[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oral-health-related-quality-of-life-ohrqol\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oral-health-related-quality-of-life-ohrqol":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100652402","new-functional-ingredient-for-oral-care-100652402",false,"NCT07771907","New Functional Ingredient for Oral Care","Inclusion Criteria:\n\n* Healthy Adults\n\nExclusion Criteria:\n\n* Women who are pregnant, breastfeeding, or planning to become pregnant during the study period\n* Known allergy or hypersensitivity to any of the study materials or ingredients\n* Current smokers or individuals who have used tobacco products (including smokeless tobacco) within the last 6 months\n* Antibiotic use within 3 months of study start\n* Current use of key drugs - Systemic Anti-inflammatory Drugs, Immunosuppressants, and Drugs known to cause Xerostomia\n* Current use of anti-gingivitis products Presence of extensive fixed or removable prosthodontic appliances or less than 50% of natural teeth\n* History of diagnosed periodontal disease requiring treatment, including active periodontal disease, extensive untreated caries, or significant oral lesions\n* History of chronic systemic diseases including: cardiovascular disease, uncontrolled diabetes, autoimmune diseases, HIV, and Hepatitis B or C\n* Concurrent participation in another clinical study.",true,"ALL","18 Years","65 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to find new ingredients for oral care products that can improve gum health. We want to learn if new botanical blends can help reduce gum inflammation, strengthen the gum's natural barrier, and lessen dry mouth symptoms. This study will also look at how these ingredients affect the helpful bacteria in the mouth (oral microbiome) and overall oral health.\n\nResearchers will compare different botanical blends against a control group that uses a simple mouthwash without the active ingredients to see their effects.\n\nParticipants will use a simple mouthwash daily for 14 days. This mouthwash will contain either one of two botanical ingredients, a combination of both, or no active ingredient (a control). During the study participants will complete questionnaires about their quality of life and any dry mouth symptoms at home and provide samples of saliva and fluid from their gums at different times during the study to check for changes in their oral microbiome and inflammation levels.",[27],"Oral Health Related Quality of Life (OHRQoL)",[29,30,31,32],"Gingivitis","Xerostomia","Oral Microbiome","Oral Health-Related Quality of Life","NOT_YET_RECRUITING","2026-08-17",{"date":36,"type":37},"2026-08-19","ACTUAL",{"date":39,"type":21},"2026-09",{"date":41,"type":21},"2027-03",{"name":43,"class":44},"Access Business Group","INDUSTRY",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":45},"100647939","orofacial-pain-and-oral-health-related-quality-of-life-in-musicians-in-german-amateur-orchestras-100647939","NCT07714837","Orofacial Pain and Oral Health-Related Quality of Life in Musicians in German Amateur Orchestras","Orofacial Pain, Sleep-Related Problems, and Oral Health-Related Quality of Life Among Musicians in German Amateur Orchestras: A Cross-Sectional Online Survey","OSQ-MUS","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Active membership in a German amateur orchestra\n* Consent to study participation (given by completing the questionnaire)\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Missing \u002F declined consent to participate",{"count":55,"type":21},400,"OBSERVATIONAL","This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras. Participants complete a single, anonymous, approximately 10-minute questionnaire covering demographic data, orofacial pain, sleep bruxism, perceived stress, sleep quality, and the German short version of the Oral Health Impact Profile (OHIP-14). The study examines whether these outcomes differ between instrument groups (woodwind, brass, string, percussion, and other instruments). The primary hypothesis is that players of wind instruments (woodwind and brass) more frequently report orofacial pain and experience a different OHRQoL than players of other instrument groups. The study has a pilot character and aims to generate data to inform future research and targeted dental care concepts for this population.",[59,60,27],"Orofacial Pain","Sleep Bruxism",[62,63,64,65,66,67,68,69],"amateur musicians","orchestra","wind instruments","brass","woodwind","orofacial pain","sleep bruxism","oral health-related quality of life","2026-07-14",{"date":72,"type":37},"2026-07-20",{"date":74,"type":21},"2026-09-01",{"date":76,"type":21},"2026-11-01",{"name":78,"class":79},"University Medical Center Goettingen","OTHER",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":89,"conditions":90,"keywords":100,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":45},"100629572","oral-health-dento-facial-condition-and-ohrqol-in-subjects-with-mowat-wilson-syndrome-an-epidemiologic-study-100629572","NCT07476417","Oral Health, Dento-facial Condition and OHRQoL in Subjects With Mowat-Wilson Syndrome: an Epidemiologic Study.","ORALMOWAT26","Inclusion Criteria:\n\n* individuals affected by MWS with confirmed molecularly diagnosis of ZEB2 gene variation.\n* written informed consent statement signed by parents\u002Flegal guardians for participation in the study\n\nExclusion Criteria:\n\n* individuals not affected by MWS\n* refusal of parents\u002Flegal guardians to participate in the study",{"count":88,"type":21},25,"Mowat-Wilson Syndrome (MWS) is a rare syndrome characterized by the presence of facial gestalt and delayed psychomotor development, variably associated with intellectual disability, epilepsy, Hirschsprung's disease (HSCR) and multiple congenital malformations.\n\nAlthough there is evidence of the presence of dental and craniofacial anomalies in MWS, little epidemiological data is available to date.\n\nThe goal of this observational study is to assess oral health and dento-facial phenotype of people affected by Mowat-Wilson Syndrome (MWS). In addition, the Oral Health Related Quality of Life (OHRQoL) will be investigated.",[91,92,93,94,95,96,97,27,98,99],"Mowat-Wilson Syndrome","Dental Caries","Periodontal Diseases","Sleep Related Breathing Disorder","Tooth Diseases","Malocclusion","Tooth Abnormalities","Craniofacial Abnormalities","Oral Mucosal Disease",[101,102,103,104,105,98],"Mowat-Wilson syndrome","dental caries","periodontal diseases","malocclusion","oral health","2026-03-19",{"date":108,"type":37},"2026-03-24",{"date":110,"type":21},"2026-04-01",{"date":112,"type":21},"2026-08-30",{"name":114,"class":79},"University of Milan"]