[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pain-in-bone-metastases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pain-in-bone-metastases":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100649113","phase-1-a-phase-ib-randomized-double-blind-placebo-controlled-study-to-evaluate-the-safety-and-efficacy-of-vc004-capsules-for-pain-in-bone-metastases-100649113",false,"NCT07731685","A Phase Ib, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of VC004 Capsules for Pain in Bone Metastases","Inclusion Criteria:\n\n1. Participants must understand and voluntarily sign the informed consent form (ICF);\n2. Male or female, aged ≥ 18 years;\n3. Eastern Cooperative Oncology Group (ECOG) performance status score of 0 to 2;\n4. Life expectancy of ≥ 12 weeks, as assessed by the investigator;\n5. The participant is able to communicate well with the investigator, and is willing and able to comply with all scheduled visits, treatment plans, laboratory tests, and other study procedures.\n\nExclusion Criteria:\n\n1. The participant's pain is associated with oncologic emergencies, such as intestinal obstruction\u002Fperforation, spinal cord compression, epidural metastasis, or fracture or impending fracture of weight-bearing bones;\n2. The participant has known or suspected unstable brain metastases or leptomeningeal metastases；\n3. History of severe alcohol, analgesic, or narcotic drug abuse within 6 months prior to screening;\n4. Major surgery within 3 months prior to screening, or planned major surgery during the study period;\n5. Female participants who are planning to become pregnant, are pregnant, or are breastfeeding; or participants who are unwilling or unable to use effective contraception throughout the entire study period and for 3 months after the end of the study;\n6. Any other condition that, in the opinion of the investigator, would make the participant unsuitable for participation in this study.","ALL","18 Years",{"count":18,"type":19},26,"ESTIMATED","INTERVENTIONAL",[22],"PHASE1","This is a randomized, double-blind, placebo-controlled Phase Ib study evaluating the safety and efficacy of VC004 capsules for the relief of moderate-to-severe pain associated with bone metastases",[25],"Pain in Bone Metastases","NOT_YET_RECRUITING","2026-07-23",{"date":29,"type":30},"2026-07-28","ACTUAL",{"date":32,"type":19},"2026-07-30",{"date":34,"type":19},"2027-12-30",{"name":36,"class":37},"Jiangsu vcare pharmaceutical technology co., LTD","INDUSTRY",2]