[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pediatric-cardiac-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pediatric-cardiac-surgery":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,42,75,111,142],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100564196","phase-3-evaluation-of-analgesia-for-cardiac-elective-surgery-in-children-100564196",false,"NCT06626035","Evaluation of Analgesia for Cardiac Elective Surgery in Children","Prospective Randomized Evaluation of Analgesia for Cardiac Elective Surgery in Children (PRECISE Cardiac Trial)","PRECISE","Inclusion Criteria:\n\n* Children aged 3-years - \\\u003C18 years\n* ASA physical status 1, 2, or 3\n* Participant or legal guardian can speak and read English or Spanish\n* Undergoing the following cardiac surgeries (Categories 1 \\& 2) that are associated with significant acute surgical pain\n\nSTS Category 1:\n\n* ASD, PFO closure\n* VSD repairs,\n* Aortic stenosis sub-valvular repair\n* ASD and Partial anomalous venous return repair\n* AV canal transitional\n* Conduit replacement\n* Valve replacement (AVR, PVR)\n* TOF repair without ventriculostomy\n\nSTS Category 2:\n\n* Glenn shunt (on Bypass only)\n* Fontan surgery (on Bypass only)\n* Pulmonary artery plasty (main)\n* Left Atrium (LA) to Pulmonary Artery (PA) conduit replacement.\n\nExclusion Criteria:\n\n* Pregnant patients\n* Methadone allergy\n* Preoperative prolonged QTc more than 460 msec (-30 days to 0 day)\n* Subjects undergoing concomitant treatment with known cytochrome P450 inhibitors included in methadone labeling (i.e. macrolides (e.g. erythromycin), azole-antifungal agents (e.g. ketoconazole, voriconazole), protease inhibitors (e.g. ritonavir), fluconazole, SSRIs (e.g. sertraline, fluvoxamine)\n* Preoperative opioid use within 30 days before surgery\n* History of severe sleep apnea (have a sleep study with an AHI index score more than 10 or clinical signs of sleep disordered breathing - snoring, daytime drowsiness)\n* Significant liver, kidney, neurological disease, developmental delay, or any other co-existing medical condition per discretion of the clinical investigator","ALL","3 Years","18 Years",{"count":21,"type":22},500,"ESTIMATED","INTERVENTIONAL",[25],"PHASE3","The purpose of this study is to look at a standardized methadone-based enhanced recovery after surgery protocol following pediatric cardiac surgery. This study will consist of randomly assigning children to receive the methadone-based recovery procedures or to receive current standard of care recovery procedures. Randomly assigning means that there is a 50\u002F50 chance, like a coin flip, of being assigned to either research group.",[28],"Pediatric Cardiac Surgery","RECRUITING","2026-08-05",{"date":32,"type":33},"2026-08-07","ACTUAL",{"date":35,"type":33},"2025-12-17",{"date":37,"type":22},"2029-08-31",{"name":39,"class":40},"Senthil Sadhasivam","OTHER",3,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100648951","impact-of-preoperative-oral-carbohydrate-loading-on-insulin-resistance-in-pediatric-cardiac-surgery-patients-100648951","NCT07729280","Impact of Preoperative Oral Carbohydrate Loading on Insulin Resistance in Pediatric Cardiac Surgery Patients","The Effect of Preoperative Oral Carbohydrate Loading on Insulin Resistance in Pediatric Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 2-16 years.\n* ASA physical status 2 or 3\n* Good tolerance of enteral feeding\n\nExclusion Criteria:\n\n* History of type 1 diabetes mellitus.\n* History of thyroid insufficiency treated with thyroid medication.\n* History of adrenal insufficiency treated with corticosteroids.\n* History of gastroesophageal reflux disease.\n* Patients receiving preoperative parenteral nutrition.\n* Emergency or urgent cardiac surgery.","2 Years","16 Years",{"count":52,"type":22},44,[54],"NA","Surgical stress and preoperative fasting can induce insulin resistance, characterized by impaired cellular response to insulin and resulting hyperglycemia. In pediatric patients undergoing cardiac surgery, this metabolic stress response may negatively affect postoperative recovery. Although preoperative oral carbohydrate loading, defined as administering a carbohydrate-rich beverage before surgery rather than prolonged fasting, has demonstrated efficacy in reducing postoperative insulin resistance in adults, evidence supporting its use in pediatric cardiac surgery remains limited.\n\nThis randomized controlled trial aims to determine whether preoperative oral carbohydrate loading reduces perioperative insulin resistance, as measured by the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR), in pediatric patients undergoing cardiac surgery. The study will compare outcomes between children who receive an oral carbohydrate beverage prior to surgery and those who follow standard preoperative fasting protocols.",[57,58,28],"Cardiac Surgery","Insulin Resistance",[60,61,62,63],"Cardiac surgery","Carbohydrate loading","Insulin resistance","Glycemic variability","NOT_YET_RECRUITING","2026-07-24",{"date":67,"type":33},"2026-07-27",{"date":69,"type":22},"2026-08-25",{"date":71,"type":22},"2026-11-01",{"name":73,"class":40},"Rifdhani Fakhrudin Nur",1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":19,"enrollmentInfo":82,"targetDuration":4,"studyType":23,"phases":84,"briefSummary":85,"conditions":86,"keywords":92,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":74},"100638712","pulse---patient-understanding-and-learning-through-structured-education---effectiveness-and-implementation-of-patient-education-videos-in-a-new-pediatric-cardiology-clinic-a-stepped-wedge-cluster-randomized-trial-100638712","NCT07594041","PULSE - Patient Understanding and Learning Through Structured Education - Effectiveness and Implementation of Patient Education Videos in a New Pediatric Cardiology Clinic: A Stepped Wedge Cluster Randomized Trial","PULSE","Inclusion Criteria:\n\nPediatric patients (ages 0-18 years) presenting for outpatient pediatric cardiology evaluation Caregiver present and able to complete surveys Referral reason matches available video topic (during intervention periods)\n\nExclusion Criteria:\n\nEmergency or urgent consultations Caregiver unable to read\u002Funderstand English or Spanish Patient\u002Ffamily opts out of study participation",{"count":83,"type":22},300,[54],"This study is looking at whether short educational videos shown during pediatric cardiology visits can help families better understand their child's condition while also making clinic visits run more efficiently. Families coming to a pediatric cardiology clinic may watch short videos related to why they are there (for example: chest pain, heart murmurs, fainting, sports clearance, or Kawasaki disease). The videos are meant to explain common heart-related conditions and answer questions before the doctor comes into the room.\n\nResearchers want to see if this:\n\n* helps parents and patients learn more,\n* improves satisfaction with the visit,\n* helps families feel more involved in decisions,\n* and reduces the amount of time doctors spend repeating the same explanations.\n\nHow the study works:\n\nOne clinic site in San Antonio, TX will start using the videos at different times. Researchers will compare clinic visits before and after the videos are introduced.\n\nWho is included:\n\nChildren being seen in pediatric cardiology clinics and their caregivers. Pregnant women referred for fetal heart evaluations may also be included.\n\nWhat information is collected:\n\nClinic timing information (such as wait times and doctor visit length), Satisfaction surveys, Optional knowledge questionnaires, Basic medical record information needed for the study.\n\nRisk level: The study is considered \"minimal risk.\" Patients are still getting normal medical care. No drugs, devices, or experimental treatments are being tested.\n\nPrivacy protections: Data will be stored on secure hospital systems. Researchers plan to remove identifying information when analyzing results. Medical record numbers are only temporarily used to connect survey data with clinic data.\n\nWhy the study matters:\n\nThe clinic hopes the videos can make visits less stressful, improve understanding for families, and help doctors spend more time on personalized care instead of repeating the same explanations over and over. It may also help clinics work more efficiently and reduce delays.",[87,28,88,89,90,91],"Cardiology","Education","Patient Education","Shared Decision-making","Outpatient Clinics, Hospital",[93,94,95,96,97,98,99,100,101],"patient education","videos","outpatient","pediatric","cardiology","pediatric cardiology","shared decision making","outpatient clinic","implementation science","2026-05-12",{"date":104,"type":33},"2026-05-18",{"date":106,"type":22},"2026-05",{"date":108,"type":22},"2027-12",{"name":110,"class":40},"Driscoll Children's Hospital",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":19,"enrollmentInfo":119,"targetDuration":4,"studyType":121,"phases":4,"briefSummary":122,"conditions":123,"keywords":130,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":4},"100591796","this-is-an-observational-study-that-aims-to-demonstrate-postoperative-risk-factors-in-pediatric-cardiac-surgery-100591796","NCT06985082","This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery","Risk Factors for Postoperative Complications in Pediatric Cardiac Surgery: A Retrospective Observational Study","PEDS-CARE","Inclusion Criteria:\n\n* All patients under 18 years of age who underwent cardiac surgery\n\nExclusion Criteria:\n\n* Patients undergoing non-cardiac thoracic surgeries\n* Patients over 18 years of age\n* Pregnant women will be excluded from the study",{"count":120,"type":22},310,"OBSERVATIONAL","This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil. By analyzing both electronic and physical medical records, researchers will examine demographic, clinical, surgical, and laboratory data, focusing on variables such as cardiopulmonary bypass (CPB) time, use of vasoactive drugs, and the occurrence of complications such as arrhythmias, acute kidney injury, and infections. Statistical analysis will include both descriptive and inferential methods, with multivariate logistic regression used to identify predictors of adverse outcomes. The study will be conducted between 2025 and 2027 with an estimated budget of R$1,000. Its goal is to inform preventive strategies and optimize perioperative care, ultimately improving patient outcomes and reducing hospital costs.",[124,125,126,127,128,129,28],"Arrhythmia","Acute Kidney Injuries","Sepsis","Pneumopathy","Thrombosis","Ventricular Asynchrony in Cardiac Surgery Patients",[28,131,132],"Risk Factors Postoperative","Complications Posoperative","2025-05-14",{"date":135,"type":33},"2025-05-22",{"date":137,"type":22},"2025-05",{"date":139,"type":22},"2025-08",{"name":141,"class":40},"Instituto de Cardiologia do Rio Grande do Sul",{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":147,"acronym":4,"eligibilityCriteria":148,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":23,"phases":152,"briefSummary":153,"conditions":154,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":74},"100570677","the-effect-of-preoperative-albumin-administration-on-postoperative-acute-kidney-injury-in-pediatric-patients-with-hypoalbuminemia-undergoing-cardiac-surgery-100570677","NCT06710353","The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery","The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery: A Prospective Randomized Clinical Trial","Inclusion Criteria:\n\n* Pediatric patients under 7 years of age undergoing cardiac surgery with cardiopulmonary bypass\n* Preoperative serum albumin level of 4.0 g\u002FdL or lower\n\nExclusion Criteria:\n\n* abnormal preoperative creatinine level\n* history of dialysis\n* liver dysfunction\n* diabetes\n* history of hypersensitivity to albumin\n* coagulation disorders","7 Years",{"count":151,"type":22},190,[54],"The study aims to evaluate whether preoperative albumin supplementation in pediatric patients with hypoalbuminemia undergoing cardiac surgery can reduce inflammatory responses and prevent acute kidney injury (AKI) following cardiopulmonary bypass.",[155,28],"Acute Kidney Injury","2025-04-17",{"date":158,"type":33},"2025-04-23",{"date":160,"type":33},"2025-01-09",{"date":162,"type":22},"2027-12-31",{"name":164,"class":40},"Seoul National University Hospital"]