[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-st-elevation-nstemi-myocardial-infarction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-st-elevation-nstemi-myocardial-infarction":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":36,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":5},"100656422","analysis-of-life-threatening-arrhythmias-after-acute-coronary-syndrome-100656422",false,"NCT07824050","Analysis of Life-threatening ARrhythMias After Acute Coronary Syndrome","Current Relevance of Malignant Cardiac Arrhythmia in Patients Admitted for Acute Coronary Syndrome","ALARM-ACS","Inclusion criteria Patients\n\n* Aged 18 years or older\n* With acute coronary syndrome (ST-elevation myocardial infarction, non-ST-elevation myocardial infarction, and unstable angina pectoris) or out-of-hospital cardiac arrest (OHCA) due to ACS\n* Admitted to the emergency cardiac care unit, emergency department, coronary care unit (CCU), intensive care unit (ICU), or cardiology ward.\n\nExclusion criteria\n\n\\- Patients who have indicated that their data may not be used for scientific research or for improving the quality of care.","ALL","18 Years",{"count":20,"type":21},2775,"ESTIMATED","7 Days","OBSERVATIONAL","Patients admitted with an acute coronary syndrome (ACS) are at increased risk of malignant cardiac arrhythmias (MA), such as sustained ventricular tachycardia and ventricular fibrillation. Therefore, patients with ST-elevation myocardial infarction (STEMI) are continuously monitored for a minimum of 24 hours after onset symptoms. Longer monitoring is advised in patients at intermediate to high risk of cardiac arrhythmias, however this risk stratification is not evidence based. Hospitalization, particularly in STEMI patients, is advised for a minimum of 48-72 hours.\n\nAMI care requires a substantial commitment of bed capacity and staff, resulting in high healthcare costs.\n\nIn patients who have undergone acute PCI (such as STEMI patients or NSTEMI patients with persistent symptoms), monitoring is primarily aimed at early recognition of MA and signs of persistent or recurrent ischaemia after the intervention.\n\nIn NSTEMI\u002FUAP patients still awaiting invasive treatment, the emphasis lies on detecting increasing ischaemia in the as-yet untreated coronary vessel, as well as identifying arrhythmias that may arise as a result.\n\nThe true incidence of MA cannot be precisely established due to heterogeneity in the literature, and moreover varies between patients with ST-elevation myocardial infarction, non-ST-elevation myocardial infarction, and unstable angina pectoris, owing to differences in disease process and care pathway.\n\nA better understanding of the current incidence and risk of MA in patients with ACS may contribute to optimizing the monitoring of this patient group, thereby enabling more efficient use of hospital beds and healthcare staff. This prospective quality registry therefore aims to establish the current incidence of MA in ACS patients and to identify potential predictors of MA, while also taking into account other acute complications such as asystole and pulseless electrical activity (PEA).",[26,27,28,29,30,31,32,33,34,35],"Acute Coronary Syndromes (ACS)","Ventricular Tachycardia (VT)","Ventricular Fibrillation","Pulseless Electrical Activity","Asystole","Cardiac Arrest (CA)","Myocardial Infarction (MI)","Non-ST Elevation (NSTEMI) Myocardial Infarction","ST Elevation (STEMI) Myocardial Infarction","Unstable Angina (UA)",[37,38,39,40,41,28,42,43,44],"Incidence","predictors","timing","in-hospital complication","Ventricular Tachycardia","Cardiac Arrest","acute myocardial infarction","acute coronary syndrome","RECRUITING","2026-10-07",{"date":48,"type":49},"2026-10-13","ACTUAL",{"date":51,"type":49},"2026-07-14",{"date":53,"type":21},"2029-04-01",{"name":55,"class":56},"Catharina Ziekenhuis Eindhoven","OTHER"]