[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"polygraphy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:polygraphy":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100654616","sleep-assessment-in-patients-between-high-altitude-ha-vs-sea-level-la-in-patients-with-pulmonary-arterial-hypertension-pah-100654616",false,"NCT07801963","Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH","Effect of a One-week Descent From 2850m to Sea Level and Re-ascent in Patients With Pulmonary Arterial Hypertension and Healthy Controls Permanently Living > 2600m on Pulmonary Hemodynamics, Exercise Capacity, Blood Oxygenation, Sleep Disordered Breathing and Further Outcomes","Inclusion Criteria:\n\n* Adult patients aged 18-80 years and of all genders\n* Permanent residence \\> 2600 m\n* Diagnosis of pulmonary arterial hypertension PAH (PAHHA-Group) according to guidelines\n* Patients are stable on therapy\n* NYHA (new york heart association) functional class I-III.\n* written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>80 years\n* unstable condition\n* Patients who cannot follow the study investigations\n* Patient permanently living \\\u003C 2600m.\n* Patients who traveled and stayed overnight at altitudes \\\u003C2000 m in the past 4 weeks.\n* Patients with moderate to severe concomitant lung disease (FEV1\\\u003C70% or forced vital capacity \\\u003C70%), severe parenchymal lung disease, severe smokers (\\>20 cigarettes\u002Fday)\n* Severely hypoxemic patients at Quito permanently having persistent SpO2 (oxygen saturation by pulseoximetry) \\\u003C80% on ambient air.\n* Patient with a non-corrected ventricular septum defect\n* Relevant concomitant other disease of the heart, kidney, liver, blood (anemia hemoglobin\\\u003C11 g\u002Fdl)","ALL","18 Years","80 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in patients with pulmonary arterial hypertension PAH, who live permanently \\>2600m.",[27,28,29,30,31,32,33],"Pulmonary Arterial Hypertension (PAH)","Pulmonary Vascular Disease","Polygraphy","Sleep","Sleep Disordered Breathing (SDB)","High Altitude Effects","High Altitude",[27,35,33,36,29,30,37,38],"Hypoxia","Pulmonary Hypertension","Sleep disordered breathing SDB","Pulmonary vascular disease","NOT_YET_RECRUITING","2026-08-31",{"date":42,"type":43},"2026-09-03","ACTUAL",{"date":45,"type":21},"2026-09-25",{"date":47,"type":21},"2026-12-31",{"name":49,"class":50},"Silvia Ulrich Somaini","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":14,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":69,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":72,"locationsCount":51},"100654598","sleep-assessment-in-patients-between-high-altitude-ha-vs-sea-level-la-in-healthy-individuals-h-100654598","NCT07801950","Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Healthy Individuals H","Inclusion Criteria:\n\n* Adults aged 18-80 years and of all genders\n* Permanent residence \\> 2600 m\n* healthy: no self-perceived cardiopulmonary disease limiting daily activities\n* written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>80 years\n* Participants who cannot follow the study investigations\n* Participants permanently living \\\u003C 2600m.\n* Participants who traveled and stayed overnight at altitudes \\\u003C2000 m in the past 4 weeks.\n* any self-perceived cardiopulmonary disease limiting daily activities",true,{"count":60,"type":21},14,[24],"To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in healthy individuals, who live permanently \\>2600m.",[64,65,32,33,29,30,31],"Healthy","Healthy Adult",[67,33,29,30,68],"Health","Sleep disordered breathing",{"date":42,"type":43},{"date":45,"type":21},{"date":47,"type":21},{"name":49,"class":50}]