[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"photorefractive-keratectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:photorefractive-keratectomy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100647144","comparison-of-ketorolac-tromethamine-05-soaked-bandage-contact-lenses-versus-non-medicated-bandage-contact-lenses-on-postoperative-pain-control-after-photorefractive-keratectomy-100647144",false,"NCT07705763","Comparison of Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses Versus Non-Medicated Bandage Contact Lenses on Postoperative Pain Control After Photorefractive Keratectomy","Inclusion Criteria:\n\n* Participants selected to undergo photorefractive keratectomy for correction of refractive error after complete workup.\n* Participants willing to participate in the study after detailed explanation of the research purpose.\n\nExclusion Criteria:\n\n* Known hypersensitivity to NSAIDs or ketorolac.\n* Presence of any systemic diseases affecting wound healing.","ALL","21 Years","40 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","Photorefractive keratectomy (PRK) is a well-established surface ablation procedure for the correction of refractive errors. Despite excellent visual and refractive outcomes, postoperative pain remains a significant concern, particularly during the first few days following surgery. This pain is primarily related to corneal epithelial removal, exposure of subepithelial nerve endings, and the subsequent inflammatory response. Effective pain management is therefore essential to enhance patient comfort, improve compliance with postoperative care, and increase overall surgical satisfaction. Therefore we will compare postoperative pain levels in patients undergoing PRK using ketorolac tromethamine 0.5%-soaked bandage contact lenses versus non-medicated bandage contact lenses.",[26,27],"Refraction Error","Photorefractive Keratectomy",[29,30,31],"Ketorolac tromethamine","Non-Medicated Bandage Contact Lenses","Postoperative Pain Control","NOT_YET_RECRUITING","2026-07-10",{"date":35,"type":36},"2026-07-15","ACTUAL",{"date":38,"type":20},"2026-08-01",{"date":40,"type":20},"2026-10-31",{"name":42,"class":43},"Madina Teaching Hospital Faisalabad","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":15,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":4},"100573616","a-comparative-study-between-laser-and-manual-removal-of-corneal-epithelium-for-photorefractive-keratectomy-100573616","NCT06748599","A Comparative Study Between Laser and Manual Removal of Corneal Epithelium for Photorefractive Keratectomy","Inclusion Criteria:\n\n* • Age : older than 18 years old .\n\n  * Gender: Include both males and females.\n  * Stable refraction for at least 12 months .\n  * Intraocular pressure less than 21mmHg.\n  * A period without wearing contact lenses (more than 4 days for soft , more than 2 weeks for rigid contact lenses )\n  * No history of any Autoimmune disease .\n  * The refractive error must be one that can be treated by PRK\n\nExclusion Criteria:\n\n* \\_ patients with any eye disease (significant cataract or unstable glaucoma )\n\n  * uncontrolled external disease such as blepharitis, dry eye syndrome, and atopy\u002Fallergy.\n  * patients with Keratoconus and other abnormalities of the cornea such as corneal ectasias , thinning , edema , interstitial or neurotrophic keratitis and extensive vascularisation .\n  * Patients with active systemic connective tissue disease such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)\n  * Ineligibility for Surgery: Exclude patients who are not suitable candidates for surgery .\n  * Consider excluding pregnant or lactating women .\n  * Patients unwilling to participate in the study .","18 Years",{"count":53,"type":20},64,"OBSERVATIONAL","Photorefractive keratectomy (PRK) is a laser eye surgery used to ablate the corneal stroma to correct visual refractive errors . PRK was developed in 1983 by Dr. Steven Trokel and colleagues and first performed in 1987 by Dr. Theo Seiler in Berlin. After receiving approval by the US Food and Drug Administration (FDA) in 1996, PRK was briefly the preferred surgical treatment of ametropia as it provided more predictable and stable results than incisional keratotomy. However, the number of PRK procedures fell in the late 1990s with the growing popularity of laser in situ keratomileusis (LASIK).\n\nThe study aims to compare the visual and refractive outcomes along with the pain score and patient satisfaction after photorefractive keratectomy in patients who underwent transepithelial or mechanical removal technique",[27],[58],"removal of corneal epithelium","2024-12-19",{"date":61,"type":36},"2024-12-27",{"date":63,"type":20},"2025-01-01",{"date":65,"type":20},"2026-03-01",{"name":67,"class":43},"Assiut University"]