[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"partial-edentulism-class-3\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:partial-edentulism-class-3":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100647847","internal-irrigation-surgery-100647847",false,"NCT07715825","Internal Irrigation Surgery","Evaluation of an Internal Irrigation Surgical Guide to Reduce Heat Generation During Dental Implant Surgery","Inclusion Criteria:\n\n1. Patients aged 25+\n2. Patients requiring a dental implant in the maxilla or mandible\n3. Patients with sufficient bone volume for implant placement.\n4. Patients classified as ASA I or II based on the American Society of Anesthesiologists (ASA) physical status classification system.\n5. Patients capable of providing informed consent and willing to adhere to study procedures and follow-up appointments.\n6. Patients with adequate interarch space to accommodate guided implant surgery.\n7. No history of implant placement at the experimental or control site.\n\nExclusion Criteria:\n\n1. ASA class 3 or higher\n2. Currently undergoing or history of bisphosphonate or antiresorptive therapy\n3. Patients who have received prior radiation therapy to the head and neck.\n4. Patients with contraindications for implant placement, such as active infections or severe periodontal disease.\n5. Pregnant or breastfeeding\n6. Patients with psychiatric or cognitive conditions impairing informed consent or compliance",true,"ALL","25 Years","75 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","Heat generated during osteotomy and implant placement may cause thermal injury to bone and adversely affect healing and osseointegration. External irrigation is commonly used to reduce heat generation; however, cooling may be less effective at the drill-bone interface, particularly during guided implant surgery.\n\nSurgical guides with integrated irrigation channels have been developed to deliver coolant more directly to the osteotomy site, but clinical evidence regarding their effectiveness remains limited. This study will evaluate whether an internal irrigation surgical guide system reduces heat generation during osteotomy compared with a conventional guided implant surgery approach. The study will also assess clinical outcomes associated with implant placement. The findings may help inform safer and more effective protocols for guided dental implant surgery.",[28,29,30,31],"Dental Implant Healing","Partial Edentulism Class 1","Partial Edentulism Class II","Partial Edentulism Class 3",[33,34],"dental implant surgery","dental implant placement","NOT_YET_RECRUITING","2026-08-03",{"date":38,"type":39},"2026-08-06","ACTUAL",{"date":41,"type":22},"2026-09-01",{"date":43,"type":22},"2028-12-31",{"name":45,"class":46},"University of Maryland, Baltimore","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":16,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100559678","compare-cadcam-metallic-rpd-to-conventional-metallic-rpd-in-terms-of-oral-health-related-quality-of-life-100559678","NCT06567262","Compare CAD\u002FCAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life","Oral Health Related Quality of Life and Cost Effectiveness in CAD\u002FCAM and Conventional Metallic Partial Denture Frameworks in Mandibular Kennedy Class III Cases: A Randomised Cross-over Trial","Inclusion Criteria:\n\n1. Patients with unilateral bounded saddles in the mandible (Kennedy class III).\n2. Opposing dentition is fully intact or restored.\n3. Sufficient inter-arch space.\n4. Angle's class I maxilla-mandibular relationship.\n\nExclusion Criteria:\n\n1. Periodontal affection of the abutment teeth.\n2. Skeletal mal-relation.\n3. Unmotivated patients to maintain adequate oral hygiene to follow up.\n4. Patients with neuromuscular and Psychiatric disorders.\n5. Systematic disease affecting bone and periodontal health.\n6. Insufficient inter-arch space.\n7. Patients with physical reasons that could affect follow up.","18 Years",{"count":57,"type":22},19,[25],"Patients will be randomised to receive CAD\u002FCAM metallic removable partial denture (RPD) followed by Conventional metallic RPD (Group A), or the opposite sequence (Group B), with a 3-month wear duration for each denture and washout period for one week. Patients will be recalled at base line and 3 months following prosthetic insertion to evaluate Oral health related quality of life. It is hypothesized that removable partial dentures with CAD\u002FCAM metallic RPD frameworks would improve Oral health related quality of life than those with Conventional metallic RPD frameworks.",[31],"2024-08-23",{"date":63,"type":39},"2024-08-26",{"date":65,"type":22},"2024-10",{"date":67,"type":22},"2025-03",{"name":69,"class":46},"Cairo University"]