[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"persistent-symptomatic-apical-periodontitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:persistent-symptomatic-apical-periodontitis":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100655070","to-evaluate-and-compare-the-effect-of-orthograde-and-retrograde-mta-root-end-filling-after-periapical-surgery-in-posteriors-100655070",false,"NCT07808424","To Evaluate and Compare the Effect of Orthograde and Retrograde MTA Root End Filling After Periapical Surgery in Posteriors","To Evaluate and Compare the Effect of Orthograde and Retrograde MTA Root End Filling on Clinical, 2D and 3D Radiographic Success and Quality of Life After Periapical Surgery in Posteriors- A Randomised Control Trial","Inclusion Criteria:\n\n* Patients in which non-surgical retreatment is unfeasible (anatomical complexity, iatrogenic errors) or previously failed treatment in cases of persistent symptomatic apical periodontitis involving posteriors.\n* Tooth with a peri-radicular lesion of endodontic origin (chronic apical periodontitis) or endo-perio origin with the size of lesion ≥5mm.\n* Teeth with less than 10 degree root curvature.\n* Patients between 18-55 years of age.\n* No general medical contraindications for oral surgical procedures (ASA-1 according to the classification of the American Society of Anesthesiologists)\n* Tooth with adequate final restoration without clinical evidence of coronal leakage.\n* Good periodontal health condition at tooth level.\n* Able to completely understand and sign an informed consent form.\n\nExclusion Criteria:\n\n* • Patients with systemic diseases (diabetes mellitus, uncontrolled hypertension grade III, hepatic\u002Frenal disease, or systemic bleeding disorders) (Bharathi et al 2021).\n\n  * Patients on anticoagulant\u002F antiplatelet drugs.\n  * Fractured\u002Fperforated teeth.\n  * Presence of vertical root fracture.\n  * Pregnancy.",true,"ALL","18 Years","55 Years",{"count":21,"type":22},54,"ESTIMATED","INTERVENTIONAL",[25],"NA","To evaluate and compare the effect of orthograde and retrograde MTA root end filling on clinical, 2D and 3D radiographic success and quality of life after periapical surgery in posteriors- A Randomised Control Trial",[28,29],"Non Vital Teeth","Persistent Symptomatic Apical Periodontitis",[31],"persistant symptomatic apical periodontitis","RECRUITING","2026-09-07",{"date":35,"type":36},"2026-09-08","ACTUAL",{"date":38,"type":36},"2026-04-29",{"date":40,"type":22},"2027-10-28",{"name":42,"class":43},"Postgraduate Institute of Dental Sciences Rohtak","OTHER"]