. Data analysis will be performed in SPSS version 27 using paired and independent t-tests (p \\\u003C 0.05).",[29,70,122],"Gastrocnemius Muscle","2026-04-06",{"date":125,"type":45},"2026-04-13",{"date":127,"type":45},"2025-08-29",{"date":129,"type":22},"2026-06-01",{"name":131,"class":52},"Foundation University Islamabad",{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":138,"eligibilityCriteria":139,"healthyVolunteers":11,"sex":17,"minAge":62,"maxAge":18,"enrollmentInfo":140,"targetDuration":4,"studyType":23,"phases":142,"briefSummary":143,"conditions":144,"keywords":147,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":4},"100602958","post-isometric-relaxation-in-temporomandibular-disorders-100602958","NCT07130279","Post-Isometric Relaxation in Temporomandibular Disorders","The Effect of Post-Isometric Relaxation Technique on Cervical Range of Motion, Mandibular Mobility, Head Anterior Tilt, and Kyphotic Posture in Individuals With Temporomandibular Joint Dysfunction","PIR-TMD","Inclusion Criteria:\n\n* Age between 18 and 25 years\n* Diagnosis of moderate or severe temporomandibular joint dysfunction (TMD) according to the Fonseca Anamnestic Questionnaire\n* Presence of TMD symptoms for at least 6 months\n* No TMD treatment received within the last 6 months\n* Presence of chewing muscle pain for at least 6 months\n* Able and willing to participate in the study and follow the exercise program\n* Signed informed consent form\n\nExclusion Criteria:\n\n* History of jaw or facial trauma within the past year\n* History of temporomandibular joint surgery\n* Presence of systemic rheumatologic, neurological, or musculoskeletal disorders affecting the jaw, neck, or spine\n* Pregnancy\n* Current participation in another clinical trial\n* Inability to perform the exercise program due to medical or physical limitations\n* Refusal to provide informed consent",{"count":141,"type":22},40,[25],"This planned randomized, single-blind clinical trial will investigate the effects of adding the Post-Isometric Relaxation (PIR) technique to a standard postural exercise program in individuals with moderate to severe temporomandibular joint dysfunction (TMD). Forty volunteers aged 18-25 years will be recruited and randomly assigned to either an experimental group (postural exercises + PIR) or a control group (postural exercises only). The intervention will be delivered three times per week for six weeks. Primary outcomes will include cervical range of motion, mandibular mobility, head anterior tilt, and thoracic kyphosis index, measured before and after the intervention. The study aims to determine whether PIR provides additional benefits to standard postural exercises in improving jaw and neck function and postural alignment in young adults with TMD.",[145,29,146],"Temporomandibular Joint Disorders","Mandibular Dysfunction",[148,149,150],"Temporomandibular Joint Dysfunction","Post-Isometric Relaxation","range of motion","2025-08-12",{"date":153,"type":45},"2025-08-19",{"date":155,"type":22},"2025-08-11",{"date":157,"type":22},"2025-09-25",{"name":159,"class":52},"Sanem ŞENER"]