[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pain-from-onabotulinumtoxina-injections\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pain-from-onabotulinumtoxina-injections":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":5},"100636915","topical-intranasal-anesthetic-block-for-reducing-the-pain-of-botulinum-toxin-injections-for-chronic-migraine-100636915",false,"NCT07571889","Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Injections for Chronic Migraine","Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Injections for Chronic Migraine: A Randomized, Double-Blind, Placebo-Controlled Crossover Pilot Study","Inclusion Criteria:\n\n* Aged ≥18 years\n* Any gender\n* Able to provide informed consent\n* Meets clinical criteria for onabotulinumtoxinA for chronic migraine (minimum of 2 days of disability per month due to facial or headache pain, or 8 headache days per month, or more than 15 headaches per month)\n* Scheduled for modified PREEMPT injections at the clinical site\n\nExclusion Criteria:\n\n* Aged \\\u003C 18 years\n* Trigeminal neuralgia, cluster headache, or other primary headache disorders as dominant diagnosis\n* Not able to provide informed consent\n* Known allergy\u002Fhypersensitivity to lidocaine or amide anesthetics\n* Pregnancy\u002Flactation\n* Inability to tolerate intranasal nasal cotton pledgets\n* Significant nasal pathology at placement site","ALL","18 Years",{"count":19,"type":20},18,"ESTIMATED","INTERVENTIONAL",[23],"NA","People find the injections used in onabotulinumtoxinA (Botox®) uncomfortable. This study will test whether putting a small piece of cotton soaked with 4% lidocaine (a numbing medicine) inside the front of each nostril for 5 minutes before the injections reduces injection pain compared with cotton soaked in saline (salt water).",[26],"Pain From onabotulinumtoxinA Injections","RECRUITING","2026-05-04",{"date":30,"type":31},"2026-05-06","ACTUAL",{"date":33,"type":31},"2026-03-03",{"date":35,"type":20},"2027-01",{"name":37,"class":38},"Association of Migraine Disorders","OTHER"]