[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"peri-implant-soft-tissue-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:peri-implant-soft-tissue-deficiency":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,56],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100647973","soft-tissue-augmentation-around-dental-implants-using-connective-tissue-graft-submerged-tenting-abutment-or-sub-crestal-implant-placement-100647973",false,"NCT07714265","Soft Tissue Augmentation Around Dental Implants Using Connective Tissue Graft, Submerged Tenting Abutment, or Sub-crestal Implant Placement","Evaluation of Peri-implant Soft Tissue Thickness Following Augmentation Using Subepithelial Connective Tissue Graft Versus Submerged Tenting Abutment Versus Sub-crestal Implant Placement: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Adults aged 20 years or older.\n* Partially edentulous patients requiring a single dental implant in the posterior mandible.\n* Thin peri-implant soft tissue phenotype (\\\u003C2 mm).\n* Horizontal alveolar ridge width of at least 6 mm.\n* Vertical bone height of at least 10-12 mm, confirmed radiographically.\n* Adequate interarch restorative space for implant-supported restoration.\n* Medically healthy (American Society of Anesthesiologists \\[ASA\\] Physical Status I or II).\n* Good oral hygiene.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Local pathological lesions affecting the surgical site.\n* Smoking.\n* Pregnancy or breastfeeding.\n* Alcohol abuse or parafunctional habits that may compromise implant survival or wound healing.\n* Medical or local conditions that could interfere with osseointegration, soft tissue healing, or study participation","ALL","20 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","Peri-implant soft tissue thickness is an important determinant of the long-term stability and success of dental implants. Patients with a thin peri-implant soft tissue phenotype are at increased risk of soft tissue recession, marginal bone loss, and compromised esthetic and functional outcomes. Subepithelial connective tissue graft (SCTG) is considered the gold standard for soft tissue augmentation; however, it requires harvesting tissue from the palate, increasing surgical complexity, operative time, and postoperative morbidity. Less invasive approaches, including submerged tenting abutments and subcrestal implant placement, have been proposed as alternatives to improve peri-implant soft tissue dimensions while reducing patient morbidity, but direct comparative clinical evidence remains limited.\n\nThis investigator-initiated, single-center, randomized, parallel-group clinical trial will compare three approaches for peri-implant soft tissue augmentation in patients with a thin peri-implant soft tissue phenotype requiring a single dental implant in the posterior mandible. Eligible implant sites will be randomly assigned in a 1:1:1 allocation ratio to receive either subepithelial connective tissue grafting, submerged tenting abutment placement, or subcrestal implant placement during implant surgery.\n\nThe primary objective is to compare changes in peri-implant soft tissue thickness using three-dimensional digital intraoral scanning over a 12-month follow-up period. Secondary objectives include evaluation of keratinized tissue width, clinical soft tissue thickness, histological characteristics of peri-implant soft tissue, peri-implant crestal bone level changes, postoperative pain, operative time, patient-reported satisfaction, and postoperative complications. The results of this study are expected to provide evidence regarding whether minimally invasive treatment approaches can achieve clinical outcomes comparable to connective tissue grafting while reducing surgical morbidity and improving patient-centered outcomes.",[26,27,28],"Peri-implant Soft Tissue Deficiency","Partial Edentulism","Tooth Loss",[30,31,32,33,34,35,36,37,38,39,40,41,42],"Dental Implant","Peri-implant Soft Tissue","Soft Tissue Augmentation","Tenting Healing Abutment","Subepithelial Connective Tissue Graft","Digital Volumetric Analysis","Randomized Controlled Trial","Posterior Mandible","Submerged Tenting Abutment","Thin Peri-implant Phenotype","Subcrestal Implant Placement","SCTG","Digital Intraoral Scanner","RECRUITING","2026-07-18",{"date":46,"type":47},"2026-07-21","ACTUAL",{"date":49,"type":20},"2026-07-17",{"date":51,"type":20},"2027-12-15",{"name":53,"class":54},"Misr International University","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":16,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":21,"phases":67,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":55},"100621504","ctg-versus-collagen-matrix-for-peri-implant-soft-tissue-augmentation-100621504","NCT07371481","CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation","Results of Soft Tissue Grafting Around Implant in the Mandible Molar Area","Inclusion Criteria:\n\nAdults aged 18 to 65 years.\n\nPatients requiring dental implant treatment in the mandibular molar region.\n\nPresence of insufficient peri-implant soft tissue thickness (\\\u003C 2 mm).\n\nAdequate general health to undergo minor oral surgery.\n\nAbility and willingness to provide written informed consent and comply with study procedures.\n\nExclusion Criteria:\n\nSystemic conditions or medications that may impair wound healing.\n\nHeavy smoking (more than 10 cigarettes per day).\n\nHistory of allergy or hypersensitivity to collagen-based materials.\n\nPrevious graft failure or complications at the intended implant site.\n\nLoss of three or more adjacent teeth in the study area (excluding third molars).","18 Years","65 Years",{"count":66,"type":20},46,[23],"This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix. Adult patients requiring implant treatment with insufficient peri-implant soft tissue thickness will be randomly assigned to receive either CTG or a collagen matrix at the time of implant surgery.\n\nThe study aims to evaluate and compare changes in peri-implant soft tissue thickness, width of keratinized tissue, and soft tissue contour over a 9-month follow-up period, as well as the occurrence of postoperative complications. The results of this study will help determine whether a collagen matrix can provide clinical outcomes comparable to those of connective tissue grafting for peri-implant soft tissue augmentation.",[26,70],"Insufficient Peri-implant Keratinized Tissue",[72,73,74,75],"Peri-implant soft tissue augmentation","Connective tissue graft","Collagen matrix","Dental implant","NOT_YET_RECRUITING","2026-01-27",{"date":79,"type":47},"2026-01-29",{"date":81,"type":20},"2026-02",{"date":83,"type":20},"2028-12",{"name":85,"class":54},"Hanoi Medical University"]