[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obese-individuals\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obese-individuals":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100659618","post-exercise-blood-pressure-with-inorganic-nitrate-100659618",false,"NCT07869472","Post-exercise Blood Pressure With Inorganic Nitrate","Effects of Inorganic Nitrate Supplementation on Post-exercise Hypotension Response Following Acute Exercise in Young Adults With Elevated Body Mass Index and Blood Pressure","BEET-DOWN","Inclusion Criteria:\n\n* Willingness and ability to comply with scheduled visits and study procedures.\n* Males and females, ages 18-40 years old\n* Sedentary (\\\u003C150 minutes of moderate intensity aerobic exercise per week, or not engaged in a regular exercise program at all\n* Resting systolic BP ≥ 120 mmHg.\n* BMI ≥ 30 kg\u002Fm2\n* Waist circumference ≥94 cm for males and ≥80 cm for females\n* Be able to perform exercise on a cycle ergometer without assistance\n* Stable medication regimen for the last 6 months\n* Be able to discontinue the use of inorganic nitrate rich foods such as beets, arugula, spinach, celery, and grapefruit throughout the duration of the study.\n\nExclusion Criteria:\n\n* Body mass index ≤ 29.9 Kg\u002Fm2\n* Smoker within last 5 years\n* Has experienced significant weight loss \\~3 kg in the last three months or taking any weight loss drugs\n* Current medical condition that prohibits exercising at high intensities\n* Currently on hormone replacement of any kind\n* History of medical conditions that would prohibit high intensity exercise, such as:, uncontrolled hypertension (≥140\u002F90), diabetes, myocardial infarction, cerebrovascular event, known cardiovascular, pulmonary, renal, metabolic diseases, and acute or unstable disease other than high BMI and waist circumference\n* Current injuries that would prohibit exercising on a stationary bike\n* Currently restricted by medical doctor to engage in exercise\n* Currently taking or have taken any of the following medications in the last 4 weeks (calcium channel blockers, statins, ACE or renin inhibitors, angiotensin receptor blockers, organic nitrates (e.g., nitroglycerine, alpha- or beta-blockers, diuretics, proton pump inhibitors, PDE-5 inhibitors (e.g., Cialis, Viagra), or xanthine oxidase inhibitors (e.g., Allopurinol))\n* Oral antibiotic use within previous four weeks including over-the-counter antibacterial mouthwash or a mouthwash containing chlorhexidine and unwilling to discontinue use\n* Oral cancer\u002Fsevere oral disease\n* Had hysterectomy or oophorectomy\n* Pregnant women or planning to be pregnant, Fetuses, neonates, children, prisoners, cognitively impaired, non-English speaking participants",true,"ALL","18 Years","40 Years",{"count":22,"type":23},12,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise alone.",[29,30],"Obese Individuals","Central Adiposity",[32,33,34,35],"obesity","central adiposity","elevated blood pressure","dietary nitrate","NOT_YET_RECRUITING","2026-10-06",{"date":39,"type":40},"2026-10-09","ACTUAL",{"date":42,"type":23},"2026-10-15",{"date":44,"type":23},"2027-03-30",{"name":46,"class":47},"University of Virginia","OTHER"]