[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"overweight-adolescents\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:overweight-adolescents":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,54,82,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":36,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100652837","lean-beef-as-part-of-a-healthy-meal-plan-in-adolescents-with-polycystic-ovary-syndrome-pcospolyendocrine-metabolic-ovarian-syndrome-pmos-100652837",false,"NCT07780188","Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)\u002FPolyendocrine Metabolic Ovarian Syndrome (PMOS)","Effect of Increasing Lean Beef Intake as Part of a Healthy Meal Plan on Glycemic Control in Adolescents With Polycystic Ovary Syndrome (PCOS)\u002FPolyendocrine Metabolic Ovarian Syndrome (PMOS)","Beef+","Inclusion Criteria:\n\n* Female Adolescent\n* 11-17 years old\n* Suspected or confirmed diagnosis of PCOS\n* ≥1-year post-menarche\n* BMI ≥85th percentile for age\u002Fheight\n* Able to read and speak English\n\nExclusion Criteria:\n\n* Medications affecting glucoregulation, metabolic health, and\u002For appetite (e.g., metformin, GLP-1)\n* Unable or unwilling to eat beef\n* Pregnant or planning pregnancy during study\n* HbA1c ≥6.5%\n* Unwilling or unable to complete study procedures\n* Conditions affecting ability to complete study procedures or the intervention such as gastrointestinal diseases or syndromes, bleeding disorders, ongoing or unresolved eating disorder)\n* Conditions affecting reproductive function other than PCOS\n* Conditions that may interfere with continuous glucose monitor (CGM) application or use, including dermatological conditions such as eczema or allergies\u002Freactions to medical adhesives\n\nConditional Exclusion Criteria:\n\n\\- Current use of hormonal contraceptives if in the suspected PCOS group (allowable if current for at least the previous 3 months with physician-confirmed PCOS)","FEMALE","11 Years","17 Years",{"count":21,"type":22},36,"ESTIMATED","INTERVENTIONAL",[25],"NA","This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)\u002FPolyendocrine Metabolic Ovarian Syndrome (PMOS) to evaluate the effectiveness and feasibility of a tailored dietary intervention which will be termed \"Beef+\", that will emphasize the incorporation of unprocessed, lean beef (\\\u003C10% fat) as part of a healthy meal plan to improve glycemic control, diet quality, and health-related quality of life",[28,29,30,31,32,33,34,35],"PCOS (Polycystic Ovary Syndrome)","Obese Adolescents","Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities","Overweight Adolescents","Irregular Menstrual Cycle","Irregular Menstrual Cycles","Hirsutism","Hyperandrogenism",[37,38,39,40],"Dietary Intervention","Polycystic Ovary Syndrome (PCOS)","Adolescents","Randomized Control Trial","RECRUITING","2026-08-19",{"date":44,"type":45},"2026-08-21","ACTUAL",{"date":47,"type":22},"2026-09-01",{"date":49,"type":22},"2028-04-30",{"name":51,"class":52},"Texas A&M University","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":23,"phases":67,"briefSummary":68,"conditions":69,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100637708","improving-sleep-health-and-circadian-timing-to-support-cardiometabolic-health-in-adolescents-100637708","NCT07618117","Improving Sleep Health and Circadian Timing to Support Cardiometabolic Health in Adolescents","Mitigating Cardiometabolic Risk by Improving Sleep Health and Circadian Timing in Adolescents With Overweight\u002FObesity","REST","Inclusion Criteria:\n\n1. High school students between 14-19 years\n2. Overweight\u002Fobesity (BMI \\>85% for age and sex)\n3. Have habitually insufficient sleep, defined as ≤ 7 hours per night on school days\n4. Habitually inactive (≤ 3 h of physical activity reported per week)\n5. Tanner stage 4 or 5, based on breast development for girls and testicular size for boys.\n\nExclusion Criteria:\n\n1. Reported diagnosis of sleep disorder (e.g., insomnia, obstructive sleep apnea)\n2. Medical comorbidities that impact sleep or insulin sensitivity (e.g., diabetes \\[based on history or screening HbA1c\\])\n3. Regular use of medications affecting sleep or insulin sensitivity (e.g., stimulants, sleep aids, systemic steroids, insulin sensitizers, GLP-1 agonists)\n4. IQ\\\u003C70 or severe mental illness that may impact sleep or study participation (e.g., schizophrenia), eating disorder, or active suicidal ideation\n5. Schedules that would preclude participants from adhering to the sleep schedules (e.g., night-shift employment)","ALL","14 Years","19 Years",{"count":66,"type":22},60,[25],"Many teenagers get too little and late timed sleep. High body weight and diabetes are increasing in teenagers as well. This study plans to learn more about whether improving sleep habits can help improve how the body regulates blood sugar and energy use in teenagers who have higher body weight. To answer this question, the investigators plan to enroll teenagers who get \\\u003C7 hours of sleep on school nights and measure changes in blood sugars and energy use after two weeks of typical sleep (sleeping on their normal school schedule) and two weeks of a sleep intervention that includes spending longer time in bed at night, melatonin, and morning light.",[31,70,71],"Sleep","Insulin Sensitivity","NOT_YET_RECRUITING","2026-05-26",{"date":75,"type":45},"2026-06-01",{"date":77,"type":22},"2026-08-25",{"date":79,"type":22},"2030-08-30",{"name":81,"class":52},"University of Colorado, Denver",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":62,"minAge":18,"maxAge":63,"enrollmentInfo":89,"targetDuration":4,"studyType":23,"phases":91,"briefSummary":94,"conditions":95,"keywords":96,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":53},"100574172","phase-1-pilot-testing-a-novel-approach-to-pediatric-obesity-treatment-100574172","NCT06755827","Pilot Testing a Novel Approach to Pediatric Obesity Treatment","Emotion Regulation Intervention to Improve Neural Responsiveness and Health","Inclusion Criteria:\n\n* Being English-proficient\n* Ages 11-14\n* At or above the 85th BMI percentile based on age and sex norms\n* Having access to WIFI or cellular data to attend the telehealth groups\n* Living in a home in Lubbock County (TX) or surrounding areas.\n\nExclusion Criteria:\n\n* Having a psychiatric or medical diagnosis that interferes with participation (e.g., significant developmental delay; pregnancy)\n* Current enrollment in overweight\u002Fobesity treatment.\n* Because the study will include entering an MRI scanner, additional standard exclusion criteria will be considered (e.g., having immovable medical devices with batteries, body piercings on the head\u002Fface, and having substantial visual impairment that cannot be corrected with staff-provided glasses)",{"count":90,"type":22},30,[92,93],"PHASE1","PHASE2","The goal of this clinical trial is to learn if an emotion regulation and self-monitoring intervention can help treat overweight and obesity in teens. The main question it aims to answer is:\n\n* Does emotion regulation and self-monitoring help reduce biases in teens with overweight and obesity?\n* Do changes in biases relate to changes in health functioning and health behavior?\n\nResearchers will compare the intervention to the provision of educational handouts about overweight and obesity to see if the intervention is more effective.\n\nParticipants will:\n\n* Complete self-report questionnaires, an fMRI scan, and have their blood drawn\n* Received educational handouts or attend weekly telehealth group sessions weekly for four weeks and be asked to self-monitor their mood and behavior between sessions\n* Return to complete the same questionnaires, fMRI and blood draw procedures",[31,29],[97,98,99,100,101],"overweight","obesity","adolescents","neuronal responsiveness","emotion regulation","2026-05-13",{"date":104,"type":45},"2026-05-15",{"date":106,"type":45},"2026-03-24",{"date":108,"type":22},"2026-12-31",{"name":110,"class":52},"Texas Tech University",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":117,"sex":62,"minAge":18,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":23,"phases":121,"briefSummary":122,"conditions":123,"keywords":125,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":141},"100618519","building-healthy-food-environment-in-schools-evaluating-co-created-interventions-in-low-resource-settings-betternutrition4adolescent-100618519","NCT07332676","Building Healthy Food Environment in Schools: Evaluating Co-created Interventions in Low Resource Settings. #BetterNutrition4Adolescent","Inclusion Criteria:\n\n* Adolescents studying in grade 7 to 9 (aged 11-15 years) Exclusion criteria:\n\nExclusion Criteria:\n\n* Adolescents with siblings enrolled in schools assigned to a different trial arm to avoid clustering, with underlying medical conditions and those who plan to change school within one year of enrollment (during follow up period) will be excluded.",true,"15 Years",{"count":120,"type":22},2600,[25],"The goal of this clinical trial is to learn if a multicomponent nutrition program developed together with the students, parents, teachers and canteen operators will improve nutrition status of adolescents. It will also learn about the acceptability and feasibility of implementing the program in the school settings. The main questions it aims to answer are:\n\nWhat is the effect of co-created multicomponent intervention promoting healthy food behavior and environment in schools on the proportion of normal weight adolescents? What proportion of the target adolescents and teachers does the intervention reach? What proportion of the schools are willing to implement the intervention? What was the level of fidelity of implementation of all components of the intervention and the barriers and facilitators to implementation? What is the cost for maintenance, and facilitators and barriers of sustainment? School going adolescents studying in grades 7 to 9 from 26 schools in India and 26 schools in Nepal will be enrolled in the trial and their height, weight, dietary behavior, mental well-being and physical activity will be measured at baseline and at 12 months follow up. After the baseline assessment the school community (students, school environment, parents, teachers, canteen operators) will receive the intervention.",[31,124,29],"Underweight",[126,127,128,129,130,131],"nutrition","multicomponent nutrition intervention","co-creation","adolescent","low resource settings","Poor nutrition","2025-12-30",{"date":134,"type":45},"2026-01-12",{"date":136,"type":22},"2026-10",{"date":138,"type":22},"2027-12",{"name":140,"class":52},"Norwegian University of Science and Technology",2]