[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"penetration-of-irrigant-in-the-root-canal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:penetration-of-irrigant-in-the-root-canal":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100649086","effectiveness-of-three-different-irrigation-methods-during-a-root-canal-treatment-100649086",false,"NCT07731594","Effectiveness of Three Different Irrigation Methods During a Root Canal Treatment","Effect of Various Irrigant Activation Methods and Its Penetration in the Apical Third of Root Canal","Inclusion Criteria:\n\n* Straight Canals\n* Single Rooted 1st and 2nd mandibular premolars with closed apices\n\nExclusion Criteria:\n\n* Mandibular premolars with open apices\n* Mandibular premolars with curved or calcified canals",true,"ALL","20 Years","50 Years",{"count":21,"type":22},105,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to compare the effectiveness of three root canal irrigation techniques-Conventional Needle Irrigation (CNI), Side-Vented Needle (SVN), and Ultrasonic Irrigation (UI)-in achieving irrigant penetration into the apical third of the root canal. Since conventional irrigation often fails to adequately clean complex root canal anatomy, the study evaluates whether activation methods improve irrigant penetration. A randomized controlled trial will compare these three techniques using extracted single-rooted mandibular premolars. A radiopaque dye mixed with sodium hypochlorite will be used to measure irrigant penetration on digital radiographs, and the results will be statistically analyzed to determine the most effective irrigation method.",[28,29],"Three Canal Irrigation Methods and Their Comparison","Penetration of Irrigant in the Root Canal","NOT_YET_RECRUITING","2026-07-25",{"date":33,"type":34},"2026-07-28","ACTUAL",{"date":36,"type":22},"2026-07-12",{"date":38,"type":22},"2026-12-26",{"name":40,"class":41},"Pakistan Institute of Medical Sciences","OTHER_GOV"]