[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ovarian-reserve-markers\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ovarian-reserve-markers":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100652335","ovarian-stromal-stiffness-and-ovarian-reserve-parameters-via-transvaginal-shear-wave-elastography-100652335",false,"NCT07773337","Ovarian Stromal Stiffness and Ovarian Reserve Parameters Via Transvaginal Shear Wave Elastography","Relationship Between Ovarian Stromal Stiffness Measured by Transvaginal Shear Wave Elastography and Hormonal and Ultrasonographic Ovarian Function Parameters","Inclusion Criteria:\n\n* Female patients aged 18 to 45 years.\n* Regular menstrual cycles (21-35 days) or irregular menstruel cycles (oligo-anovaltion)\n* Normal pelvic anatomy on baseline ultrasound evaluation.\n* Written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* History of prior ovarian or adnexal surgery.\n* History of pelvic radiotherapy or chemotherapy.\n* Presence of structural pelvic\u002Fovarian pathology (e.g., endometrioma, ovarian cyst, dermoid cyst, active pelvic inflammatory disease).\n* Use of hormonal contraceptives, ovulation induction agents, or hormone therapy within the last 3 months.\n* Pregnancy or current lactation.\n* Severe obesity or technical limitations preventing adequate transvaginal ultrasound and elastography imaging",true,"FEMALE","18 Years","45 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to evaluate the relationship between ovarian stromal stiffness measured by transvaginal shear wave elastography (SWE) and conventional hormonal and ultrasonographic parameters of ovarian reserve. Reproductive-aged female patients will be evaluated to determine whether tissue elasticity provided by SWE correlates with ovarian function markers such as anti-Müllerian hormone (AMH), antral follicle count (AFC), and ovarian volume.",[28,29,30,31],"Ovarian Reserve Markers","Ovarian Function","Infertility","Anovulatory",[33,34,35,36],"Shear Wave Elastography","Transvaginal Ultrasound","Ovarian Stroma","Anti-Mullerian Hormone","NOT_YET_RECRUITING","2026-08-18",{"date":40,"type":41},"2026-08-20","ACTUAL",{"date":43,"type":22},"2026-08",{"date":45,"type":22},"2026-12-01",{"name":47,"class":48},"Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":58,"enrollmentInfo":59,"targetDuration":61,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100564215","fertility-and-ovarian-reserve-in-female-childhood-cancer-survivors-100564215","NCT06626282","Fertility and Ovarian Reserve in Female Childhood Cancer Survivors","PReserving Fertility and Quality of Life IN Belgian Female Paediatric CancEr SurvivorS","PRINCESS","Inclusion Criteria:\n\n* Child and adolescent female patients included in the Paediatrics Late Effects Project:\n* diagnosed with cancer1 between 01\u002F01\u002F2004 and 31\u002F12\u002F2018\n* \\\u003C17 years old at diagnosis\n* treated at CHU Liège site Citadelle or CHC, Cliniques Universitaires Saint-Luc and HUDERF\n* alive\n* ≥ 18 years-old at time of recruitment.\n\nExclusion Criteria:\n\n* Cancer diagnosis for controls","50 Years",{"count":60,"type":22},340,"3 Months","OBSERVATIONAL","Ovarian function impairment affects the quality of life of the survivors of paediatric cancer by impacting fertility, bone quality and mental and cognitive health. The objective of this project is to evaluate the impact of low-intermediate dose alkylating agents associated or not with ovarian cryopreservation technique on ovarian function in female survivors of paediatric cancer. We propose to identify new epigenetic markers in order to predict the risk of premature ovarian insufficiency. The project will be led by a national multi-disciplinary team (paediatric oncologists, gynaecologists, endocrinologists). Paediatric cancer clinical data (therapy, fertility preservation, ...) will be extracted from the Paediatrics Late Effects database and additional data will be collected during PRINCESS fertility evaluation. Through translational and multi-disciplinary approaches, results should improve quality of life and fertility preservation in female survivors of paediatric cancer by developing new personalised screening tools for premature ovarian insufficiency.",[65,66,67,68,28,69,70,71],"Childhood Cancer Survivors","Fertility","Ovarian Reserve","CED","Cryopreservation","Alkylating Agents","Female","RECRUITING","2024-10-30",{"date":75,"type":41},"2024-11-01",{"date":77,"type":41},"2024-10-09",{"date":79,"type":22},"2028-12-31",{"name":81,"class":48},"Centre Hospitalier Universitaire de Liege",3]