[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"patellar-femoral-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:patellar-femoral-syndrome":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100659602","effectiveness-of-selected-traditional-chinese-medicine-topical-agents-on-long-distance-runner-versus-exercise-therapy-as-control-for-patellofemoral-pain-syndrome-100659602",false,"NCT07865169","Effectiveness of Selected Traditional Chinese Medicine Topical Agents on Long Distance Runner Versus Exercise Therapy as Control for Patellofemoral Pain Syndrome","外敷中藥(吳氏處方)治療長跑手膝痛的臨床研究 Effectiveness of Selected Traditional Chinese Medicine Topical Agents on Long Distance Runner Versus Exercise Therapy as Control for Patellofemoral Pain Syndrome","Inclusion Criteria:\n\n* Mean running distance \\> 20 km\u002Fweek and 10 km\u002Fsession. If kilometer per week conflicted with kilometers per session, for example, 40 km\u002Fweek with a frequency of 5 times\u002Fweek, it is classified according to kilometers per week.\n* Clinical diagnosis of Alzheimer's Disease\n* Be between 18 and 60 years of age and able to provide written informed consent.\n* Have experienced knee pain for more than four weeks.\n* Have no history of external medical interventions, physical therapy, or lower limb surgery for PFPS within the past six weeks, and no acupuncture treatment on knee within the past month.\n\nExclusion Criteria:\n\n* Presence of absolute contraindications for Chinese herbal medicated plasters;\n* Pregnancy or lactation;\n* Oral or topical use of non-steroidal anti-inflammatory drugs within the past two weeks;\n* Steroid injections within the past two months;\n* Clinical, radiographic, or MRI evidence of meniscal or other intra-articular lesions, cruciate ligament or collateral ligament injury or laxity;\n* Concurrent conditions including diabetes, goiter, coagulation disorders, hepatic or renal failure, chronic obstructive pulmonary disease, cardiac disease, neurological disorders, psychiatric disorders, acute or chronic infections, or malignancies;\n* Presence of redness, swelling, burning sensation, pain, infection, or ulceration around the patellar;\n* History of knee surgery, patellar dislocation, fracture (local or at the hip joint), ankle or hip joint injury, meniscus or ligament injury;\n* Lower limb tendinitis, low back pain, sacroiliac joint pain, or any neurological or cardiovascular disease;\n* Presence of rheumatic disease, septic arthritis, osteoarthritis, Osgood-Schlatter disease, or Chondro-Larsen-Johansson syndrome; or clinical assessment indicating significant knee effusion, pronounced hip or lumbar pain (potentially causing referred knee pain), or impairment in performing prescribed exercises; or recurrent patellar subluxation or dislocation;\n* Presence of patella folding syndrome or deep vein thrombosis;\n* Presence of joint fibrosis;\n* Presence of tumors;","ALL","18 Years","60 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","Background: With the rising popularity of long-distance running in Hong Kong, running-related injuries have become more common, particularly patellofemoral pain syndrome (PFPS), which is one of the most prevalent conditions among endurance runners. PFPS can negatively affect training consistency, race performance, and long-term participation. While exercise therapy is the primary intervention, patient adherence and long-term outcomes remain limited. Traditional Chinese Medicine ointment (TCMO, Ng's formula) has shown anti-inflammatory and tissue-repairing properties, making it a promising adjunct therapy for PFPS.\n\nObjective:\n\n1. To evaluate the efficacy and safety of selected topical agents used in Traditional Chinese Medicine on PFPS in long-distance runners.\n2. To assess the impact of these topical agents on running performance in PFPS patients.\n\nMethods: A randomized, controlled, parallel-group, single-blinded trial will be conducted with 50 participants. Group A will receive TCMO combined with exercise therapy, while Group B will receive exercise therapy alone. The intervention lasts four weeks, with weekly follow-ups to monitor adherence. Primary outcomes include Kujala Scale (AKPS), eccentric step-down test, and fastest finishing time of recorded race distances. Safety will be monitored through participant reports and exclusion of individuals with contraindications.",[27,28],"Patellar Femoral Syndrome","TCMO (Ng's Prescription)","NOT_YET_RECRUITING","2026-10-02",{"date":32,"type":33},"2026-10-08","ACTUAL",{"date":35,"type":21},"2026-09-15",{"date":37,"type":21},"2026-12-31",{"name":39,"class":40},"Hong Kong Baptist University","OTHER"]