[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"patello-femoral-pain-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:patello-femoral-pain-syndrome":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,40,76,104,132],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100647523","femoral-nerve-gliding-versus-lumbopelvic-manipulation-in-management-of-patellofemoral-pain-syndrome-100647523",false,"NCT07712146","Femoral Nerve Gliding Versus Lumbopelvic Manipulation in Management of Patellofemoral Pain Syndrome","Inclusion Criteria:\n\n* Age of the subjects is between 18-35 years.\n* BMI will be from 18.5 to ≤ 29.5 Kg\u002Fm2\n* Anterior or retro patellar knee pain either on the dominant or non- dominant leg for at least 6 weeks duration .\n* Worst pain level in the previous month of up to 3cm on a 10cm numerical rating scale (NRS)\n* Per or retropatellar pain during at least 2 of the following activities: squatting, prolonged sitting, kneeling, running, jumping and climbing stairs\n* Showing 2 or more positive signs on the following clinical tests: Clarke's sign, Waldron test, active patellar grind test, patellar compression test, and palpation of the medial\u002Flateral articular border of the patella .\n* Patients had positive femoral slump test with limited active lumber ROM.\n\nExclusion Criteria:\n\n* History of previous knee surgery and any knee pathology (meniscus tear, patellar tendinopathy, ligament sprain and osteoarthritis) .\n* Any systemic diseases and\u002For connective tissue disorders .\n* Bursitis and ligament tears .\n* Lower back dysfunction such as disc lesion, sciatica or spondylolisthesis.\n* participants that had undergone physiotherapy during the preceding 3 month.\n* Pregnant women.\n* Osteoporosis or recent fracture of the hip or spinal joints.• . Radiographic evidence or medical diagnosis of spinal instability (Grade II spondylolithesis or greater), spondyloarthritides, or severe spinal misalignment\n* Nervous system disease or disorder\n* .Lumbosacral nerve root compression (any of the following signs present) a. Positive straight leg raise (SLR) test less than 45°, marked paresis (\\\u003C3\u002F5 on manual muscle testing) involving a major muscle group of the lower extremity, diminished, and asymmetric (lower than uninvolved side), lower extremity muscle stretch reflex and diminished or absent sensation to pinprick in any lower extremity dermatome (D'Agati M 2022).","ALL","18 Years","35 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","The present study is the first one to compare the effectiveness of adding (FNG) versus (LPM ) to conventional exercise therapy in pain, knee functional abilities, hip extension ROM and femoral nerve electrophysiological studies among those with PFPS.\n\nThis study will be conducted at the outpatient clinic of faculty of Physical Therapy, Cairo University Sixty patients with unilateral PFPS referred from an orthopaedic surgeon for selection criteria, will be included in the study. Measurement procedures, treatment procedures, and the study's goal will be explained to each patient before participation in the study. After being informed about the study aim, they will be asked to sign an informed consent for their approval to participate\n\nThe study patients will be randomly assigned into three groups\n\n* Group A: control group will receive conventional hip-knee focused exercises only.\n* Group B: study group will receive FNG in addition to the same conventional hip-knee focused exercises.\n* Group C: study group will receive LPM in addition to the same hip-knee focused exercises All patients will receive 2 sessions\u002Fweek for 6 weeks (12 sessions). They will be instructed to do the conventional hip-knee exercises at least two times per day. Each session will last for 20-30 minutes.\n\nPatients diagnosed with unilateral PFPS will be screened based on the following inclusion and exclusion criteria A sample size of 60 participants will be appropriate. The computations will done using G\\* Power version 3.1.9.2 (Franz Faul, Uni Kiel, Germany) Randomization and blinding will be accomplished through using selected types such as A 1:1:1 allocation ratio will be employed for randomization using the website http:\u002F\u002Fwww.randomization.com. Blinding will be done on the patients, assessor, and statistician. All patients will be blinded to the task assigned to their group by ensuring they will be unaware of the exercises that the other group will complete. To maintain blinding, the intervention sessions will be administered to each member of the treatment group separately. Before the trial began, an impartial research assistant who will not participating in the study and he will keep the allocation sequence a secret. It will be kept hidden in opaque, sealed envelopes that will not be opened until baseline data will be collected\n\nOutcome Measures:\n\n1. Knee Pain\n2. Knee function\n3. Electro-physiological studies including (sensory nerve conduction velocity and distal latency).\n4. Sagittal plane hip extension range of motion as a reference for femoral nerve mechanosensitivity changes - The outcomes will be measured at baseline (pre-test) and after 12sessions (after 6 weeks) (post-test) Then patients will receive 4 types of assessments step's including pain assessment using NRS then knee function assessment using arabic version of AKPS then hip extension ROM assessment using digital goniometer after that the electrophysiological studies including femoral nerve will be conducted using the computerized electromyography device for measuring selective parameters such nerve conduction velocity and its amplitude along with onset and peak latency.\n\nThen Intervention will be completed as follow : All patients will receive two treatment session per week for six weeks (6 sessions), supervised by primary investigator. Separate sessions will be given to each treatment group's members. Each session lasted for 15-30 minutes. The three groups will receive hip-knee focused exercises approved by the clinical practice guidelines linked to the international classification of functioning, disability, and health from the Academy of Orthopedic Physical Therapy of the American Physical Therapy Association which consisted of hamstring\u002Fcalf and ilio-tibial band stretching and hip\u002Fknee strengthening exercises. group B will receive FNG addition to hip-knee focused exercises. group C will receive LPM in addition to hip-knee focused exercise. The session of the control group will start with stretching exercises followed by strengthening exercises. On the other hand, the study group session will start with stretching exercises followed by femoral nerve glide and\u002For LPM then strengthening ex.\n\nThe study has a 3 null hypothesis\n\n1. There will be no statistically significant effects of adding FNG to conventional exercises in patients with PFPS on:\n\n   A) Knee pain. B) Functional abilities. C) Hip extension ROM. D) Electrophysiological study (NCV and distal latency).\n2. There will be no statistically significant effects of adding LPM to conventional exercises in patients with PFPS on:\n\n   A) Knee pain. B) Functional abilities. C) Hip extension ROM. D) Electrophysiological study (NCV and distal latency).\n3. There will be no statistically significant difference between adding FNG versus LPM to conventional exercises in patients with PFPS on:\n\nA) Knee pain. B) Functional abilities.C) Hip extension ROM. D) Electrophysiological study (NCV and distal latency).",[26],"Patello Femoral Pain Syndrome","NOT_YET_RECRUITING","2026-07-16",{"date":30,"type":31},"2026-07-17","ACTUAL",{"date":33,"type":20},"2026-07-01",{"date":35,"type":20},"2027-04-01",{"name":37,"class":38},"Marihan Aziz Zakaria","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":52,"conditions":53,"keywords":59,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":39},"100644562","effects-of-kinesio-taping-versus-mcconnell-taping-on-clinical-outcomes-in-patients-with-patellofemoral-pain-syndrome-100644562","NCT07671482","Effects of Kinesio Taping Versus McConnell Taping on Clinical Outcomes in Patients With Patellofemoral Pain Syndrome.","Effects of Kinesio Taping Versus McConnell Taping on Clinical Outcomes in Patients With Patellofemoral Pain Syndrome. A Randomized Clinical Trial.","PFPS","Inclusion Criteria:\n\n* Anterior or retropatellar pain for a minimum of 3 months during functional activities.\n* 18-50 years of age.\n* Minimum pain of 3\u002F10 on the VAS score.\n* No LL physical therapy in the past 3 months.\n\nExclusion Criteria:\n\n* Meniscal or ligamentous injury\n* Neurological or systemic conditions affecting proprioception, coordination and balance.\n* Spinal referred pain or rheumatoid arthritis.\n* Hip and ankle disorders.","50 Years",{"count":50,"type":20},80,[23],"The primary goal of this randomized clinical trial (RCT) is to evaluate whether Kinesio Taping versus McConnell Taping, when integrated into a standardized hip-knee strengthening and neuromuscular control program, produces significant effects in individuals aged 18-50 with patellofemoral pain syndrome (PFPS).\n\nThe main question it aims to answer is: Does Kinesio Taping compared with McConnell Taping when both combined with a standardized hip-knee exercise program, produce different effects on quadriceps neuromuscular activation (VMO-VL sEMG), pain, functional knee pain, and dynamic knee valgus over a 6 week period intervention?\n\nParticipants will be divided into three groups for comparison: the control group will receive a structured hip-knee physical therapy exercise program without any taping intervention, Kinesio Taping group with a standardized exercise program, and a McConnell Taping group with a standardized exercise program.",[26,54,46,55,56,57,58],"Anterior Knee Pain Syndrome","Patellofemoral Pain Syndrome","Patellofemoral Disorder","Patellofemoral Pain, PFP","Patellofemoral Pain (PFPS)",[60,61,62,63,64,55,65],"Electromyography","EMG","Kinesio Taping","McConnell Taping","Exercise Therapy","Single-Leg Squat","RECRUITING","2026-06-25",{"date":69,"type":31},"2026-06-26",{"date":71,"type":20},"2026-06",{"date":73,"type":20},"2026-10",{"name":75,"class":38},"Cairo University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":21,"phases":87,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":39},"100637264","comparative-effects-of-blood-flow-restriction-resistance-training-versus-blood-flow-restriction-cycling-on-pain-quadriceps-strength-and-functional-outcomes-in-athletes-with-patellofemoral-pain-100637264","NCT07585305","Comparative Effects of Blood Flow Restriction Resistance Training Versus Blood Flow Restriction Cycling on Pain, Quadriceps Strength, and Functional Outcomes in Athletes With Patellofemoral Pain","Comparative Effects of Blood Flow Restriction Resistance Training Versus Blood Flow Restriction Cycling on Pain, Quadriceps Strength, and Functional Outcomes in Athletes With Patellofemoral Pain: A Randomized Controlled Trial","BFR-PFP-RCT","Inclusion Criteria:\n\n1. Male and female athletes aged 18-40 years\n2. Clinically diagnosed with patellofemoral pain syndrome\n3. Anterior or retropatellar knee pain of at least 3 months duration\n4. Pain provoked by at least two functional activities (e.g., squatting, stair climbing, running, prolonged sitting)\n5. Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n1. History of knee surgery or significant knee trauma in the past 6 months\n2. Presence of ligament, meniscal, or cartilage injuries\n3. Neurological, vascular, or systemic inflammatory conditions\n4. Contraindications to BFR training (e.g., deep vein thrombosis, uncontrolled hypertension)\n5. Pregnancy","40 Years",{"count":86,"type":20},48,[23],"This randomized controlled trial compares blood flow restriction (BFR) resistance training (leg press and seated knee extension at 30% 1RM) versus BFR cycling (stationary cycling at low resistance) in 60 athletes (aged 18-40 years) diagnosed with patellofemoral pain syndrome. Both interventions are delivered over 8 weeks (3 sessions\u002Fweek) with a pneumatic cuff set at 80% limb occlusion pressure. Primary outcomes include pain intensity (NPRS), quadriceps strength (handheld dynamometer), and functional ability (Kujala Anterior Knee Pain Scale), assessed at baseline and post-intervention.",[26],[91,92,93,94,95],"Patellofemoral pain","Blood flow restriction training","Quadriceps strength","Athletic Performance","resistance training","2026-06-23",{"date":69,"type":31},{"date":99,"type":31},"2026-05-10",{"date":101,"type":20},"2026-07-25",{"name":103,"class":38},"Ibadat International University, Islamabad",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":111,"sex":15,"minAge":16,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":115,"phases":4,"briefSummary":116,"conditions":117,"keywords":120,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":130,"locationsCount":39},"100625646","ultrasound-examination-of-the-vmo-in-patellofemoral-pain-syndrome-100625646","NCT07425340","Ultrasound Examination of the VMO in Patellofemoral Pain Syndrome","Ultrasonography Examination of the Vastus Medialis Obliquus and Vastus Medialis Longus Muscles in Patellofemoral Pain Syndrome","Inclusion Criteria:\n\n* Between the ages of 18 and 65\n* Have had localized pain in the front of the knee for at least the past 3 months\n* Experience pain during activities that require stair climbing, squatting, prolonged sitting, or knee flexion\n* Have been diagnosed with patellofemoral pain syndrome based on clinical evaluation\n* Volunteer to participate in the study and sign the informed consent form\n\nExclusion Criteria:\n\n* History of previous surgery on the knee joint\n* History of significant trauma to the knee region within the last 6 months\n* Diagnosis of meniscus, ligament injuries, knee osteoarthritis, or inflammatory rheumatic disease\n* Neurological diseases or systemic diseases affecting the musculoskeletal system\n* Presence of other lower extremity pathologies causing pain at a level that could affect measurements",true,"65 Years",{"count":114,"type":20},40,"OBSERVATIONAL","The aim of this study is to examine in detail the ultrasonographic characteristics of the vastus medialis obliquus and vastus medialis longus muscles in individuals with patellofemoral pain syndrome and to compare these findings with those of healthy individuals. It is anticipated that the results obtained will contribute to a better understanding of the muscle-based mechanisms of PFAS and provide a scientific basis for the development of muscle-specific assessment and intervention strategies in physical therapy and rehabilitation practices.",[118,119,26],"Vastus Medialis","Ultrasonographic",[121,122,123],"Patellofemoral Pain","Vastus Medialis Obliqus","Ultrasonographic measurement","2026-02-13",{"date":126,"type":31},"2026-02-20",{"date":128,"type":20},"2026-02-25",{"date":67,"type":20},{"name":131,"class":38},"Hasan Kalyoncu University",{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":138,"eligibilityCriteria":139,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":84,"enrollmentInfo":140,"targetDuration":4,"studyType":21,"phases":141,"briefSummary":142,"conditions":143,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":152},"100624084","ai-driven-ex-versus-conventional-in-pfps-100624084","NCT07405034","AI Driven EX Versus Conventional in PFPS","Artificial Intelligence Driven Exercises Versus Conventional Exercises Therapy for Patellofemoral","AI- PFPS","Inclusion Criteria:\n\n* Their ages range from 18- 40 years old, including both genders (male \\& female).\n* Their BMI will be ≤ 29 kg\u002Fm2.\n* A traumatic knee pain persisting for at least three months.\n\nExclusion Criteria:\n\n* Any congenital deformity of the lower limb,\n* Any recent injuries and surgeries\n* severe foot deformities such as hallux valgus and claw toe\n* Neuromuscular and neurological disorders.- history of patellofemoral dislocation, subluxation .",{"count":114,"type":20},[23],"This study aims to investigate and compare the effect of AI driven exercises program versus the conventional exercises therapy program on pain, function and dynamic knee valgus angle in treatment of patellofemoral pain syndrome.This study is randomized controlled trial and includes 40 participants .These participants divided into 2 groups (A, B), each group will be assessed with 3 measurments (vas ,dynamic knee valgus, Kujala Anterior Knee Pain Scale) and each group will receive difeerent treatments.\n\nThe individuals in group A(study group) will preceive AI driven exercises program while the individual in group B will receive conventional exercises therapy program. Participants in the both groups are prescribed a 6-week comprehensive exercises program (3 sessions per week) day after day and assessment procedure will be performed pre and post treatmeant .",[26],"2026-02-09",{"date":146,"type":31},"2026-02-12",{"date":148,"type":20},"2026-02-26",{"date":150,"type":20},"2027-01-01",{"name":75,"class":38},2]