[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perianal-abscess\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perianal-abscess":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,40,73,111,135,159,189],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":36,"locationsCount":39},"100650158","study-on-dynamic-multimodal-analgesia-regimen-integrated-with-traditional-chinese-and-western-medicine-after-perianal-abscess-surgery-100650158",false,"NCT07744594","Study on Dynamic Multimodal Analgesia Regimen Integrated With Traditional Chinese and Western Medicine After Perianal Abscess Surgery","Study on Dynamic Multimodal Analgesia Regimen Integrated With Traditional Chinese and Western Medicine After Perianal Abscess Surgery: A Single-Center, Prospective, Open-Label Randomized Clinical Trial","Inclusion Criteria:\n\n1. Aged between 18 and 75 years old (18 ≤ age ≤ 75);\n2. Diagnosed with primary perianal abscess via digital rectal examination, anorectal ultrasound or MRI, and scheduled for incision and drainage or radical surgery;\n3. The maximum diameter of the abscess cavity ≥ 2 cm, or with obvious abscess cavity formation;\n4. Patients are willing and capable of participating in the pain management protocol, fully understand the significance of pain management, and can actively cooperate with study procedures;\n5. No severe coagulation disorders.\n\nExclusion Criteria:\n\n1. Complicated with specific infectious diseases such as Crohn's disease and tuberculosis;\n2. Unclear source of postoperative pain, i.e., the origin of pain cannot be confirmed or the pain is unrelated to surgery;\n3. Presence of definite contraindications, including drug allergy or inability to tolerate any pain management measures adopted in this trial;\n4. Pregnant or lactating women;\n5. Patients unable to cooperate with the study, such as those with cognitive impairment, history of mental illness, communication barriers and other conditions;\n6. Patients with long-term analgesic medication use and established drug tolerance;\n7. Complicated with uncontrolled cardiovascular and cerebrovascular diseases (NYHA cardiac function class Ⅲ-Ⅳ), hepatic and renal insufficiency (Child-Pugh class C or eGFR \\\u003C 30 mL\u002Fmin\u002F1.73 m²), etc.;\n8. Abscess secondary to rectal neoplasms, trauma or iatrogenic injury;\n9. Severe postoperative complications (such as massive hemorrhage, sepsis) or concurrent infections at other sites;\n10. Patients receiving only non-surgical treatments such as simple needle aspiration of pus.","ALL","18 Years","75 Years",{"count":20,"type":21},147,"ESTIMATED","INTERVENTIONAL",[24],"NA","Background:Perianal abscess is a common acute anorectal pyogenic disease (8%-25% of anorectal illnesses), mainly seen in men aged 20-40. Over 90% suffer severe postoperative pain, impairing healing, triggering anxiety or sepsis and raising medical loads. Western multimodal analgesia eases pain yet causes dependence and side effects. TCM sitz baths clear heat, reduce swelling and promote recovery. Few personalized combined protocols are available, and integrated Chinese-Western synergies are insufficiently exploited. This optimized integrated intervention guides postoperative pain nursing.",[27],"Perianal Abscess","NOT_YET_RECRUITING","2026-08-02",{"date":31,"type":32},"2026-08-04","ACTUAL",{"date":34,"type":21},"2026-07-30",{"date":34,"type":21},{"name":37,"class":38},"The Affiliated Hospital of Putian University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":22,"phases":50,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":39},"100647131","phase-4-antibiotics-after-incision-and-drainage-to-prevent-fistula-formation-after-first-episode-of-perianal-abscess-100647131","NCT07704359","Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal Abscess","Randomized Antibiotics for Prevention of Fistula After Incision and Drainage of First-Episode Perianal Abscess (RAPID): A Randomized Controlled Trial","RAPID","Inclusion Criteria:\n\n* Age 18 years or older\n* First episode of perianal abscess requiring incision and drainage\n* Able to provide informed consent\n* English or Spanish speaking patient\n* Treating surgical team has determined that incision and drainage is clinically indicated as part of standard care\n\nExclusion Criteria:\n\n* Known fistula-in-ano at presentation\n* Prior perianal abscess within 12 months\n* History of inflammatory bowel disease, including Crohn's disease or ulcerative colitis\n* Known or suspected anorectal malignancy\n* Necrotizing soft tissue infection or Fournier's gangrene\n* Systemic infection or sepsis\n* Significant surrounding cellulitis or extensive soft-tissue infection for which antibiotics are clinically indicated\n* Immunocompromised or immunosuppressed status, including active chemotherapy or radiation therapy, history of transplant, chronic systemic steroids, biologic immunosuppressive therapy, advanced or uncontrolled HIV\u002FAIDS, or other clinically significant immunosuppression\n* Cardiac condition requiring antibiotic prophylaxis or antibiotic therapy for procedures involving infected tissue\n* Need for non-study antibiotics at the time of enrollment for another infection or medical indication\n* Contraindication, allergy, or intolerance to all study antibiotic regimens\n* Pregnant\n* Prisoner\n* Minor\n* Adult unable to provide informed consent",{"count":49,"type":21},236,[51],"PHASE4","The goal of this clinical trial is to learn if antibiotics can prevent the formation of fistula-in-ano after incision and drainage of a first time of perianal abscess in adults. A perianal abscess is a collection of infected fluid near the anus. A Fistula-in-ano is an abnormal tunnel that can form between the anal canal and the skin after an abscess.\n\nThe main questions it aims to answer are:\n\nDoes taking antibiotics after incision and drainage of a perianal abscess lower the chance of developing a Fistula-in-ano? What medical problems or side effects do participants have after taking antibiotics or not taking antibiotics?\n\nResearchers will compare participants who recieve antibiotics after abscess drainage with paticipants who do not recieve antibiotics after abscess drainage, to see if antibiotics lower the chance of developing a Fistula-in-ano.\n\nParticipants will:\n\nBe randomly assigned to recieve antibiotics for 7 days after abscess incision and drainage or to not recieve antibiotics after abscess incision and drainage.\n\nAttend follow-up clinic visits after incision and drainage as part of their standard of care.\n\nComplete follow-up phone call about 12 months after incision and drainage. Allow the study team to review their medical record for abscess treatment, symptoms, recurrence, fistula-in-ano formation, additional procedures, and antibiotics side effects.",[27,54],"Anal Fistula",[56,57,58,59,60,61,62,63],"Perianal abscess","Anal fistula","Fistula-in-ano","Incision and Drainage","Antibiotics","Amixicillin clavulanate","Metronidazole","Ciprofloxacin","2026-07-09",{"date":66,"type":32},"2026-07-15",{"date":68,"type":21},"2026-08-03",{"date":70,"type":21},"2029-08-03",{"name":72,"class":38},"University of Illinois at Chicago",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":81,"targetDuration":83,"studyType":84,"phases":4,"briefSummary":85,"conditions":86,"keywords":92,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":39},"100632912","the-impact-of-perianal-disease-on-patients-sex-life-100632912","NCT07519850","The Impact of Perianal Disease on Patient's Sex Life","The \"Hidden Morbidity\" of Perianal Disease: A Prospective Evaluation of Psychosexual Health and Body Image.","SEXTON","Inclusion Criteria:\n\n* Diagnosis of chronic perianal disease (fistula-in-ano, pCD, pilonidal).\n* Age \\>18 years.\n* Ability to understand and complete the Greek versions of the IIEF-5\u002FFSFI-6 and the study PROM.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Active malignancy (colorectal or anal cancer).\n* Major pelvic surgery in the last 3 months (unrelated to perianal disease).\n* Cognitive impairment preventing survey completion.",{"count":82,"type":21},60,"3 Months","OBSERVATIONAL","Perianal diseases, such as perianal abcesses, anal fistulae and perianal Crohn's disease, are often associated with significant physical symptoms, including pain and chronic drainage. However, the impact of these conditions on a patient's personal life, intimacy, and body image-often referred to as \"hidden morbidity\"-is frequently overlooked in clinical practice.\n\nThe purpose of this prospective observational study is to evaluate the psychosexual burden in patients suffering from chronic perianal disease. Using validated tools (IIEF-5 for men, FSFI-6 for women) and a specialized Supplemental Patient-Reported Outcome Measure (PROM), researchers will investigate how the presence of surgical devices (such as setons), disease etiology, and clinical symptoms affect sexual function and self-esteem.\n\nThe study also aims to identify gaps in physician-patient communication regarding sexual health. By quantifying these impacts, the study seeks to promote a more holistic, patient-centered approach to the surgical management of perianal conditions.",[87,88,89,27,90,91],"Perianal Crohn Disease","Perianal Fistula","Fistula in Ano","Pilonidal Cyst\u002FFistula","Anal Fissure and Fistula",[93,94,95,96,97,98,99,100],"fistula in ano","perianal fistula","perianal Crohn's disease","anal fissure","psychosexual life","sex life","intimacy","fistula","RECRUITING","2026-04-02",{"date":104,"type":32},"2026-04-09",{"date":106,"type":21},"2026-03-31",{"date":108,"type":21},"2026-06-20",{"name":110,"class":38},"AHEPA University Hospital",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":118,"targetDuration":4,"studyType":22,"phases":120,"briefSummary":121,"conditions":122,"keywords":123,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":39},"100603889","effect-of-different-sitz-bath-methods-on-perianal-abscess-after-surgery-100603889","NCT07142382","Effect of Different Sitz Bath Methods on Perianal Abscess After Surgery","Effect of Different Hip Bathing Methods on Perianal Abscess After Surgery: a Single-center, Prospective, Open-label Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged between 18 and 75 years\n* Patients were diagnosed with perianal abscess\n* Underwent perianal abscess treatment\n* Underwent sitz bath after surgery\n\nExclusion Criteria:\n\n* Patients with recurrent perianal abscesses or those with concurrent formation of anal fistulas;\n* Patients with Crohn's disease;\n* Patients with mental disorders;\n* Pregnant or lactating women;\n* Patients with diabetes;\n* Patients with a history of malignant tumor treatment within the past 5 years. ； -Patients who are using immunosuppressants or steroids",{"count":119,"type":21},102,[24],"Perianal abscess is a purulent infection of the tissues surrounding the anal canal and rectum. The postoperative wound is prone to infection, and the literature indicates that hip bathing is helpful to prevent infection, reduce edema, and promote healing. Therefore, patients need to use a bidet for medical sitz bath to avoid infection and contamination. The bidet on the market is divided into ordinary type and rinse type (manual or electric). There are no high-quality studies comparing the effects of these sitz baths.\n\nA prospective randomized controlled trial was designed to investigate the effects of regular sitz bath, manual irrigation, and electric irrigation. A total of 102 patients with perianal abscess in the Affiliated Hospital of Putian University were included in the study. The patients were 18-75 years old and underwent surgical treatment. Patients with recurrent abscess, anal fistula, mental disease, pregnant or lactating women, and diabetes were excluded. The patients were divided into general group, manual group and electric group by random number table method, with 34 cases in each group. All patients received hip bathing with 0.02% potassium permanganate solution at 41-43 ° C three times a day for 10-15 minutes each time after surgery.",[27],[124,125,126],"sitz bath","perianal absecess","Wound healing","2025-09-13",{"date":129,"type":32},"2025-09-18",{"date":131,"type":21},"2025-09-15",{"date":133,"type":21},"2026-12-30",{"name":37,"class":38},{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":4,"eligibilityCriteria":141,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":142,"targetDuration":4,"studyType":22,"phases":144,"briefSummary":145,"conditions":146,"keywords":147,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":156,"leadSponsor":158,"locationsCount":39},"100604887","effect-of-red-and-blue-light-irradiation-on-postoperative-wound-healing-in-perianal-absces-100604887","NCT07155356","Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces","Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Abscess: a Single-center Prospective Open-label Randomized Clinical Trial","Inclusion Criteria:\n\n* Aged between 18 and 75 years;\n* Clinical diagnosis of perianal abscess；\n* Procedure: Radical resection with incision and drainage.\n\nExclusion Criteria:\n\n* Concurrent anorectal disorders (hemorrhoids, anal fissure) or malignancies\u002Finfectious diseases；\n* History of psychiatric disorders；\n* Analgesic use within 7 days preoperatively；\n* Coagulopathy or cardiac\u002Fhepatic dysfunction；\n* Pregnancy or lactation；\n* Contraindications to phototherapy；\n* IBD-related perianal abscess.",{"count":143,"type":21},222,[24],"This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery. A total of 222 eligible patients were randomly allocated equally into three groups (74 per group):①Routine Care Group: Standard wound care including cleansing and dressing changes；②Red Light Therapy Group: Routine care plus red light phototherapy；③Combined Red-Blue Light Therapy Group: Routine care plus concurrent red and blue light phototherapy.Wound healing time and incidence of complications were compared to assess postoperative recovery across interventions. The primary hypothesis posits that adjunctive phototherapy-particularly combined red-blue light irradiation-will significantly enhance wound healing, reduce edema and pain, and decrease complication rates (e.g.bleeding, urinary retention) compared to routine care alone.",[27],[148,149,150,151],"perianal abscess","red light phototherapy","red and blue light phototherapy","wound healing","2025-09-01",{"date":154,"type":32},"2025-09-04",{"date":131,"type":21},{"date":157,"type":21},"2026-09-30",{"name":37,"class":38},{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":164,"acronym":165,"eligibilityCriteria":166,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":167,"targetDuration":169,"studyType":84,"phases":4,"briefSummary":170,"conditions":171,"keywords":172,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":4},"100594445","machine-learning-based-risk-stratification-for-fistula-formation-after-perianal-abscess-drainage-100594445","NCT07019532","Machine Learning-Based Risk Stratification for Fistula Formation After Perianal Abscess Drainage","A Prospective Cohort Study for Machine Learning-Based Prediction of Anal Fistula Formation After Perianal Abscess Drainage Based on Drainage Setting, Provider Experience, and MRI Interpretation (PRISM)","PRISM","Inclusion Criteria:\n\n* Age ≥ 18\n* First-time perianal abscess\n* Surgical drainage performed\n\nExclusion Criteria:\n\n* Existing anal fistula history\n* Crohn's disease\n* Immunosuppressive treatment\n* Incomplete 6-month follow-up",{"count":168,"type":21},450,"6 Months","This prospective cohort study investigates the influence of provider experience and drainage location on fistula formation within 6 months following perianal abscess drainage. Additionally, the study explores the role of artificial intelligence (AI)-based interpretation of magnetic resonance (MR) images in early identification of fistula development.",[27,54],[173,174,175,176,177,178],"Artificial Intelligence","MR Imaging","Colorectal Surgery","Surgical Outcomes","Drainage","Fistula Prediction","2025-06-05",{"date":181,"type":32},"2025-06-13",{"date":183,"type":21},"2025-07-01",{"date":185,"type":21},"2026-06-01",{"name":187,"class":188},"Gumushane State Hospital","OTHER_GOV",{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":196,"targetDuration":4,"studyType":22,"phases":198,"briefSummary":199,"conditions":200,"keywords":203,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":39},"100232647","multicenter-study-for-diagnosis-and-treatment-of-perianal-abscesses-100232647","NCT02306382","Multicenter Study for Diagnosis and Treatment of Perianal Abscesses","Randomized Controlled Multicenter Study for Diagnosis and Treatment of Perianal Abscesses.","Inclusion Criteria:\n\n* perianal abscess that needs surgical treatment, over the age of 18\n\nExclusion Criteria:\n\n* Under the age of 18 or unable to understand study information because of language difficulties or dementia.",{"count":197,"type":21},200,[24],"Drainage of perianal abscesses is a well established treatment. Traditionally its been done in general anesthesia after the swelling has been localised its been drained with a knife. After surgical intervention complications can occur with recidivism, chronic fistulas that go from the anal to the skin and sometimes the anal sphincter is damaged which can cause problems with incontinence.\n\nThrough ultrasound the abscess is opened under more controlled forms with a better visual overview. This is a new technique that has not been tested in larger studies. The aim with ultrasound-drainage as with traditional incision to drain the abscess so that the infected area can heal.\n\nThe hypothesis is a reduction of recurrences and formation of fistulas with the use of 3D ultrasonography.",[27,201,202],"Anal Fistulas","Incontinence",[204,205,148,206,207],"endoanal ultrasonography","drainage","fistulas","incontience","2023-11-28",{"date":210,"type":32},"2023-11-29",{"date":212,"type":4},"2012-12",{"date":214,"type":21},"2028-12",{"name":216,"class":38},"University Hospital, Umeå"]