[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pain-during-caries-excavation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pain-during-caries-excavation":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100659624","comparison-of-intraoperative-pain-perception-during-caries-excavation-using-smart-burs-and-carisolv-to-conventional-diamond-burs-100659624",false,"NCT07869407","Comparison of Intraoperative Pain Perception During Caries Excavation Using Smart Burs and Carisolv to Conventional Diamond Burs","Inclusion Criteria:\n\n* Be male or female.\n* Be 18-45 years of age.\n* Have at least one active carious lesion with exposed dentin in an asymptomatic mandibular molar.\n* Have an ICDAS II Code 5 lesion: a dentinal cavity clearly visible clinically, with the cavity surface feeling soft or leathery on gentle probing.\n* Have a radiograph showing a clear band of dentin between the carious lesion and the pulp.\n* Provide written informed consent to participate.\n\nExclusion Criteria:\n\n* Symptoms\u002Fsigns of pulpitis.\n* Pulp exposure.\n* Abscess formation, including swelling, redness, or a fistula adjacent to the affected tooth.\n* Necrotic pulp, indicated by lack of response to cold testing.\n* Cardiovascular disease.\n* Diabetes mellitus.\n* Hypertension.\n* Severe periodontal disease.\n* Pregnancy.\n* Unwillingness or inability to provide informed consent\u002Fparticipate.","ALL","18 Years","45 Years",{"count":19,"type":20},66,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this randomized controlled trial is to compare the amount of pain experienced during removal of dental caries using Smart burs, Carisolv, and conventional diamond burs in adults aged 18-45 years with active caries in asymptomatic mandibular molars.\n\nThe main questions it aims to answer are:\n\nDoes the method used for caries removal affect the amount of pain experienced?\n\nIs there a difference in pain perception between Smart burs, Carisolv, and conventional diamond burs?\n\nResearchers will compare the three treatment groups to see whether pain perception during caries excavation differs between the methods.\n\nParticipants will:\n\nBe randomly assigned to one of three groups: Smart burs, Carisolv, or conventional diamond burs.\n\nUndergo caries removal using the assigned method.\n\nRate their pain during the procedure using a 0-10 Visual Analogue Scale (VAS).",[26],"Pain During Caries Excavation",[28,29,30,31,32,33,34,35,36,37,38],"Dental Caries","Caries excavation","Intraoperative pain","Pain perception","Smart polymer burs","Carisolv","Diamond burs","Minimally invasive dentistry","Chemomechanical caries removal","Operative dentistry","Caries removal techniques","RECRUITING","2026-10-07",{"date":42,"type":43},"2026-10-09","ACTUAL",{"date":45,"type":43},"2026-07-01",{"date":47,"type":20},"2027-01-30",{"name":49,"class":50},"Rehman Medical Institute - RMI","OTHER"]