[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"organophosphate-poisoning\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:organophosphate-poisoning":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100652722","magnesium-sulphate-with-atropine-and-pralidoxime-vs-standard-therapy-alone-in-acute-organophosphate-poisoning-100652722",false,"NCT07777835","Magnesium Sulphate With Atropine and Pralidoxime vs Standard Therapy Alone in Acute Organophosphate Poisoning","Comparison of the Efficacy of Adjunctive Magnesium Sulphate With Standard Atropine and Pralidoxime Therapy vs Standard Therapy Alone in Acute Organophosphate Poisoning","Inclusion Criteria:\n\n* Both genders\n* Adult patients aged between 18 and 50 years\n* Confirmed clinical diagnosis of organophosphate poisoning containing insecticide, through the oral route\n* Adult patients, or their legally authorized representative, who will provide informed consent to participate in the study\n\nExclusion Criteria:\n\n* Patients with known allergy to MgSO4\n* Patients with documented pre-existing renal impairment (Serum creatinine more than 1.5mg\u002Fdl)\n* Patients with documented pre-existing cardiac impairments (e.g., heart block)\n* Pregnant or lactating women\n* Confirmed intake of any other drug or poison\n* Patients who will be declared dead on arrival or those who expired within 2 hours of presentation","ALL","18 Years","50 Years",{"count":20,"type":21},38,"ESTIMATED","INTERVENTIONAL",[24],"NA","Pakistan, being a developing country, is one of the regions with the most cases of organophosphate (OP) poisoning\u002Ftoxicity. MgSO4 is one of the most promising adjunctive treatments that needs to be tested. This study is being carried out with the objective of comparing the 15-day all-cause mortality rate and the total cumulative atropine requirement during hospitalization between patients receiving adjunctive magnesium sulphate with standard therapy and those receiving standard therapy alone.",[27],"Organophosphate Poisoning","RECRUITING","2026-08-17",{"date":31,"type":32},"2026-08-20","ACTUAL",{"date":34,"type":32},"2026-05-10",{"date":36,"type":21},"2026-10-10",{"name":38,"class":39},"Muhammad Aamir Latif","OTHER"]