[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pain-anticipation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pain-anticipation":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100612269","muscle-synergies-in-pain-and-pain-anticipation-100612269",false,"NCT07251387","Muscle Synergies in Pain and Pain Anticipation","Test-retest Fidelity of a Tool for Calculation of Muscle Synergies","Inclusion Criteria:\n\n* Aged 18-35 years old\n* Healthy participant with no self-reported diagnosed neurological, musculoskeletal, or cardiovascular disorders\n* Body Mass Index (BMI) \\\u003C 30\n* Ability to walk unaided for at least 10 minutes without major physical limitations\n\nExclusion Criteria:\n\n* Presence of pain at the time of testing\n* Self-reported diagnosed condition affecting mobility\n* Known allergy to any component of the study cream\n* Allergy to EMG electrode adhesives\n* Inability to stand unassisted for more than 1 minute\n* Inability to walk\u002Frun at the required speed and distance\n* Weight exceeding 150 kg (due to treadmill limitations)\n* Recent intake (prior intervention) of:\n* Analgesics (within 6 hours)\n* Cigarettes (within 6 hours)\n* Caffeine (within 2 hours)\n* Skin lesions at the cream application site\n* Pregnancy\n* Failure to understand instructions\n* Daytime pain reported by participant on day of experimentation",true,"ALL","18 Years","35 Years",{"count":21,"type":22},12,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study investigates how the anticipation of pain affects muscle synergies. One group will be recruited who will first experience actual pain from capsaicin cream and are then presented with a harmless cream deceptively labeled as capsaicin. The changes in muscle synergies will be measured during walking tasks.",[28,29,30],"Pain","Nocebo Effect","Pain Anticipation",[32,33,28,34,35,36],"Nocebo effect","Pain anticipation","Gait","Motricity","Muscle synergies","RECRUITING","2026-06-08",{"date":40,"type":41},"2026-06-11","ACTUAL",{"date":43,"type":41},"2026-01-01",{"date":45,"type":22},"2027-10-01",{"name":47,"class":48},"Universite de Picardie Jules Verne","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":65,"startDateStruct":66,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},"100587528","muscular-synergies-and-behavioral-adaptations-of-gait-in-pain-anticipation-syamapp-100587528","NCT06929559","Muscular Synergies and Behavioral Adaptations of Gait in Pain Anticipation (SYAMAPP)","SYAMAPP","Inclusion Criteria:\n\n* Aged 18-35 years\n* Healthy participant with no self-reported diagnosed neurological, musculoskeletal, or cardiovascular disorders\n* Body Mass Index (BMI) \\\u003C 30\n* Ability to walk unaided for at least 10 minutes without major physical limitations\n\nExclusion Criteria:\n\n* Presence of pain at the time of testing\n* Self-reported diagnosed condition affecting mobility\n* Known allergy to any component of the study cream\n* Allergy to EMG electrode adhesives\n* Inability to stand unassisted for more than 1 minute\n* Inability to walk\u002Frun at the required speed and distance\n* Weight exceeding 150 kg (due to treadmill limitations)\n* Recent intake of:\n* Analgesics (within 6 hours)\n* Cigarettes (within 6 hours)\n* Caffeine (within 2 hours)\n* Skin lesions at the cream application site\n* Pregnancy\n* Failure to understand instructions\n* Daytime pain reported by participant on day of experimentation",{"count":57,"type":22},34,[25],"The purpose of this study is to determine whether the anticipation of pain influences gait control and psychophysiological responses in healthy individuals. Participants will receive a neutral cream described either as potentially painful (experimental group) or inert (control group), and their behavioral and physiological adaptations will be measured during walking tasks.",[29,30],[32,33,62,35,34,63,64,36],"Pain expectation","Walking","Healthy",{"date":40,"type":41},{"date":43,"type":41},{"date":68,"type":22},"2028-10-30",{"name":47,"class":48},1]