[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"partially-edentulous-mandible\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:partially-edentulous-mandible":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,82],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100641450","evaluation-of-occlusal-contact-distribution-in-digitally-fabricated-implant-retained-fixed-partial-dentures-in-mandibular-kennedy-class-ii-patients-following-artificial-intelligence-bite-optimization-a-quasi-experimental-study-100641450",false,"NCT07657910","Evaluation of Occlusal Contact Distribution in Digitally Fabricated Implant-Retained Fixed Partial Dentures in Mandibular Kennedy Class II Patients Following Artificial Intelligence Bite Optimization: A Quasi-Experimental Study","Quasi","Inclusion Criteria:\n\n1. Patients with a unilateral mandibular distal extension area (Kennedy Class II partially edentulous mandibular arch) and who are indicated for the insertion of 2 implants.\n2. Fully dentate opposing maxillary arch or restored with a suitable, well constructed fixed prosthesis.\n3. The remaining teeth should be in good periodontal health, with no signs of inflammation or movement.\n4. The edentulous area should be covered by a healthy, firm mucoperiosteum, with no or minimal tissue undercut.\n5. Patient should be with class I occlusion.\n6. No occlusal disorder; stable jaw relation.\n7. No TMD signs or symptoms.\n8. Patients should be in generally good health and free of systemic conditions that can affect the implant treatment, such as diabetes mellitus.\n\nExclusion Criteria:\n\n1. Patients with psychological or mental disorders.\n2. Patients with insufficient interarch space.\n3. Patients with parafunctional habits, such as bruxism.\n4. After the healing phase and exactly before the prosthetic phase, if the inserted implants showed any signs of peri-implantitis or aggressive crestal bone resorption, then this case will be excluded and replaced with another case.",true,"ALL","18 Years",{"count":20,"type":21},15,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of the study is to evaluate the occlusal contact distribution in digitally fabricated implant-retained fixed partial dentures in mandibular Kennedy Class II patients before and after artificial intelligence bite optimization.",[27],"Partially Edentulous Mandible",[29,30,31,32,33,34,35],"Kennedy Class II","mandible","Bite optimization","implant","3shape","Artificial intelligence","Occlusal contact","NOT_YET_RECRUITING","2026-06-14",{"date":39,"type":40},"2026-06-18","ACTUAL",{"date":42,"type":21},"2026-06",{"date":44,"type":21},"2026-09",{"name":46,"class":47},"Cairo University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":62,"conditions":63,"keywords":64,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":48},"100633217","phase-4-artificial-intelligence-assisted-workflow-versus-conventional-workflow-in-guided-implant-placement-100633217","NCT07523815","Artificial Intelligence Assisted Workflow Versus Conventional Workflow in Guided Implant Placement","Assessment of the Accuracy of Artificial Intelligence Assisted Workflow Versus Conventional Workflow in Computer Guided Implant Placement: A Randomized Controlled Clinical Trial.","Implant","Inclusion Criteria:\n\n* Kennedy class III partially edentulous patient with or without modifications.\n* Patients who need single implant posterior site delayed implant placement.\n* Patients above 18 and below 60 years of age.\n* Natural healthy neighboring teeth without need of new restorations.\n\nExclusion Criteria:\n\n* Patients with D4 bone density.\n* Patients with known systemic or local diseases or treatments which can affect normal tissue healing.\n* Patients who are heavy smokers.\n* Presence of signs of active infection or pus formation.\n* Patients with a need for implants in the anterior region.\n* Additional oral surgery in the region of interest.\n* Need For Bone grafting.\n* Pregnant and\u002For lactating women","50 Years",{"count":59,"type":21},20,[61],"PHASE4","The AI assisted CAD\u002FCAM workflow will be adopted for the treatment planning and guide design generation with the aim of comparing precision of implant placement with conventional digital workflow.",[27],[65,66,67,68,69,70,71],"Dental Implant","Implant Placement","Accuracy","Computer guided","CAIS","Implant planning","CAD\u002FCAM","RECRUITING","2026-04-06",{"date":75,"type":40},"2026-04-13",{"date":77,"type":21},"2026-05-01",{"date":79,"type":21},"2026-12-01",{"name":81,"class":47},"Sandra Moussa Botros El Tarzi",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":4},"100551439","peri-implant-bone-formation-of-grafted-sites-around-hydrophilic-and-non-hydrophilic-dental-implants-100551439","NCT06460103","Peri-implant Bone Formation of Grafted Sites Around Hydrophilic and Non-hydrophilic Dental Implants","Effect of Implant Surface Hydrophilicity on Peri-Implant Bone Formation Around Simultaneously Grafted Transiently Placed Titanium Zirconium Dental Small Diameter Implants - A Randomized Controlled Human Histometric Clinical Trial","Inclusion Criteria:\n\n* Patient age ≥ 18 years\n* Patients with a diagnosed indication for single tooth extraction and scheduled for consented replacement by an implant-based restoration requiring prior bone augmentation\n* Only patients displaying periodontally healthy teeth adjacent to the extracted teeth shall be included (probing depth (PD) \\\u003C 4mm, no bleeding on probing (BOP)\n* Patients must be physically and psychologically able to undergo implant surgery and restorative procedures (American Academy of Anesthesiologist class I or II)\n\nExclusion Criteria:\n\n* Presence of any general contra-indication related to implant therapy\n* Heavy smokers ( ≥10 cigarettes\u002Fday)\n* Patients displaying a history of uncontrolled metabolic disorders (e.g. diabetes mellitus)\n* Patients with a history of malignancy, radiotherapy, or chemotherapy\n* Pregnant or breast feeding patients\n* Patients with a history of immunodeficiencies\n* Patients displaying any metabolic bone disease\n* Patients with disturbed bone or wound healing\n* Patients with untreated or active periodontitis (BOP and PD\\>5mm)\n* Extraction sites displaying an absent or defections buccal bone plate\n* Vulnerable patients will be excluded from the study.",{"count":90,"type":21},70,[24],"Although bone grafting at the same time as the placement of dental implants is a common procedure in implantology, there are currently no data on the influence of different types of implant surfaces on bone healing, which is crucial for implant stability.\n\nThe primary objective of this study is to assess if implant surface properties, i.e. hydrophilicity, affect the osseointegration of the implant in simultaneously augmented bone.\n\nThe secondary objective is to assess if implant surface properties, i.e. surface hydrophilicity, may affect the quantity of newly formed bone in the implant in simultaneously augmented bone.\n\nSurface hydrophilicity modification is a well-adapted concept in dental implantology and is clinically well-established.\n\nIn this prospective study, all participants will receive a bone graft after extraction. After randomization, one group will receive a provisional SLA surface implant and another group will receive a provisional SLActive surface implant. The same standard surgical procedure will be performed for both groups when the definitive implant will be placed.\n\nThe study will run for a total of 3 year, and 35 patients per group will be included.\n\nThe Straumann SLA and SLActive implants, Maxgraft allograft and collprotect collagen membranes used in this study are all approved products on the Swiss market.",[94,27],"Partially Edentulous Maxilla",[96,97,98],"Dental implants","SLActive","Hydrophile surface","2024-06-10",{"date":101,"type":40},"2024-06-14",{"date":103,"type":21},"2024-07",{"date":105,"type":21},"2027-12",{"name":107,"class":47},"University Hospital, Geneva"]