[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"peri-implant-mucosa-thickness\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:peri-implant-mucosa-thickness":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100650512","phase-2-hyaluronic-acid-vs-i-prf-with-microneedling-in-enhancing-peri-implant-soft-tissue-100650512",false,"NCT07750756","Hyaluronic Acid vs I-PRF With Microneedling in Enhancing Peri-implant Soft Tissue","Hyaluronic Acid Versus I-PRF Combined With Microneedling for Peri Implant Soft Tissue Enhancement: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients with delayed implants placed in the maxillary esthetic region in correct positioning and angulation\n* Patients with peri-implant gingival thickness ≤ 1 mm\n* Patients with healthy gingiva and who can maintain good oral hygiene around implants\n\nExclusion Criteria:\n\n* Marginal bone loss ≤ 2 mm\n* Patients with peri-implantitis or periodontitis\n* Patients with systemic conditions or diseases impairing healing or soft tissue metabolism\n* Pregnant or lactating females\n* Patients taking medications affecting the gingiva","ALL","21 Years","50 Years",{"count":20,"type":21},42,"ESTIMATED","INTERVENTIONAL",[24,25],"PHASE2","PHASE3","This study aims to compare the use of microneedling alone versus with hyaluronic acid or i-PRF in conjunction with microneedling in peri-implant mucosa in the esthetic zone to test the superior increase in gingival thickness.",[28],"Peri-implant Mucosa Thickness",[30,31,32,33,34],"microneedling","hyaluronic acid","I-PRF","gingival thickness","peri-implant","NOT_YET_RECRUITING","2026-08-14",{"date":38,"type":39},"2026-08-17","ACTUAL",{"date":41,"type":21},"2026-10-30",{"date":43,"type":21},"2028-05-30",{"name":45,"class":46},"Ain Shams University","OTHER"]