[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neck-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neck-pain":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,104,0,25,[9,50,87,115,137,166,199,221,253,281,308,333,355,382,402,430,455,489,525,543,568,592,617,636,662],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100615265","stratified-targeted-engagement-from-primary-care-to-physical-therapy-steppt-100615265",false,"NCT07290361","Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)","Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT): A Pragmatic Stepped Wedge Cluster Randomized Trial","STEPPT","Inclusion Criteria\n\n* 18 years or older.\n* Identify as either Hispanic or Non-Hispanic ethnicity, inclusive of all races.\n* Seeking care for spine pain at an Adult or Adult Walk-in primary care clinic within the participating Federally Qualified Health Center (FQHC).\n* New or existing spine pain problem: A new spine pain problem is defined by a new ICD code for neck or back pain added to the problem list during a visit with a primary care physician. An existing spine pain problem is defined by an existing ICD code for neck or back pain on the problem list that is associated with a physician referral for any service during the visit related to the neck or back pain problem.\n* Signed a broad consent for the use of de-identified health information for research at the participating FQHC.\n\nExclusion Criteria:\n\n* Spine pain associated with a non-musculoskeletal etiology (e.g., infection, cancer, urological disorders, pregnancy, etc.)\n* Patients requiring urgent medical intervention (e.g., fracture, cauda equina syndrome, etc)\n* Active physical therapy referral for spine pain at the time of the index encounter.\n* Previously referred to physical therapy through the STEPPT Care Pathway.\n* Physical therapy referrals external to the FQHC will be excluded from the analysis of physical therapy adherence","ALL","18 Years",{"count":21,"type":22},17587,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn if a health system intervention called \"Stratified Targeted Engagement from Primary Care to Physical Therapy (STEPPT)\" can improve how often doctors refer Hispanic patients with spine pain to physical therapy (referral rate) and how often patients attend physical therapy after being referred (adherence rate). The main questions this study aims to answer are 1) does STEPPT improve physical therapy referral and adherence rates compared to usual care for Hispanic patients with spine pain who seek care in a Federally Qualified Health Center (FQHC) serving low income communities, and 2) how consistently do FQHC providers and staff deliver STEPPT to patients who may benefit? STEPPT will train doctors and other health care providers to educate participants on the benefits of physical therapy for spine pain and participants will receive culturally tailored handouts and videos to teach them about their spine pain and what to expect in physical therapy. Patients will also receive personalized assistance to schedule their physical therapy appointment and address potential barriers for attending the appointment.",[28,29],"Low Back Pain","Neck Pain",[31,32,33,34,35,36],"Physical therapy","Rehabilitation","Hispanic","Heatlh Services","Healthcare utilization","Federally Qualified Health Center","RECRUITING","2026-08-12",{"date":40,"type":41},"2026-08-14","ACTUAL",{"date":43,"type":41},"2025-12-01",{"date":45,"type":22},"2029-02-28",{"name":47,"class":48},"San Diego State University","OTHER",1,{"id":51,"slug":52,"hasResults":12,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":62,"conditions":63,"keywords":72,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":49},"100651571","phase-4-success-rates-and-safety-of-steroid-injections-in-managing-spinal-and-sacro-iliac-pain-cortisone-injection-spine-study-100651571","NCT07762170","Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study)","Success Rates and Safety in Managing Spinal and Sacro-Iliac Pain: A Critical Analysis","CORTISS","Inclusion Criteria:\n\n* \\>18 years of age;\n* Diagnosis of lumbar, cervical, or thoracic pain with various etiologies;\n* Eligibility to receive steroid injections for back pain, including epidural, facet joints, or SIJ injections, or other injections (e.g., local anesthetics);\n* Being willing and able to provide NRS pain ratings and PROMIS functionality ratings before the intervention, and the same scores plus IPR, fIPR, and PGIC at various follow-up points after the intervention;\n* Provide written informed consent.\n\nExclusion Criteria:\n\n* Diagnosis of dementia, Parkinson's disease or other cognitive impairments;\n* Congenital or acquired polyneuropathy;\n* Back surgery in the month before injection treatment or planned surgery in the subsequent 3 months;\n* Any clinically significant acute or chronic medical condition that in the judgment of Investigator may preclude injection in the epidural space or compromise patient safety, limit patient's ability to complete the study, and\u002For compromise the objectives of the study;\n* Participation in any other competing clinical study within 3 months prior to screening and during the study period.",{"count":59,"type":22},500,[61],"PHASE4","This study aims to analyze the efficacy and safety of different kinds of steroid injections for back pain, comparing different steroids, dosages, locations (epidural, facet joints, nerve blocks), and also the difference between injections with steroids and local anesthetics, to optimize this treatment that is currently not standardized. The investigators will compare retrospectively and prospectively the efficacy of different injections in the same patients, using mainly a parameter called integral of pain relief, which combines the percentage of pain relief provided by a treatment and its duration over time, as well as improvements in functionality.",[64,29,65,66,67,68,69,70,71],"Back Pain Lower Back","Radiculopathy Multiple Sites","Spinal Stenosis Cervicothoracic Region","Spinal Stenosis Lumbar","Failed Back Surgery Syndrome (FBSS)","Sciatica","Intervertebral Disc Disorders With Radiculopathy, Lumbar Region","Spine Osteoarthritis",[73,74,75,76,77],"epidural steroid injections","back pain treatments","pain relief","spinal steroid injections","spinal injections","2026-08-07",{"date":80,"type":41},"2026-08-13",{"date":82,"type":41},"2026-07-30",{"date":84,"type":22},"2030-03",{"name":86,"class":48},"Igor Wilderman. MD",{"id":88,"slug":89,"hasResults":12,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":95,"enrollmentInfo":96,"targetDuration":4,"studyType":23,"phases":98,"briefSummary":99,"conditions":100,"keywords":103,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":49},"100650051","scenar-therapy-in-chronic-non-specific-neck-pain-100650051","NCT07742228","SCENAR Therapy in Chronic Non-specific Neck Pain","Assessment of the Efficacy of SCENAR Therapy in the Management of Chronic Non-specific Neck Pain","C-Scenar","Inclusion Criteria:\n\n* Male or female participants aged 18 years or older\n* Patients with chronic non-specific cervical spine pain, including cervicobrachial neuralgia, persisting for at least 3 months, with no identifiable underlying cause requiring specific treatment.\n* Patients who attended a pain clinic consultation or were referred to a pain specialist during hospitalization.\n* Neck Disability Index (NDI) score of at least 30% (≥15 points).\n* Written informed consent provided prior to study participation.\n* Patient affiliated to a national health insurance\n\nExclusion Criteria:\n\n* Pregnant women\n* Skin conditions preventing SCENAR use (wounds, recent scars, skin infections)\n* Initiation or change of analgesic treatment within 15 days prior to inclusion or during the study\n* Cervical pain related to inflammatory (spondyloarthropathy, rheumatoid arthritis, chondrocalcinosis), traumatic (fractures, dislocations), tumor-related (metastases, myeloma), infectious (spondylodiscitis), or neurological (intramedullary or posterior fossa tumor) causes\n* Previous SCENAR or ECOMODYN session\n* Implanted pacemaker or defibrillator\n* Inability to understand French\n* Adults under legal protection\n* Individuals deprived of liberty or under guardianship","80 Years",{"count":97,"type":22},76,[25],"Shifting away from a medication-centered approach is a major public health priority, particularly in chronic pain management, where non-pharmacological therapies are recommended despite barriers such as limited evidence and low prescriber awareness.\n\nSCENAR (Self-Controlled Energo-Neuro Adaptive Regulation), an electrotherapy device, lacks robust randomized controlled trial data. A prior study showed effects in both active and placebo groups after a single session, supporting further investigation.\n\nThis study aims to assess whether repeated SCENAR sessions improve disability, mobility, and pain in patients with chronic neck pain.",[101,29,102],"Cervicalgia","Chronic Pain",[101,104,105],"SCENAR","Electrotherapy","2026-07-29",{"date":108,"type":41},"2026-08-03",{"date":110,"type":41},"2026-03-11",{"date":112,"type":22},"2028-07-30",{"name":114,"class":48},"Hopital Foch",{"id":116,"slug":117,"hasResults":12,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":4,"eligibilityCriteria":121,"healthyVolunteers":12,"sex":18,"minAge":122,"maxAge":4,"enrollmentInfo":123,"targetDuration":4,"studyType":23,"phases":124,"briefSummary":125,"conditions":126,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":49},"100647732","high-frequency-electroacupuncture-at-cervical-huatuo-jiaji-points-combined-with-electromagnetic-field-therapy-for-cervical-spondylotic-radiculopathy-100647732","NCT07712354","High-Frequency Electroacupuncture at Cervical Huatuo Jiaji Points Combined With Electromagnetic Field Therapy for Cervical Spondylotic Radiculopathy","Efficacy of High-Frequency Electroacupuncture at Cervical Huatuo Jiaji Points Combined With Electromagnetic Field Therapy in the Treatment of Cervical Spondylotic Radiculopathy Due to Cervical Spondylosis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Written informed consent to participate in the study.\n* Male or female patients aged 30 years or older.\n* Inpatients or outpatients diagnosed with cervical spondylotic radiculopathy caused by cervical spondylosis at Ho Chi Minh City Hospital of Traditional Medicine.\n* Clinical diagnosis of cervical spondylotic radiculopathy, including:\n* Neck pain radiating to the shoulder and\u002For upper extremity.\n* Sensory disturbance and\u002For motor deficit and\u002For abnormal deep tendon reflexes consistent with the affected cervical nerve root.\n* At least one positive provocative test (Spurling test, cervical percussion\u002Fcompression test, cervical distraction test, or shoulder abduction relief test).\n* Pain intensity of at least 3 on the Visual Analog Scale (VAS).\n* Clinical evidence of cervical spine syndrome.\n* Cervical spine X-ray demonstrating at least one degenerative finding (osteophytes, intervertebral disc space narrowing, or subchondral sclerosis).\n\nExclusion Criteria:\n\n* Cervical radiculopathy caused by conditions other than cervical spondylosis.\n* Cervical myelopathy or other spinal cord disorders requiring surgical intervention.\n* Severe systemic illness, frailty, or medical conditions requiring intensive care, or suspected malignancy indicated by unexplained fever, unexplained weight loss, immunodeficiency, or cancer.\n* Contraindications to acupuncture, including skin infection or ulceration at the acupuncture site, allergy to acupuncture needles, severe needle phobia, or psychiatric disorders preventing cooperation.\n* Current treatment with strong analgesics (including paracetamol\u002Fcodeine combinations, tramadol, or strong opioids) or other therapies that may interfere with study outcomes.\n* Implanted cardiac pacemakers or other implanted electronic medical devices (e.g., neurostimulators, implantable cardioverter-defibrillators, or insulin pumps).\n* Bleeding disorders or hematologic diseases affecting coagulation.\n* Benign or malignant tumors involving the treatment area or systemic malignancy.\n* Participation in another interventional clinical trial.\n* Inability to communicate effectively in Vietnamese.\n* Pregnant women or women with suspected pregnancy.","30 Years",{"count":5,"type":22},[25],"Cervical spondylotic radiculopathy (CSR) is one of the most common manifestations of cervical spondylosis and is characterized by neck pain radiating to the upper extremities, sensory disturbances, restricted cervical range of motion, and functional disability. Conservative treatment is recommended as the first-line management for most patients, and electroacupuncture is widely used in Traditional Medicine to relieve pain and improve function.\n\nCervical Huatuo Jiaji (EX-B2) acupuncture points are anatomically located adjacent to the cervical spinal nerve roots and may provide more targeted therapeutic effects than conventional meridian acupuncture points. Pulsed electromagnetic field (PEMF) therapy has also been used as an adjunctive physical modality to reduce pain and facilitate functional recovery.\n\nThis randomized controlled trial aims to evaluate whether high-frequency electroacupuncture at cervical Huatuo Jiaji (EX-B2) points combined with PEMF therapy provides greater improvement in pain intensity, cervical function, and safety outcomes than conventional high-frequency electroacupuncture combined with PEMF therapy in patients with cervical spondylotic radiculopathy caused by cervical spondylosis.\n\nThe primary outcome is pain intensity measured using the Visual Analog Scale (VAS). Secondary outcomes include cervical range of motion, Neck Disability Index (NDI), and treatment-related adverse events. Clinical outcomes will be assessed at baseline, after one week of treatment, and at the end of the two-week treatment period.",[127,29,128],"Cervical Spondylosis","Cervical Spondylotic Radiculopathy",{"date":130,"type":41},"2026-07-31",{"date":132,"type":41},"2026-06-02",{"date":134,"type":22},"2026-09",{"name":136,"class":48},"University of Medicine and Pharmacy at Ho Chi Minh City",{"id":138,"slug":139,"hasResults":12,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":4,"eligibilityCriteria":143,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":144,"targetDuration":146,"studyType":147,"phases":4,"briefSummary":148,"conditions":149,"keywords":151,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":49},"100649474","pre-visit-ai-symptom-checking-and-shared-decision-making-in-spine-physical-therapy-100649474","NCT07733752","Pre-Visit AI Symptom-Checking and Shared Decision-Making in Spine Physical Therapy","When AI Is the First Clinician: Impact of Pre-Visit AI Use on Presentation, Diagnostic Expectations, and Shared Decision-Making in Spine Physical Therapy","Inclusion Criteria:\n\n* Age: 18 years or older\n* Presenting for a new evaluation at an outpatient physical therapy clinic for a spine-related musculoskeletal complaint, including Neck, Thoracic, and Low back pain With or without radicular symptoms\n* Able to provide informed consent.\n* Able to read, understand, and complete study questionnaires\n\nExclusion Criteria:\n\n* Recent spinal surgery within the past 3 months, due to differing clinical pathways and management strategies.\n* Presence of serious spinal pathology under active medical management, such as:\n\nMalignancy (e.g., metastatic disease) Spinal infection Acute fracture\n\n* Cognitive impairment or other conditions that limit the ability to provide informed consent or reliably complete study measures.\n* Patients currently enrolled in another study that may influence clinical decision-making or outcomes related to spine care.",{"count":145,"type":22},200,"6 Weeks","OBSERVATIONAL","Artificial intelligence (AI) symptom-checking tools, including large language models such as ChatGPT, are increasingly used by patients before they seek care. These tools may shape patients' beliefs about their diagnosis, how serious they think their condition is, and when they decide to seek treatment. It is not yet known how this pre-visit AI use affects the initial physical therapy encounter for spine-related problems.\n\nThis prospective observational cohort study examines whether prior use of AI symptom-checking tools influences the first physical therapy evaluation in adults presenting with spine-related musculoskeletal complaints (neck, thoracic, or low back pain, with or without radicular symptoms). Consecutive patients attending an outpatient physical therapy clinic for a new evaluation are grouped as AI users or non-AI users based on whether they used such a tool for their current complaint in the previous 30 days.\n\nThe primary outcome is shared decision-making, measured with the SDM-Q-9 immediately after the initial evaluation. Secondary outcomes include stage of presentation, agreement between the patient's expected diagnosis and the clinician's classification, baseline pain and disability, functional performance, and clinical outcomes at 2 and 6 weeks. The investigators hypothesize that prior AI use is associated with differences in shared decision-making and in how patients present for care.",[28,29,150],"Radiculopathy",[152,153,154,155,156,157],"Artificial intelligence","ChatGPT","Shared decision-making","SDM-Q-9","Spine","Patient expectations","2026-07-24",{"date":106,"type":41},{"date":161,"type":41},"2026-06-10",{"date":163,"type":22},"2027-02-10",{"name":165,"class":48},"Assiut University",{"id":167,"slug":168,"hasResults":12,"nctId":169,"briefTitle":170,"officialTitle":171,"acronym":172,"eligibilityCriteria":173,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":174,"enrollmentInfo":175,"targetDuration":4,"studyType":23,"phases":177,"briefSummary":178,"conditions":179,"keywords":184,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":49},"100584442","effects-of-education-and-exercise-on-pain-psychosocial-factors-and-upper-limb-function-in-non-specific-neck-pain-100584442","NCT06889389","Effects of Education and Exercise on Pain, Psychosocial Factors, and Upper Limb Function in Non-specific Neck Pain.","Effects of Pain Neuroscience Education and Therapeutic Exercise on Pain, Catastrophizing, Kinesiophobia and Upper Limb Function in Patients With Non-specific Neck Pain.","PNE-EXNP","Inclusion Criteria:\n\n* Subjects aged between 18 and 65 years\n* Subjects with non-specific neck pain at the time of the intervention, scoring at least 3 on the NPRS scale.\n\nExclusion Criteria:\n\n* Pregnancy\n* Severe illnesses: diabetes, cancer, neurological conditions, depression, etc.\n* Subjects impairments or disorders\n* Subjects who have received physiotherapy treatment within the last month\n* Subjects currently undergoing concurrent physiotherapy treatment for this condition\n* Subjects with specific neck pain, such as any traumatic pathology, whiplash, or diagnoses associated with neurological compromise or peripheral nerve damage\n* Physiotherapy students or professional physiotherapists","65 Years",{"count":176,"type":22},81,[25],"Pain neuroscience education is currently one of the techniques being explored in physiotherapy for pain management. The benefits of this technique are gradually becoming evident in various published studies. So far, it has been widely studied for its short-term effects, but the education provided has typically been generic, not focused on exercise. However, it is suggested that this technique should be combined with exercise to achieve the expected outcomes. Therefore, pain education should be tailored to the specific physical activities the subject will perform to maximise its effectiveness. The primary aim of this study is to analyse the outcome of combining exercise with tailored pain neuroscience education on aspects such as pain, kinesiophobia, catastrophizing, exercise conceptualization, and upper limb function in subjects with neck pain. The secondary aim is to evaluate the relationship between kinesiophobia and catastrophizing and their impact on the results of various upper limb performance tests. Finally, the effects of therapeutic exercise alone will be compared with those of therapeutic exercise combined with pain neuroscience education, focusing on pain, kinesiophobia, catastrophizing, and exercise conceptualization. A double-blind, randomised clinical trial has been designed, in which three intervention protocols will be applied to 81 subjects with non-specific neck pain: education with exercise, exercise alone, and placebo alone. Subjects with non-specific neck pain who meet the inclusion criteria will be enrolled. Demographic characteristics of the subjects, as well as pain, kinesiophobia, catastrophizing, and upper limb performance test scores, will be assessed. This study aims to explore the potential relevance of a pain neuroscience education session prior to therapeutic exercise, as well as to influence the clinical recommendations made by clinicians during treatment.",[29,180,181,182,183],"Patient Education","Exercise Therapy","Fear","Pain",[185,186,187,188,189],"Neck pain","Pain neuroscience education","Exercise therapy","Kinesiophobia","Pain catastrophizing","2026-07-22",{"date":192,"type":41},"2026-07-23",{"date":194,"type":41},"2025-03-28",{"date":196,"type":22},"2027-12-30",{"name":198,"class":48},"Universidad Miguel Hernandez de Elche",{"id":200,"slug":201,"hasResults":12,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":12,"sex":18,"minAge":206,"maxAge":4,"enrollmentInfo":207,"targetDuration":4,"studyType":23,"phases":209,"briefSummary":210,"conditions":211,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":49},"100642572","efficacy-of-three-needle-dazhui-and-electroacupuncture-for-cervical-spondylosis-with-wind-cold-syndrome-100642572","NCT07640126","Efficacy of Three-Needle Dazhui and Electroacupuncture for Cervical Spondylosis With Wind-Cold Syndrome","Three-Needle Dazhui Combined With Electroacupuncture for Cervical Spondylotic Radiculopathy and Wind-Cold Syndrome: A Randomized, Single-Blind, Controlled Trial Evaluating Pain and Neck Disability","Inclusion Criteria:\n\n* Consent: Participants must voluntarily agree to participate and sign a written informed consent form.\n* Age: Individuals aged 18 years or older.\n* Pain Intensity: Patients with a baseline pain score of VAS ≥ 50 mm on the Visual Analog Scale.\n* Modern Medicine Diagnosis (Cervical Spondylotic Radiculopathy - CSR) Patients must meet the diagnostic criteria for CSR due to cervical spondylosis according to Decision 361\u002FQD-BYT, including:\n\n  * Cervical Spine Syndrome: Localized neck pain, restricted range of motion, and tenderness upon palpation of the spinous processes or paravertebral areas.\n\nRadicular Syndrome: Neck pain radiating to the occipital region, shoulder, arm, or hand.\n\n* Physical Examination: At least one positive result from the following tests: Bell-ringer sign, Spurling's test, Shoulder abduction test, or Cervical distraction test.\n* Imaging Criteria: X-ray findings (straight, lateral, or 3\u002F4 oblique views) showing at least one of the following:\n\n  1. Osteophytes (bone spurs) on the vertebral body.\n  2. Intervertebral disc space narrowing ≥ 25%.\n  3. Subchondral bone sclerosis.\n  4. Spondylolisthesis. - Traditional Chinese Medicine (TCM) Diagnosis (Wind-Cold Syndrome) Patients must satisfy at least one primary symptom and reach a total symptom score of ≥ 50% based on the following criteria:\n* Primary Symptoms: Pain in the neck and shoulder radiating to the arm accompanied by numbness; pain is the dominant feature; pain increases with cold and decreases with warmth.\n* Secondary Symptoms: Aversion to cold, aversion to wind, cold extremities, and presence or absence of sweating.\n* Tongue and Pulse: Pale tongue with a thin white coating; floating-tight or slow pulse.\n\nExclusion Criteria:\n\n* History of neck trauma.\n* Diagnosed with specific bone or joint diseases: Rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Down syndrome, cervical spina bifida, or Scheuermann's disease.\n* Severe neurological deficits: Progressive muscle weakness (motor loss) or acute, severe sensory loss indicating advanced nerve compression.\n* Vertebral-basilar artery syndrome: Headache, dizziness, tinnitus, loss of balance, or fatigue.\n* Autonomic nervous system disorders: Pain accompanied by tinnitus, visual disturbances, or vasomotor disorders in the occipital-shoulder region or arms.\n* Central motor neuron lesions: Presence of Hoffmann's sign, Babinski's sign, hyperreflexia, spasticity, urinary\u002Ffecal incontinence, or sexual dysfunction.\n* Symptoms suggesting systemic or malignant disease: Unexplained weight loss, fever, loss of appetite, personal or family history of malignant tumors, or diffuse pain and stiffness.\n* Symptoms suggesting infection: Fever, meningeal signs, or photophobia.\n* Symptoms suggesting serious acute medical conditions: Myocardial infarction (chest pain + sweating + shortness of breath) or arterial dissection (tearing pain sensation + headache + blurred vision).\n* Local or systemic contraindications: Infection or ulceration at the acupuncture site; patients who are exhausted, emaciated, or suffering from severe accompanying internal medical diseases.\n* Substance abuse: Alcohol or drug addiction.\n* Recent medication use (within the past month): Currently using analgesics or anti-inflammatory drugs that may affect results, such as Opioids, NSAIDs, Corticosteroids, Gabapentin, Pregabalin, or tricyclic antidepressants.\n* Other ongoing treatments: Currently undergoing other therapies such as acupressure, massage, or physical therapy for the neck area.","18 Days",{"count":208,"type":22},74,[25],"Cervical spondylosis is a prevalent health issue that significantly impacts quality of life, with Cervical Spondylotic Radiculopathy (CSR) accounting for 60-70% of cases\n\n* While modern medicine offers various treatments, the frequent use of painkillers often leads to undesirable side effects\n* In Traditional Chinese Medicine, electroacupuncture is a safe and effective method recognized by the Ministry of Health for treating this condition\n* The \"Three-Needle Dazhui\" technique is a specialized acupuncture method that simultaneously uses three needles at the Dazhui (GV14) point to strongly activate Yang Qi and dispel cold, making it particularly suitable for the Wind-Cold syndrome. This study aims to evaluate whether the combination of the Three-Needle Dazhui technique and electroacupuncture yields better results in pain reduction and functional improvement compared to electroacupuncture alone in patients with cervical spondylosis and Wind-Cold syndrome.",[127,212,29,128],"Wind-Cold Syndrome","2026-07-17",{"date":215,"type":41},"2026-07-20",{"date":217,"type":41},"2026-06-01",{"date":219,"type":22},"2028-06",{"name":136,"class":48},{"id":222,"slug":223,"hasResults":12,"nctId":224,"briefTitle":225,"officialTitle":226,"acronym":4,"eligibilityCriteria":227,"healthyVolunteers":12,"sex":18,"minAge":228,"maxAge":229,"enrollmentInfo":230,"targetDuration":232,"studyType":147,"phases":4,"briefSummary":233,"conditions":234,"keywords":236,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":252},"100634746","safety-and-effectiveness-of-ultrasound-guided-pharmacopuncture-for-spinal-diseases-100634746","NCT07543692","Safety and Effectiveness of Ultrasound-guided Pharmacopuncture for Spinal Diseases","Safety and Effectiveness of Ultrasound-guided Pharmacopuncture for Spinal Diseases: A Multi-center, Registry Study","Inclusion Criteria:\n\n1. Patients diagnosed with spinal diseases (KCD codes M and S).\n2. Patients whose Numeric Rating Scale (NRS) score for the most predominant pain (neck pain with upper limb radiating pain OR low back pain with lower limb radiating pain) caused by spinal diseases is 5 or higher.\n3. Outpatients or inpatients scheduled to utilize an ultrasound scan during pharmacopuncture (the decision to perform ultrasound-guided pharmacopuncture is made according to the clinician's routine medical judgment, not for research purposes).\n4. Patients who voluntarily agree to participate in the clinical study and sign the informed consent form.\n\nExclusion Criteria:\n\n1. Patients who have difficulty completing the written informed consent form.\n2. Women who are pregnant, planning to become pregnant, or breastfeeding.\n3. Patients deemed inappropriate for study participation by the investigator due to severe underlying diseases (e.g., cancer or other malignant neoplasms) that may interfere with treatment effects or result interpretation.\n4. Individuals who are deemed unsuitable for participation in the clinical study by the researcher.","19 Years","69 Years",{"count":231,"type":22},600,"8 Weeks","This multi-center registry study aims to evaluate the safety and effectiveness of ultrasound-guided pharmacopuncture for patients diagnosed with spinal diseases. A total of 600 patients, aged 19 to under 70 years, will be enrolled across six Korean medicine hospitals. Eligible participants must have a pain Numeric Rating Scale (NRS) of 5 or higher for their most dominant spinal pain, which includes neck pain with upper extremity radiating pain, or low back pain with lower extremity radiating pain. As a non-interventional observational study, it will include patients who are already planned to receive ultrasound-guided pharmacopuncture as part of their routine clinical care. The primary outcome is the change in the most dominant spinal pain intensity measured by the NRS from baseline to 4 weeks. Secondary outcomes include functional disability evaluated using the Neck Disability Index (NDI) or Oswestry Disability Index (ODI), quality of life using the EQ-5D-5L, and patient satisfaction. Safety will be closely monitored by assessing all adverse events at every visit, evaluating their incidence, severity, and causality related to the procedure. Participants will be selected based on strict inclusion and exclusion criteria to ensure safety and consistency. Ethical standards including informed consent, data privacy, and ongoing safety monitoring will be rigorously upheld throughout the study.",[235,29,28,150],"Spinal Disease",[237,238,239,240,241,242],"Pharmacopuncture","Ultrasound-guided","Registry","Observational Study","Korean Medicine","Spinal Pain","2026-07-15",{"date":245,"type":41},"2026-07-16",{"date":247,"type":41},"2026-04-29",{"date":249,"type":22},"2027-12-31",{"name":251,"class":48},"Jaseng Medical Foundation",6,{"id":254,"slug":255,"hasResults":12,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":4,"eligibilityCriteria":259,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":260,"targetDuration":4,"studyType":23,"phases":262,"briefSummary":263,"conditions":264,"keywords":265,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":271,"lastUpdatePostDateStruct":272,"startDateStruct":274,"completionDateStruct":276,"leadSponsor":278,"locationsCount":280},"100543869","contextual-factors-enriched-standard-care-on-mechanical-neck-pain-100543869","NCT06361472","Contextual Factors-Enriched Standard Care on Mechanical Neck Pain","A Two-Center, Investigator-Blinded, Randomized, 4-Week, Parallel-Group, Superiority Study Comparing Contextual Factors-Enriched Standard Care Versus Standard Care Only for Patients With Mechanical Neck Pain (ContextualizAR Trial)","Inclusion Criteria:\n\n* Aged \\>18.\n* Neck pain for more than 4 weeks without signs or symptoms suggestive of major structural pathology.\n* Read, write, and understand the Spanish language.\n* Signed consent form.\n\nExclusion Criteria:\n\n* Numeric Pain Reporting Scale (NPRS) \\\u003C 3 points (to ensure the exclusion of patients with minor disorders).\n* Northwick Park Neck Pain Questionnaire (NPQ) \\\u003C 10 points (to ensure the exclusion of patients with minor disorders).\n* History of cervical spine trauma, fracture, or surgical procedures.\n* Signs and symptoms of cervical myelopathy and\u002For cervical radiculopathy (to rule out cervical radicular pain, the Spurling Test, the Upper Limb Tension Test for the median nerve, and the Traction\u002FDistraction test will be used).\n* Red flags or serious pathologies, such as malignancy, inflammatory or rheumatic diseases, infections, and vascular conditions like cervical artery insufficiency.",{"count":261,"type":22},94,[25],"The primary purpose of this study will be to determine if a CFs-Enriched Standard Care approach is an effective treatment for mechanical neck pain in terms of reducing pain and improving function. We hypothesize that a 4-week CFs-Enriched Standard Care approach will be superior to Standard Care alone in terms of patient-reported disability and pain, with measurements conducted using the Northwick Park Neck Pain Questionnaire and the Numeric Pain Rating Scale, respectively.\n\nThis will be an assessor-blinded, 2-group (1:1) randomized clinical trial aiming to enroll 94 participants with neck pain persisting for more than 4 weeks. Both groups will undergo 4 weeks of standard care twice weekly, following established clinical practice guidelines. In the intervention group, CFs will be enhanced, encompassing the physical, psychological, and social elements inherent in the clinical encounter, based on existing evidence.\n\nThe primary outcomes will encompass changes in Pain and Disability after 4 weeks of treatment, with a follow-up reassessment at week 12 post-treatment. Secondary outcomes will include changes in Active Range of Motion, Global Rating of Change, and Satisfaction with treatment. The change between groups after treatment and at the 12-week follow-up will be reported for all outcomes, considering the difference from scores recorded at baseline.\n\nThis study will be conducted at two sites in Buenos Aires, Argentina. Randomization will be stratified by site to ensure balanced allocation across centers.",[29],[266,267,268,269,270],"neck pain","functional status","contextual factors","placebo","randomized controlled trial","2026-07-04",{"date":273,"type":41},"2026-07-08",{"date":275,"type":41},"2024-05-02",{"date":277,"type":22},"2027-07",{"name":279,"class":48},"Universidad Nacional de la Matanza",2,{"id":282,"slug":283,"hasResults":12,"nctId":284,"briefTitle":285,"officialTitle":285,"acronym":4,"eligibilityCriteria":286,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":174,"enrollmentInfo":287,"targetDuration":4,"studyType":147,"phases":4,"briefSummary":289,"conditions":290,"keywords":295,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":299,"lastUpdatePostDateStruct":300,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":49},"100645113","the-relationship-between-lost-extremity-percentage-and-postural-control-neck-and-low-back-pain-daily-living-activities-and-reaction-time-in-individuals-with-unilateral-upper-limb-amputation-100645113","NCT07677969","The Relationship Between Lost Extremity Percentage and Postural Control, Neck and Low Back Pain, Daily Living Activities, and Reaction Time in Individuals With Unilateral Upper Limb Amputation","Inclusion Criteria:\n\n* Adults aged 18-65 years\n* Unilateral upper limb amputation\n* Use of a myoelectric or bionic prosthesis for at least 1 year\n* Current prosthesis use for a minimum of 3 months\n\nExclusion Criteria:\n\n* Bilateral upper limb amputation\n* Additional amputation of another limb\n* Use of passive or cosmetic prosthesis\n* Presence of neurological or other significant orthopedic disorders unrelated to amputation",{"count":288,"type":22},15,"This observational study aims to examine the relationship between the percentage of limb loss and functional outcomes in individuals with unilateral upper limb amputation. Upper limb amputation can affect posture, balance control, pain levels, daily living activities, hand function, and reaction time. However, limited research has investigated how the amount of limb loss influences these outcomes.\n\nParticipants between 18 and 65 years of age who use a myoelectric or bionic prosthesis will undergo a series of assessments. These assessments include measurements of postural control using a force platform, posture analysis, evaluation of neck and low back pain using a visual analog scale, daily living activities using a validated questionnaire, hand dexterity using the Box and Block Test, and reaction time using a visual stimulus device.\n\nThe study does not involve any intervention or treatment. All evaluations will be performed during a single assessment session. The results of this study may help improve rehabilitation planning and provide better understanding of functional changes associated with different levels of limb loss in people with upper limb amputation.",[291,292,29,28,293,294],"Upper Limb Amputation","Postural Control","Daily Activities","Reaction Time",[291,292,29,296,297,298],"low back pain","Daily Living Activities","reaction time","2026-06-30",{"date":301,"type":41},"2026-07-01",{"date":303,"type":41},"2026-01-01",{"date":305,"type":22},"2026-12-01",{"name":307,"class":48},"Hacettepe University",{"id":309,"slug":310,"hasResults":12,"nctId":311,"briefTitle":312,"officialTitle":313,"acronym":314,"eligibilityCriteria":315,"healthyVolunteers":12,"sex":18,"minAge":316,"maxAge":174,"enrollmentInfo":317,"targetDuration":4,"studyType":23,"phases":319,"briefSummary":320,"conditions":321,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":325,"lastUpdatePostDateStruct":326,"startDateStruct":328,"completionDateStruct":330,"leadSponsor":331,"locationsCount":49},"100646946","ischemic-compression-and-home-exercise-in-non-specific-neck-pain-100646946","NCT07685418","Ischemic Compression and Home Exercise in Non-Specific Neck Pain","Evaluation of the Effects of Ischemic Compression Combined With Home Exercise on Pain Intensity and Quality of Life in Individuals With Chronic Non-Specific Neck Pain","NSNP","Inclusion Criteria:\n\n* Individuals aged between 18 and 65 years.\n* Diagnosis of non-specific neck pain for at least 3 months.\n* Diagnosis of non-specific neck pain for at least 3 months.\n* Voluntarily agreeing to participate and signing the informed consent form.\n\nExclusion Criteria:\n\n* Presence of specific causes of neck pain (cervical disc herniation, radiculopathy, spinal stenosis, tumor, infection, rheumatic diseases, etc.).\n* Having undergone surgical intervention in the neck region within the last 6 months.\n* History of neurological disease.\n* History of surgery in the cervical or thoracic vertebrae.\n* Presence of impaired skin integrity in the application area.","17 Years",{"count":318,"type":22},52,[25],"The purpose of this study is to investigate the effects of ischemic compression combined with home exercise on pain, cervical range of motion, neck disability level, and quality of life in individuals with non-specific neck pain. Participants will be divided into two groups: a treatment group receiving ischemic compression plus home exercises, and a control group receiving only home exercises. The study aims to provide clinical evidence regarding the effectiveness of combined treatment approaches for non-specific neck pain.",[322,323,324,29],"Myofascial Trigger Points","Musculoskeletal Pain","Non-specific Neck Pain","2026-06-29",{"date":327,"type":41},"2026-07-06",{"date":329,"type":41},"2026-05-13",{"date":243,"type":22},{"name":332,"class":48},"Istanbul Rumeli University",{"id":334,"slug":335,"hasResults":12,"nctId":336,"briefTitle":337,"officialTitle":338,"acronym":4,"eligibilityCriteria":339,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":95,"enrollmentInfo":340,"targetDuration":4,"studyType":23,"phases":342,"briefSummary":343,"conditions":344,"keywords":346,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":325,"lastUpdatePostDateStruct":348,"startDateStruct":349,"completionDateStruct":351,"leadSponsor":353,"locationsCount":280},"100643724","muscle-position-and-dry-needling-efficacy-100643724","NCT07629141","Muscle Position and Dry Needling Efficacy","The Importance of Muscle Position in the Effectiveness of Dry Needling Technique","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Neck pain lasting more than 3 months\n* Current neck pain greater than 3\u002F10 on the VAS (Visual Analog Scale)\n* Presence of active trigger points in the upper trapezius muscle, meeting the following criteria: Painful point within a taut band whose palpation reproduces the patient's symptoms.\n\nExclusion Criteria:\n\n* Neck pain with a medical diagnosis (fractures, arthritis, fibromyalgia, etc.)\n* Radicular pain (paresthesia, burning, electric shocks)\n* Whiplash or any recent trauma\n* Previous surgery\n* Treatment by another physiotherapist within the last 3 months\n* Infections\n* Needle phobia\n* Use of anticoagulant medications\n* Pregnancy\n* Fibromyalgia\n* Metal allergies\n* Cognitive deficits or communication problems",{"count":341,"type":22},80,[25],"Currently, no previous studies have investigated how the position of a muscle before dry needling may influence the outcome and effectiveness of the treatment.\n\nThis study aims to demonstrate whether the position of the upper trapezius muscle during dry needling treatment influences the outcome of that treatment in subjects with neck pain.\n\nA total of 46 participants with chronic neck pain will be recruited and randomly assigned to two groups: a dry needling group with the muscle in a stretched position and a dry needling group with the muscle in a shortened position. A total of two treatment sessions will be performed, separated by a 7-day interval. The primary outcome measure will be the intensity of neck and head pain, measured using the visual analog scale (VAS). Other variables to be measured include the cervical disability index, kinesiophobia, and catastrophizing (using a self-completion questionnaire), as well as participants' expectations and post-needling pain.",[29,345],"Headache",[347,323],"dry needling",{"date":301,"type":41},{"date":350,"type":41},"2026-06-08",{"date":352,"type":22},"2026-12-15",{"name":354,"class":48},"University of Alcala",{"id":356,"slug":357,"hasResults":12,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":4,"eligibilityCriteria":361,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":174,"enrollmentInfo":362,"targetDuration":4,"studyType":23,"phases":364,"briefSummary":365,"conditions":366,"keywords":367,"overallStatus":372,"whyStopped":4,"lastUpdateSubmitDate":373,"lastUpdatePostDateStruct":374,"startDateStruct":376,"completionDateStruct":378,"leadSponsor":380,"locationsCount":4},"100629046","chiropractic-care-for-chronic-neck-pain-a-pilot-study-100629046","NCT07469553","Chiropractic Care for Chronic Neck Pain: A Pilot Study","Chiropractic Care for Chronic Neck Pain: A Pilot Randomized Controlled Trial Evaluating Feasibility, Clinical Outcomes, and EEG\u002FGait Biomarkers","Inclusion Criteria:\n\nAdults aged 18-65 years Diagnosis of CNP (e.g., nociceptive, neuropathic, or nociplastic origin) occurring ≥5 days per week for ≥3 consecutive months.\n\nAverage neck pain intensity ≥3 on a 0-10 Numerical Rating Scale (NRS) during the past week (0 = no pain at all; 10 = worst neck pain imaginable).\n\nNeck Disability Index (NDI) score ≥5 \\[37\\] 10-item instrument with scores ranging from 0 (no disability) to 50 (complete disability).\n\nWillingness to complete all study procedures. Willingness to be randomized to either of the two intervention groups. Fluent in English.\n\nExclusion Criteria:\n\n* Currently receiving chiropractic care or have received chiropractic care within the past 12 months.\n\nParticipation in ≥1 session per week of mind-body or rehabilitation therapies (e.g., physical therapy, yoga, tai chi, Qigong) within the past 12 months.\n\nAny disability precluding exercise participation. Pregnancy. Pregnancy status will be assessed by self-report only. No pregnancy testing will be conducted for the purposes of this study.\n\nPrior cervical spine surgery or any spinal surgery within the past year. Active disability or accident-related compensation claim. Signs or symptoms of major systemic illness or unstable medical conditions (e.g., Parkinson's disease, cancer).\n\nPsychiatric conditions requiring immediate treatment or likely to impair protocol compliance.\n\nCNP attributable to on-neuromusculoskeletal source. Inflammatory arthritis. History of stroke, carotid dissection, or vertebral artery dissection. Presence of a neurological disorder. Suspected or confirmed pathological hypermobility. Receipt of interventional pain management to the cervical spine within 4 weeks prior to enrollment or planned during the study period.\n\nAvailable diagnostic imaging demonstrating contraindications to study treatments (e.g., cervical myelopathy, substantial disc derangement).\n\nClinical screening findings indicating a need for diagnostic imaging. High risk for adverse events (AEs) related to any study treatment. Inadequate transportation to attend scheduled study visits. Contraindications to standard, non-invasive scalp EEG procedures (e.g., open scalp wounds, active skin infections, or unhealed surgical sites at electrode placement locations; recent craniotomy or skull defect that would interfere with safe electrode placement, Implanted neurostimulation devices; known seizure disorders or epilepsy; medical conditions for which EEG activation procedures are contraindicated (stroke, hyperventilation).",{"count":363,"type":22},60,[25],"This pilot randomized controlled trial will evaluate the feasibility and preliminary clinical effects of multimodal chiropractic care for adults with chronic neck pain. Forty participants will be randomized to receive either multimodal chiropractic care plus enhanced usual care or enhanced usual care alone. Feasibility outcomes include recruitment, retention, adherence, and safety. Clinical outcomes include pain intensity, neck-related disability, physical and psychological function, and quality of life. Exploratory electroencephalography (EEG) and gait assessments will examine potential neurophysiological and biomechanical biomarkers associated with treatment response.",[29],[266,368,369,370,371],"chiropractic care","EEG","gait","randomized trial","NOT_YET_RECRUITING","2026-06-24",{"date":375,"type":41},"2026-06-26",{"date":377,"type":22},"2026-08-01",{"date":379,"type":22},"2027-09-30",{"name":381,"class":48},"Brigham and Women's Hospital",{"id":383,"slug":384,"hasResults":12,"nctId":385,"briefTitle":386,"officialTitle":386,"acronym":4,"eligibilityCriteria":387,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":388,"enrollmentInfo":389,"targetDuration":4,"studyType":23,"phases":391,"briefSummary":392,"conditions":393,"keywords":4,"overallStatus":372,"whyStopped":4,"lastUpdateSubmitDate":394,"lastUpdatePostDateStruct":395,"startDateStruct":397,"completionDateStruct":398,"leadSponsor":400,"locationsCount":49},"100643912","effect-of-brueggers-exercise-in-chronic-mechanical-neck-pain-with-forward-head-posture-100643912","NCT07669844","Effect of Bruegger's Exercise in Chronic Mechanical Neck Pain With Forward Head Posture","Inclusion Criteria:\n\n* Participant with neck pain and craniovertebral angle value lower than 50°.\n* Numeric pain rating score above 3.\n* More than 10 on neck disability index.\n\nExclusion Criteria:\n\n* Arthritis (or other inflammatory diseases).\n* Locoregional tumor or metastasis .\n* Myopathy .\n* Severe psychiatric disorders.\n* Previous neck surgery.\n* Fibromyalgia.","35 Years",{"count":390,"type":22},24,[25],"The purpose of the study is to investigate the effect of adding Bruegger's exercises on conventional exercise program in treatment of forward head posture.",[29],"2026-06-21",{"date":396,"type":41},"2026-06-25",{"date":301,"type":22},{"date":399,"type":22},"2026-09-16",{"name":401,"class":48},"Cairo University",{"id":403,"slug":404,"hasResults":12,"nctId":405,"briefTitle":406,"officialTitle":407,"acronym":4,"eligibilityCriteria":408,"healthyVolunteers":409,"sex":18,"minAge":410,"maxAge":411,"enrollmentInfo":412,"targetDuration":4,"studyType":23,"phases":414,"briefSummary":415,"conditions":416,"keywords":418,"overallStatus":372,"whyStopped":4,"lastUpdateSubmitDate":422,"lastUpdatePostDateStruct":423,"startDateStruct":425,"completionDateStruct":426,"leadSponsor":428,"locationsCount":49},"100641992","effects-of-music-therapy-in-chronic-neck-pain-100641992","NCT07658729","Effects of Music Therapy in Chronic Neck Pain","The Effects of Music Therapy on Pain, Cervical Position Sense, and Balance in Individuals With Chronic Neck Pain","Inclusion Criteria:\n\n* Being between 20-50 years old\n* Having experienced neck pain for at least 3 months\n* Having a resting neck pain score of 3 or higher on the Numeric Pain Scale\n* Being willing to participate in the study\n\nExclusion Criteria:\n\n* Patients with surgical indications for and\u002For who have undergone surgery in the cervical region\n* Having received physiotherapy and\u002For other treatment for neck pain within the last year\n* Those with a history of trauma and systemic disease in the cervical region (malignant condition, systemic rheumatic disease, etc.)\n* Having additional musculoskeletal diseases that may also affect the cervical region (thoracic outlet and scoliosis, etc.)\n* Having a psychiatric illness\n* Being visually impaired",true,"20 Years","50 Years",{"count":413,"type":22},19,[25],"This study aims to investigate the effects of music therapy on pain, cervical position sense, and balance in individuals with chronic neck pain. Chronic neck pain is a common musculoskeletal disorder that may impair proprioception and postural control, negatively affecting daily functioning and quality of life. Music therapy is a safe, low-cost, and non-pharmacological intervention with potential benefits for pain management and sensorimotor function; however, evidence regarding its effects in musculoskeletal rehabilitation is limited. In this study, nineteen individuals with chronic neck pain will listen to instrumental Turkish Classical Music in the Nihavend mode for 60 minutes. Pain intensity, cervical position sense, and static and dynamic balance will be assessed before and after the intervention. The findings are expected to provide evidence for the clinical use of music therapy as an adjunctive treatment in chronic neck pain rehabilitation.",[29,183,417],"Music Therapy",[266,419,420,421],"music therapy","proprioception","balance","2026-06-18",{"date":424,"type":41},"2026-06-23",{"date":301,"type":22},{"date":427,"type":22},"2026-08-30",{"name":429,"class":48},"Karabuk University",{"id":431,"slug":432,"hasResults":12,"nctId":433,"briefTitle":434,"officialTitle":435,"acronym":4,"eligibilityCriteria":436,"healthyVolunteers":12,"sex":18,"minAge":410,"maxAge":437,"enrollmentInfo":438,"targetDuration":4,"studyType":23,"phases":440,"briefSummary":441,"conditions":442,"keywords":443,"overallStatus":372,"whyStopped":4,"lastUpdateSubmitDate":350,"lastUpdatePostDateStruct":448,"startDateStruct":450,"completionDateStruct":451,"leadSponsor":453,"locationsCount":49},"100643459","effects-of-sahrmanns-approach-in-patients-with-cervical-extension-syndrome-100643459","NCT07641959","Effects of Sahrmann's Approach in Patients With Cervical Extension Syndrome","Effects of Sahrmann's Approach on Pain, Range of Motion, Craniovertebral Angle and Function in Patients With Cervical Extension Syndrome","Inclusion Criteria:\n\n* Adults between 20-40 years, NPRS score 4-6 , positive tests cervical flexion, extension, protraction and retraction and Cervical Nodding Against Wall\n\nExclusion Criteria:\n\nScoliosis, Pregnant females, Any active infection or disese","40 Years",{"count":439,"type":22},54,[25],"Cervical Extension Syndrome (CES) is a form of postural dysfunction under the Movement System Impairment (MSI) classification. It has more prevalence among adults due to prolonged poor posture and sedentary lifestyles. This condition involves a forward head position,, increased thoracic curve, and altered movement patterns. This resulting in neck pain and impaired function. The Sahrmann's approach is a biomechanical principle that puts emphasizes on muscle activation, correction of postural impairments, and restoration of movement control through targeted exercises. The objective of the study will be to compare the effects of Sahrmann's Approach on Pain, ROM, craniovertebral angle and function in patients with Cervical Extension Syndrome.",[29],[444,445,446,447],"pain","range of motion","craniovertebral angle","function",{"date":449,"type":41},"2026-06-11",{"date":301,"type":22},{"date":452,"type":22},"2026-11-01",{"name":454,"class":48},"Riphah International University",{"id":456,"slug":457,"hasResults":12,"nctId":458,"briefTitle":459,"officialTitle":460,"acronym":461,"eligibilityCriteria":462,"healthyVolunteers":12,"sex":18,"minAge":463,"maxAge":464,"enrollmentInfo":465,"targetDuration":4,"studyType":23,"phases":467,"briefSummary":468,"conditions":469,"keywords":472,"overallStatus":372,"whyStopped":4,"lastUpdateSubmitDate":481,"lastUpdatePostDateStruct":482,"startDateStruct":484,"completionDateStruct":485,"leadSponsor":487,"locationsCount":49},"100642778","acute-effect-of-diaphragmatic-breathing-on-postoperative-upper-trapezius-pain-100642778","NCT07634588","ACUTE EFFECT OF DIAPHRAGMATIC BREATHING ON POSTOPERATIVE UPPER TRAPEZIUS PAIN","EVALUATION OF THE ACUTE EFFECTS OF DIAPHRAGMATIC BREATHING EXERCISES ADDED TO SOFT TISSUE MOBILIZATION AND PERCUSSIVE THERAPY ON PAIN, FUNCTIONALITY, AND PRESSURE PAIN THRESHOLD IN THE UPPER TRAPEZIUS MUSCLE OF SURGICAL NURSES AFTER SURGERY","TRAP-BREATHE","Inclusion Criteria:\n\n* Aged between 22 and 55 years.\n* Operating room nurse actively working in the hospital operating theater.\n* Reporting upper trapezius pain and tenderness within 30 minutes after completion of a surgical procedure.\n* Willing to participate and able to provide written informed consent.\n\nExclusion Criteria:\n\n* History of trauma, surgery, or chronic disease affecting the neck or shoulder region.\n* Regular participation in breathing exercise programs.\n* Psychiatric disorders requiring anxiolytic or antidepressant medication.\n* Pregnancy.\n* Skin disease, infection, or open wound in the treatment area.\n* Severe cardiovascular disease or uncontrolled hypertension.\n* Contraindications to manual therapy, soft tissue mobilization, percussive therapy, or breathing exercises.","22 Years","55 Years",{"count":466,"type":22},38,[25],"This randomized controlled trial aims to investigate the acute effects of diaphragmatic breathing exercises added to soft tissue mobilization and percussive therapy on pain intensity, functional disability, and pressure pain threshold in operating room nurses experiencing upper trapezius pain after surgery-related work activities.\n\nParticipants will be operating room nurses working in a hospital operating theater who report upper trapezius pain and tenderness within 30 minutes after completing a surgical procedure. Eligible participants will be randomly assigned to either an intervention group receiving soft tissue mobilization, percussive therapy, and diaphragmatic breathing exercises, or a control group receiving soft tissue mobilization and percussive therapy alone.\n\nPain intensity will be assessed using the Visual Analog Scale (VAS), functional disability using the Neck Disability Index (NDI), and mechanical pain sensitivity using Pressure Pain Threshold (PPT) measurements. Assessments will be performed immediately before and after a single treatment session. The study aims to determine whether the addition of diaphragmatic breathing exercises provides additional benefits in reducing pain and improving function in the acute postoperative working period of operating room nurses.",[29,470,471],"Myofascial Pain Syndrome","Work-Related Musculoskeletal Disorders",[473,474,475,476,477,478,479,323,480],"Upper Trapezius Pain","Diaphragmatic Breathing","Soft Tissue Mobilization","Percussive Therapy","Operating Room Nurses","Pressure Pain Threshold","Neck Disability Index","Acute Pain","2026-06-05",{"date":483,"type":41},"2026-06-09",{"date":481,"type":22},{"date":486,"type":22},"2026-08",{"name":488,"class":48},"Istanbul Aydın University",{"id":490,"slug":491,"hasResults":12,"nctId":492,"briefTitle":493,"officialTitle":494,"acronym":495,"eligibilityCriteria":496,"healthyVolunteers":409,"sex":497,"minAge":19,"maxAge":498,"enrollmentInfo":499,"targetDuration":4,"studyType":23,"phases":501,"briefSummary":503,"conditions":504,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":517,"lastUpdatePostDateStruct":518,"startDateStruct":519,"completionDateStruct":521,"leadSponsor":523,"locationsCount":49},"100640820","phase-1-hormones-outcomes-and-pain-pathways-in-exercise-study-100640820","NCT07579182","Hormones, Outcomes, and Pain Pathways in Exercise Study","Mechanical and Non-mechanical Contributions to Chronic Neck, Shoulder, Arm, and Back Pain in Full-busted Women","HOPE","Inclusion Criteria:\n\n1. Able to provide informed consent\n2. Age of 18 to 60 years\n3. Assigned female sex at birth\n4. Right-handed by self-declaration\n5. Willing to participate in one online testing session and up to four in-person testing sessions\n6. Bra band size between 32-40\"\n7. International Physical Activity Questionnaire - Short Form (IPAQ-SF) score of 2 or higher\n8. An answer of \"NO\" to any item of the general health questions of the PARQ+\n9. No history of surgery to the: back, neck, or shoulders or joint replacement\n10. No history of implanted pacemakers or other stimulation devices\n11. No history of spinal cord injury (SCI)\n\nExclusion Criteria:\n\n1. Inability to provide informed consent\n2. Age 17 years old or younger or 61 years or older\n3. Assigned male sex at birth\n4. Left-handed by self-declaration\n5. Not willing to participate in one online testing session and up to four in-person testing sessions\n6. Bra band size greater than 40\" or less than 32\"\n7. IPAQ-SF score of 1 or lower\n8. An answer of \"YES\" to any item of the general health questions of the PARQ+\n9. History of limb amputation (upper or lower extremity)\n10. Presence of open pressure sores on the upper or lower extremities\n11. Currently pregnant or lactating\u002Fbreastfeeding\n12. History of surgery to the: back, neck, or shoulders or joint replacement\n13. History of breast cancer and\u002For mastectomy\n14. History of implanted pacemakers or other stimulation devices\n15. History of spinal cord injury (SCI)\n16. History of joint disease including osteoarthritis and\u002For Rheumatoid Arthritis\n17. History of the following neurological diseases: Cerebrovascular accident (CVA, stroke), Alzheimer's Disease (AD), Dementia (of any form), Huntington's Disease, Traumatic Brain Injury (TBI), Spinal cord injury (SCI), Multiple Sclerosis (MS), Parkinson's Disease (PD), Polio, Paraproteinaemic Demyelinating Neuropathy (PDN) and\u002For Monoclonal Gammopathy of Undetermined Significance (MGUS), Myasthenia Gravis, Muscular Dystrophy, Guillain-Barré Syndrome, Scoliosis, Charcot-Marie-Tooth Disorder or other hereditary neuropathies\n\nAdditional Inclusion Criteria for Intervention Group:\n\na. Self-declared breast size of D-I cup (US sizes: D, E, F, G, H)\n\nAdditional Inclusion Criteria for the Control Group:\n\na. Self-declared breast size of A-C cup (US sizes: AA, A, B, C)","FEMALE","60 Years",{"count":500,"type":22},140,[502],"PHASE1","The goal of the proposed project is to evaluate a mechanical intervention (sports bras designed specifically for full busted women) to alleviate neck, shoulder, arm, and back pain in full-busted women and investigate the contribution of non-mechanical pathways associated with this type of pain in women. Specifically, the investigators will investigate how sex-hormones, inflammation, and remapping of specific regions of the brain contribute to the manifestation of neck, shoulder, arm, and back pain in full-busted women across the lifespan.",[505,506,507,508,29,509,510,511,512,513,514,515,516],"Breast Pain","Mastalgia","Back Pain","Back Pain, Low","Chest Pain","Activity, Motor","Healthy Aging","Weight, Body","Inflammation","Gonadal Steroid Hormones","Neuronal Plasticity","Neuromuscular Manifestations","2026-05-28",{"date":132,"type":41},{"date":520,"type":41},"2026-05-17",{"date":522,"type":22},"2029-09",{"name":524,"class":48},"University of Houston",{"id":526,"slug":527,"hasResults":12,"nctId":528,"briefTitle":529,"officialTitle":529,"acronym":4,"eligibilityCriteria":530,"healthyVolunteers":12,"sex":497,"minAge":411,"maxAge":498,"enrollmentInfo":531,"targetDuration":4,"studyType":23,"phases":533,"briefSummary":534,"conditions":535,"keywords":4,"overallStatus":372,"whyStopped":4,"lastUpdateSubmitDate":517,"lastUpdatePostDateStruct":536,"startDateStruct":538,"completionDateStruct":540,"leadSponsor":542,"locationsCount":49},"100640486","effect-of-sensory-motor-training-for-neck-muscles-on-hand-grip-strength-in-post-menopausal-fibromyalgia-neck-pain-100640486","NCT07624188","Effect of Sensory Motor Training for Neck Muscles on Hand Grip Strength in Post-menopausal Fibromyalgia Neck Pain.","Inclusion Criteria:\n\n* Fifty post-menopausal women clinically diagnosed with fibromyalgia neck pain for more than 3 months.\n* Their age will be ranged from 50-60 years old.\n* Their body mass index (BMI) will be less than 30 kg\u002Fm².\n* Their hand grip strength is less than 20 kg for dominant hand as measured by hand-held dynamometer.\n* Their neck pain score is ≥ 4 as measured by the visual analogue scale (VAS).\n* The right hand is the dominant for all of them.\n\nExclusion Criteria:\n\n* Participants will be excluded from the study if they have:\n* Recent cervical trauma or surgery.\n* Neurological disorders.\n* Diabetes mellitus.",{"count":532,"type":22},50,[25],"This study will be conducted to investigate the effect of sensory motor training for neck muscles on hand grip strength in post-menopausal fibromyalgia neck pain.",[29],{"date":537,"type":41},"2026-06-03",{"date":539,"type":22},"2026-06",{"date":541,"type":22},"2026-10-30",{"name":401,"class":48},{"id":544,"slug":545,"hasResults":12,"nctId":546,"briefTitle":547,"officialTitle":548,"acronym":4,"eligibilityCriteria":549,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":174,"enrollmentInfo":550,"targetDuration":552,"studyType":147,"phases":4,"briefSummary":553,"conditions":554,"keywords":556,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":560,"lastUpdatePostDateStruct":561,"startDateStruct":563,"completionDateStruct":565,"leadSponsor":566,"locationsCount":49},"100636562","common-pain-mechanisms-in-migraine-migraine-related-neck-pain-and-lower-back-pain-a-cross-sectional-study-100636562","NCT07567300","Common Pain Mechanisms in Migraine, Migraine-Related Neck Pain, and Lower Back Pain: A Cross Sectional Study","From Mechanisms to Clinical Evidence: A Cross-Sectional Study of Common Pain Mechanisms in Migraine, Migraine-Related Neck Pain, and Lower Back Pain","Inclusion Criteria:\n\n* Being between 18 and 65 years of age,\n* Being able to read and understand Turkish,\n* Agreeing to participate voluntarily,\n* Having an episodic or chronic migraine diagnosis according to the International Classification of Headache Disorders Edition 3 criteria;\n* Having neck pain and\u002For lower back pain without any underlying diagnosis accompanying the migraine diagnosis.\n\nExclusion Criteria:\n\n* A history of neurological disorder (e.g., Multiple Sclerosis),\n* Inflammatory rheumatic disorders (e.g., Rheumatoid Arthritis), generalized chronic pain syndromes (e.g., Fibromyalgia),\n* Any other headache disease, any other systemic disease,\n* Acute fracture and infection,\n* Spinal surgery or spinal disease diagnosis within the last 6 months,\n* Serious musculoskeletal trauma within the last 6 months,\n* Pregnancy,\n* A cognitive or psychiatric condition that would prevent completion of the questionnaires,\n* In the control group without a migraine diagnosis,\n* A history of recurrent headaches within the last year.",{"count":551,"type":22},179,"1 Day","Migraine is one of the primary headache disorders with a high prevalence worldwide, leading to significant disability and reduced quality of life. Trigeminal nerve activation and alterations in central pain processing mechanisms play a crucial role in the pathophysiology of migraine. Recent studies suggest that migraine may not only be a headache disorder but also a systemic pain disorder associated with changes in central pain processing mechanisms. Central sensitization is defined as increased sensitivity of nociceptive neurons in the central nervous system to afferent stimuli and is considered a key mechanism in the development and maintenance of chronic pain conditions. This condition is characterized by pain hypersensitivity, allodynia, and generalized pain sensitivity.\n\nIn addition to headaches, other musculoskeletal pains are also frequently reported in migraine patients. Spinal pain, particularly neck and lower back pain, can occur in migraine sufferers, with central sensitization contributing to the condition, considering the spine as a chain. Large population-based studies have shown a significant association between primary headaches and persistent low back pain, and a higher prevalence of concomitant low back pain has been reported in individuals with chronic migraine and chronic tension-type headaches. This association is suggested to be explained by the shared nociceptive pathways of the head and spinal structures and the changes in central pain processing seen in chronic pain conditions.\n\nThis relationship between migraine and musculoskeletal pain is also explained by the presence of shared neuroanatomical structures such as the trigemino-cervical complex. Nociceptive afferents from the upper cervical spine and cranial structures converge at the trigemino-cervical complex level in the brainstem, creating a predisposition to the co-occurrence of head and neck pain. This mechanism suggests that pain or dysfunction in the cervical region in migraine patients may be related to headache symptoms. Studies have shown that neck pain is more common in individuals with migraine than in the general population, and research suggests this rate may be approximately 10-12 times higher compared to healthy individuals. Furthermore, it has been reported that individuals with migraine more frequently experience tenderness in cranio-cervical muscles such as the upper trapezius, sternocleidomastoid, and suboccipital muscles, myofascial trigger points, and increased muscle sensitivity. The literature also emphasizes that these cervical symptoms may be related to migraine frequency, attack severity, and headache-related disability.\n\nThese findings suggest that migraine should be considered not only as a primary headache disorder but also as a complex neurobiological condition associated with widespread pain sensitivity and musculoskeletal symptoms. A better understanding of the relationship between migraine and musculoskeletal pain could be important for developing multidisciplinary treatment approaches. However, clinical studies in the literature that evaluate migraine, accompanying neck pain, and lower back pain together in terms of common pain mechanisms are quite limited. Therefore, the rationale for this study is that examining factors such as central sensitization, pain threshold, pain catastrophizing, psychological factors, body awareness, and regional disability together in migraine patients can lead to a better understanding of the pathophysiology of migraine-related musculoskeletal pain. Based on all these reasons and evidence, the aim of this study is to investigate the possible common pain mechanisms and musculoskeletal pathophysiological processes of migraine-related neck and back pain in migraine patients with accompanying neck and\u002For back pain by evaluating factors such as central sensitization, pain threshold, pain catastrophizing, psychological factors, body awareness, and regional disability together.",[29,555,28],"Migraine",[557,266,296,558,559],"migraine","central sensitization","pain threshold","2026-05-16",{"date":562,"type":41},"2026-05-19",{"date":564,"type":22},"2026-04-30",{"date":299,"type":22},{"name":567,"class":48},"Bozok University",{"id":569,"slug":570,"hasResults":12,"nctId":571,"briefTitle":572,"officialTitle":572,"acronym":573,"eligibilityCriteria":574,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":411,"enrollmentInfo":575,"targetDuration":4,"studyType":23,"phases":576,"briefSummary":577,"conditions":578,"keywords":579,"overallStatus":372,"whyStopped":4,"lastUpdateSubmitDate":584,"lastUpdatePostDateStruct":585,"startDateStruct":587,"completionDateStruct":589,"leadSponsor":591,"locationsCount":4},"100638287","integrated-neuromuscular-inhibition-technique-versus-instrument-assisted-soft-tissue-mobilization-on-neck-disability-endurance-and-proprioception-of-nonspecific-chronic-neck-pain-100638287","NCT07599631","Integrated Neuromuscular Inhibition Technique Versus Instrument-Assisted Soft Tissue Mobilization On Neck Disability, Endurance, and Proprioception Of Nonspecific Chronic Neck Pain","CNP","Inclusion Criteria:\n\n* All participants ages will range from 18 to 50 years.\n* BMI ranged from 18.5 to 30.\n* have TrPs in their UT muscle, pain at rest, a jump sign when pressure is applied, limited range of motion (ROM), and referred pain.\n* The participants will report pain in the posterior or posterior lateral aspect of the neck in the previous 3 months\n\nExclusion Criteria:\n\n* Participants of cervical spine disorders (cervical disc disease, cervical spondylitis, cervical myelopathy.\n* Participants with musculoskeletal conditions.\n* Pregnant women.\n* Participants with congenital postural deformities.\n* Participants who had a definite visual disability.",{"count":363,"type":22},[25],"this study will be conducted to compare INIT versus IASTM on neck disability, cervical muscle endurance and proprioception, cervical alignment, pain intensity, pressure pain threshold in patients with neck pain",[29],[580,581,582,583,420,266],"Integrated Neuromuscular Inhibition Technique","Instrument-Assisted Soft Tissue Mobilization","neck disability","endurance","2026-05-14",{"date":586,"type":41},"2026-05-20",{"date":588,"type":22},"2026-05-25",{"date":590,"type":22},"2027-05-25",{"name":401,"class":48},{"id":593,"slug":594,"hasResults":12,"nctId":595,"briefTitle":596,"officialTitle":597,"acronym":4,"eligibilityCriteria":598,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":599,"enrollmentInfo":600,"targetDuration":552,"studyType":147,"phases":4,"briefSummary":602,"conditions":603,"keywords":606,"overallStatus":372,"whyStopped":4,"lastUpdateSubmitDate":329,"lastUpdatePostDateStruct":609,"startDateStruct":611,"completionDateStruct":613,"leadSponsor":615,"locationsCount":4},"100632243","does-the-cervical-stenosis-affect-hand-function-100632243","NCT07511153","Does the Cervical Stenosis Affect Hand Function?","Does the Degree of Cervical Spinal Stenosis Affect Hand Function?","Inclusion Criteria:\n\n* Individuals aged 18-75\n* Individuals who have previously undergone a cervical MRI\n* Cases where the degree of stenosis can be clearly determined on MRI\n* Individuals who have had neck pain for at least 3 months\n\nExclusion Criteria:\n\n* Individuals who declined to participate in the study\n* Individuals who had undergone cervical surgery\n* Individuals diagnosed with vertigo\n* Individuals with sudden hearing loss\n* Individuals with additional neurological conditions\n* Individuals with psychiatric or cognitive disorders that would prevent measurement in the study","75 Years",{"count":601,"type":22},180,"The cervical spine is a complex structure that supports the weight of the head and protects the spinal cord and nerve roots. Cervical spinal stenosis (CSS), which develops as a result of degenerative processes, can cause narrowing of the spinal canal and compression of nerve structures, leading to symptoms such as pain, numbness, and weakness. This condition can negatively affect hand function, particularly grip strength and dexterity. However, studies in the literature examining the effect of CSS on grip strength and hand function are limited. Therefore, this study will be conducted to determine the effect of the severity of cervical spinal stenosis, identified in patients who underwent MRI following their presentation with cervical problems at the Physical Medicine and Rehabilitation outpatient clinic of Buca Seyfi Demirsoy Training and Research Hospital, İzmir Democracy University, on hand grip strength and functionality. Grip strength will be assessed using the Jamar hand dynamometer, and fine pinch strength will be evaluated using the Lafayette pinch meter. Additionally, hand functionality will be measured using the Nine-Hole Peg Test. The impact of neck pain on daily life will be assessed using the Neck Disability Index. The data obtained will be compared and analyzed using appropriate statistical methods.\n\nThis study is expected to fill a significant gap in the current literature by comprehensively elucidating the effects of cervical stenosis on hand function and grip performance, thereby contributing to the individualization of rehabilitation approaches.",[604,605,29],"Spinal Stenosis Cervical","Hand Grip Strength",[607,608,266],"cervical spinal stenosis","hand grip strength",{"date":610,"type":41},"2026-05-15",{"date":612,"type":22},"2026-09-01",{"date":614,"type":22},"2027-12-01",{"name":616,"class":48},"Izmir Democracy University",{"id":618,"slug":619,"hasResults":12,"nctId":620,"briefTitle":621,"officialTitle":621,"acronym":4,"eligibilityCriteria":622,"healthyVolunteers":12,"sex":18,"minAge":228,"maxAge":174,"enrollmentInfo":623,"targetDuration":4,"studyType":23,"phases":625,"briefSummary":626,"conditions":627,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":628,"lastUpdatePostDateStruct":629,"startDateStruct":630,"completionDateStruct":632,"leadSponsor":634,"locationsCount":49},"100552310","the-effect-of-osteopathic-treatment-on-craniocervico-mandibular-dysfunction-100552310","NCT06471426","The Effect of Osteopathic Treatment on Craniocervico-Mandibular Dysfunction","Inclusion Criteria:\n\n* male and female subjects 19-65 years old\n* neck pain and\u002For headaches of \\> 1 month duration\n\nExclusion Criteria:\n\n* prior cervical or thoracic spinal surgery\n* diagnosis cervical radiculopathy or pinched nerve in the neck\n* diagnosis of jaw disease or dysfunction\n* diagnosis of connective tissue or muscle disorders\n* diagnosis of cancer\n* previous spinal cord injury\n* Inflammatory arthritis and fibromyalgia\n* eye movement disorder\n* known pregnancy (hormonal changes affecting tissues could be a confounding variable)\n* tobacco use\n* known diabetes or prediabetes\n* allergy to ultrasound gel (propylene glycol)\n* history of manual therapy treatment within the past 2 weeks\n* history of injection for pain within the past month\n* currently taking muscle relaxers",{"count":624,"type":22},30,[25],"The goal of this clinical trial is to measure the effects of osteopathic manipulative treatment (OMT) on tissues of the craniocervico-mandibular unit (CCMU) in individuals with neck pain and headaches.\n\nThe main questions to answer are:\n\n1. How does OMT affect CCMU muscle stiffness\n2. How does OMT affect jaw motion\n3. How does OMT affect autonomic function\n4. Is pain pressure threshold affected by OMT of the CCMU\n\nParticipants will undergo the following interventions:\n\n1. Photos taken to measure head and neck angles\n2. Ultrasound\n3. Smooth Pursuit Neck Torsion Test\n4. Motion Capture\n5. Autonomic Protocol\n6. Algometry\n7. Surveys",[345,29],"2026-05-11",{"date":584,"type":41},{"date":631,"type":41},"2024-04-22",{"date":633,"type":22},"2026-09-22",{"name":635,"class":48},"Edward Via Virginia College of Osteopathic Medicine",{"id":637,"slug":638,"hasResults":12,"nctId":639,"briefTitle":640,"officialTitle":641,"acronym":4,"eligibilityCriteria":642,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":643,"enrollmentInfo":644,"targetDuration":4,"studyType":23,"phases":646,"briefSummary":647,"conditions":648,"keywords":650,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":655,"lastUpdatePostDateStruct":656,"startDateStruct":657,"completionDateStruct":659,"leadSponsor":661,"locationsCount":49},"100639677","influence-of-fun-physical-activities-on-neck-pain-and-posture-in-children-100639677","NCT07578766","Influence of Fun Physical Activities on Neck Pain and Posture in Children","Effects of Fun Games Activities on Neck Pain and Posture Among School Going Children","Inclusion Criteria:\n\n* Student with Forward neck posture with angle 48 ° measured with kinovea software.\n* Teenagers (School going age ≤ 15 yrs)\n* Both gender\n* Children with neck pain\n\nExclusion Criteria:\n\n* Children with scoliosis\n* Pain due to frank injuries (like fractures)\n* Patients having had any recent surgical procedure would not be enrolled in this study.","15 Years",{"count":645,"type":22},90,[25],"Neck pain is becoming increasingly common in school-aged children, mainly due to prolonged use of electronic devices and poor posture (especially forward head posture), often referred to as \"text neck syndrome.\" Other contributing factors include sedentary lifestyles, heavy school bags, and rapid growth during adolescence. While this issue has been widely studied in adults and teenagers, research focusing on younger children is limited. This study aims to evaluate the effects of fun-game activities, cervical stretching exercises, and postural education in reducing neck pain and improving posture among school-going children.",[29,649],"Posture Disorders in Children",[266,651,652,653,654],"stretching exercise","posture","schools","child","2026-05-05",{"date":628,"type":41},{"date":658,"type":41},"2026-04-14",{"date":660,"type":22},"2026-07-05",{"name":454,"class":48},{"id":663,"slug":664,"hasResults":12,"nctId":665,"briefTitle":666,"officialTitle":667,"acronym":4,"eligibilityCriteria":668,"healthyVolunteers":12,"sex":18,"minAge":669,"maxAge":670,"enrollmentInfo":671,"targetDuration":4,"studyType":23,"phases":673,"briefSummary":674,"conditions":675,"keywords":676,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":679,"lastUpdatePostDateStruct":680,"startDateStruct":682,"completionDateStruct":684,"leadSponsor":686,"locationsCount":49},"100638578","myofascial-release-and-dynamic-cupping-in-children-100638578","NCT07575139","Myofascial Release and Dynamic Cupping in Children","Comparative Effects of Myofascial Release Therapy and Dynamic Cupping on Neck Pain and Posture in School Going Children.","Inclusion Criteria:\n\n* Children with age 13 to 16.\n* Both boys and girls\n* neck pain (NPRS score from 7 to 10)\n* Presence of postural deviations (will be access by using Plumb line test)\n\nExclusion Criteria:\n\n* Skin infections, open wounds, or dermatological conditions in the neck\u002Fupper back region\n* Neurological symptoms (cerebral palsy, muscular dystrophy, multiple sclerosis)\n* Recent use of analgesics\n* use of assistive devices (collars)","7 Years","12 Years",{"count":672,"type":22},45,[25],"Neck pain is a common musculoskeletal disorder that significantly affects quality of life and daily activities, with an annual prevalence of 30-50% worldwide. This randomized clinical trial aims to compare the effects of myofascial release therapy and dynamic cupping on neck pain and posture in school-based children aged 7-12 years. A total of 40 children with neck pain and postural deviations will be recruited from schools and randomly assigned to either a myofascial release group or a dynamic cupping group (20 participants each) for a 6-week intervention. Children with skin conditions, neurological symptoms, recent analgesic use, or assistive device use will be excluded. Outcomes will be assessed using the Visual Analog Scale, goniometer, and plumb line test, and data will be analyzed using SPSS version 27 to determine the effectiveness of both interventions in reducing pain and improving posture.",[29],[266,652,677,678],"dynamic cupping","myofascial release","2026-05-04",{"date":681,"type":41},"2026-05-08",{"date":683,"type":41},"2025-01-29",{"date":685,"type":22},"2026-08-19",{"name":454,"class":48}]