[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuro-developmental-delay\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuro-developmental-delay":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100646053","pediatric-movement-disorders-of-unknown-etiology-in-vietnam-vpemd-100646053",false,"NCT07695610","Pediatric Movement Disorders of Unknown Etiology in Vietnam (VPeMD)","Phenotypic and Genotypic Characterization of Pediatric Movement Disorders of Unknown Etiology in Vietnam","VPeMD","Inclusion Criteria:\n\n* Children younger than 18 years old.\n* Patients with clinically confirmed movement disorders based on direct examination and\u002For video review by at least two pediatric neurology specialists.\n* Patients with movement disorders of unknown etiology after appropriate neurological evaluation and exclusion of clear acquired causes.\n* Patients evaluated or treated at University Medical Center Ho Chi Minh City or Children's Hospital 1 during the study period.\n* Patients and\u002For legal guardians who provide written informed consent for study participation and genetic testing.\n\nExclusion Criteria:\n\n* Patients with isolated or transient primary tic disorders.\n* Patients with a confirmed acquired cause of movement disorder.\n* Patients or legal guardians who decline participation or withdraw from the study.\n* Patients with insufficient clinical information or unavailable biological samples for genetic analysis.","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","12 Months","OBSERVATIONAL","This observational patient registry aims to describe the clinical phenotypes and genetic findings of Vietnamese children with movement disorders of unknown etiology. Eligible participants are children with clinically confirmed movement disorders after evaluation by pediatric neurology specialists and after exclusion of clear acquired causes.\n\nThe study will collect clinical data, neurological examination findings, available laboratory and imaging results, and video recordings of abnormal movements when consent is provided. Blood samples will be collected for whole-exome sequencing and related genetic analysis. Genetic variants will be classified according to accepted clinical genetics standards and compared with the patients' clinical phenotypes.\n\nThe study is expected to improve understanding of the phenotypic and genotypic spectrum of pediatric movement disorders in Vietnam, support genetic counseling, and evaluate how genetic results may influence diagnosis, follow-up, prognosis, and treatment planning.",[26,27,28],"Movement Disorders in Children","Neuro Developmental Delay","Neurogenetic Disorders",[15,30,31,32],"Vietnam","Whole Exome Sequencing","Pediatric movement disorders","RECRUITING","2026-07-08",{"date":36,"type":37},"2026-07-10","ACTUAL",{"date":39,"type":37},"2026-04-17",{"date":41,"type":21},"2029-01-31",{"name":43,"class":44},"University of Medicine and Pharmacy at Ho Chi Minh City","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100641766","aquatic-therapy-versus-sensory-room-intervention-for-sensory-motor-function-in-children-with-sensory-processing-disorder-100641766","NCT07646951","Aquatic Therapy Versus Sensory Room Intervention for Sensory-Motor Function in Children With Sensory Processing Disorder","Comparative Impact of Aquatic Therapy and Conventional Sensory Room Intervention on Adaptive Neural Responses and Sensory-Motor Praxis in Children With Monochannel Sensory Processing Disorder: A Randomized Clinical Trial","AQUA vs SRI Tr","Inclusion Criteria:\n\n* Children aged 4-8 years with a confirmed diagnosis of monochannel sensory processing disorder.\n\nExclusion Criteria:\n\n* Medical Instability: Any acute illness, fever, or infectious diseases (e.g., ear infections or open wounds) that contraindicate pool therapy.\n* Neurological Risks: Children with uncontrolled seizures or epilepsy that poses a safety risk in an aquatic environment.\n* Severe Phobia: Extreme fear of water (hydrophobia) that prevents active participation in aquatic exercises.\n* Recent Surgery: Any recent surgical interventions (orthopedic or neurological) that have not yet reached full clinical clearance for physical activity.\n* Incontinence: Severe lack of bowel or bladder control unless specific medical swim diapers are utilized according to facility policy.","4 Years","8 Years",{"count":56,"type":21},60,"INTERVENTIONAL",[59],"NA","This randomized clinical trial compares the effects of aquatic therapy and conventional sensory room intervention on adaptive neural responses and sensory-motor praxis in children with Monochannel Sensory Processing Disorder. Participants will be randomly assigned to one of the two intervention groups. Outcomes related to sensory processing, sensory-motor praxis, and adaptive responses will be evaluated before and after treatment. The study aims to determine whether aquatic therapy provides additional benefits compared with conventional sensory room intervention in improving sensory integration and functional performance in affected children.",[27,62],"Sensory Disorders",[64,65],"Aquatic Therapy vs Sensory Room + SPD + Children","sensory disorder - aquatic therapy","NOT_YET_RECRUITING","2026-06-09",{"date":69,"type":37},"2026-06-15",{"date":69,"type":21},{"date":72,"type":21},"2026-12-20",{"name":74,"class":44},"MTI University"]