[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-epileptic-seizures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-epileptic-seizures":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100650489","phase-1-effects-of-a-sigle-dose-of-ayahuasca-in-patients-with-psychogenic-non-epileptic-seizures-an-open-label-clinical-trial-100650489",false,"NCT07747324","Effects of a Sigle Dose of Ayahuasca in Patients With Psychogenic Non-epileptic Seizures: an Open Label Clinical Trial","Inclusion Criteria:\n\n* Patients aged 18 to 60 with documented PNES (confirmed via VEEG), without a diagnosis of comorbid epilepsy, and currently receiving follow-up care at outpatient clinics. To enroll in the study, patients must undergo a gradual reduction and discontinuation of any psychotropic medications (antidepressants, antipsychotics, benzodiazepines, or mood stabilizers\u002Fanticonvulsants) they are currently taking, in order to avoid drug interactions with-or influence on-the effects of ayahuasca.\n\nExclusion Criteria:\n\n* Patients who have not experienced psychogenic seizures in the last 3 months; patients diagnosed with epilepsy; patients who refuse to reduce or discontinue their current psychotropic medications; patients with a history of prior ayahuasca use; patients with a history of substance use disorder; patients who refuse to sign the Informed Consent Form; patients with schizophrenia or other psychotic disorders and\u002For impaired reality testing; and pregnant or breastfeeding women.","ALL","18 Years","60 Years",{"count":19,"type":20},15,"ESTIMATED","INTERVENTIONAL",[23,24],"PHASE1","PHASE2","Open label intervention with a single dose of ayahuasca in patients with psychogenic non-epileptic seizures (PNES)",[27],"Non Epileptic Seizures","RECRUITING","2026-07-30",{"date":31,"type":32},"2026-08-05","ACTUAL",{"date":34,"type":32},"2026-07-01",{"date":36,"type":20},"2027-08-30",{"name":38,"class":39},"University of Sao Paulo","OTHER","Non-epileptic Seizures"]