[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pain-postoperative-arthroscopy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pain-postoperative-arthroscopy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":20,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100649170","ultrasonographic-predictors-of-adductor-canal-block-effectiveness-in-total-knee-arthroplasty-100649170",false,"NCT07730216","Ultrasonographic Predictors of Adductor Canal Block Effectiveness in Total Knee Arthroplasty","Inclusion Criteria:\n\n* Age ≥18 years\n* Scheduled for elective primary unilateral total knee arthroplasty under spinal anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-III\n\nExclusion Criteria:\n\n* Daily opioid use or chronic pain syndrome\n* Diabetic or other clinically diagnosed peripheral neuropathy\n* Coagulopathy\n* Infection at the injection site\n* Known allergy or hypersensitivity to local anesthetics\n* Revision total knee arthroplasty\n* Conversion from spinal anesthesia to general anesthesia during surgery\n* General anesthesia as the planned anesthetic technique","ALL","18 Years",{"count":18,"type":19},623,"ESTIMATED","12 Months","OBSERVATIONAL","Total knee arthroplasty (TKA) is associated with substantial postoperative pain and opioid requirements, making effective multimodal analgesia essential for early mobilization, functional recovery, and reduction of opioid-related adverse events \\[1,2\\]. Adductor canal block (ACB) has become a key component of enhanced recovery after surgery (ERAS) protocols because it provides effective anterior knee analgesia while largely preserving quadriceps muscle strength \\[2-4\\]. However, analgesic efficacy after ACB remains variable, and some patients require rescue opioid analgesia despite technically successful block placement \\[5\\]. Although ultrasound guidance improves block accuracy, factors such as tissue depth, anatomical variations, saphenous nerve visibility, and injectate spread pattern may influence clinical outcomes \\[6,7\\]. Prospective evidence regarding the predictive value of these ultrasound-derived parameters for ACB analgesic failure remains limited. Therefore, this study aims to evaluate whether preoperative ultrasound-derived tissue and target parameters-including skin-to-target depth, subcutaneous fat thickness, muscle thickness, saphenous nerve visibility, and injectate spread pattern-can predict ACB analgesic failure and early postoperative analgesic outcomes following TKA.",[24,25,26],"Arthroplasty, Replacement, Knee","Nerve Block Assessment","Pain, Postoperative Arthroscopy",[28,29,30,31],"Adductor Canal Block","Total Knee Arthroplasty","Ultrasound","Postoperative Analgesia","RECRUITING","2026-08-09",{"date":35,"type":36},"2026-08-12","ACTUAL",{"date":33,"type":36},{"date":39,"type":19},"2027-07-13",{"name":41,"class":42},"Konya City Hospital","OTHER"]