[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"polyhandicap\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:polyhandicap":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,39],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100578449","third-wave-of-the-eval-plh-polyhandicap-cohort-new-eyes-100578449",false,"NCT06811441","Third Wave of the EVAL-PLH (POLYhandicap) Cohort: New Eyes","EVAL-POLYNE","Inclusion Criteria:\n\n* Patient with PIMD\u002FPolyhandicap\n* Patient for whom the legal representative has received the information note of the EVAL-PLH cohort and has not expressed opposition to the collection of patient data;\n* Patient aged at least 3 years;\n* Patient affiliated to a health insurance scheme;\n* Patient treated within the department of the participating center;\n* Patient for whom the legal representative understands the French language;\n* Patient with a PIMD\u002FPolyhandicap\n\nFamily caregivers of patient\n\n* Subject identified by the care structure as the reference family caregiver;\n* Subject aged at least 18 years;\n* Subject who understands the French language and is able to complete self-questionnaires;\n* Subject who has received the information notice and has not expressed opposition to participating in this project\n\nInstitutinal caregivers of patient\n\n* Subject identified by the care structure as the reference institutional caregiver of at least one patient included in this project;\n* Subject aged at least 18 years;\n* Subject who understands the French language and is able to complete self-questionnaires;\n* Subject who has received the information notice and has not expressed opposition to participating in this project.\n\nExclusion Criteria:\n\n* Patient with PIMD\u002FPolyhandicap\n* Patient not meeting all inclusion criteria;\n* Patient in exclusion period of another research protocol at the time of inclusion.\n\nFamily and Institutional caregivers of patient\n\n• Subject not meeting all inclusion criteria",true,"ALL","3 Years",{"count":20,"type":21},1102,"ESTIMATED","OBSERVATIONAL","The general objective of the EVAL-PolyNE project is to improve the representativeness of the EVAL-PLH cohort by broadening participation in the John Bost Foundation, due to its geographical particularity and its private valence.",[25],"Polyhandicap","RECRUITING","2026-10-07",{"date":29,"type":30},"2026-10-13","ACTUAL",{"date":32,"type":30},"2025-10-13",{"date":34,"type":21},"2028-09-01",{"name":36,"class":37},"Assistance Publique Hopitaux De Marseille","OTHER",6,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100384036","intensive-psychomotor-rehabilitation-on-cognitive-motor-abilities-and-adaptive-capacity-on-children-with-polyhandicap-100384036","NCT04280458","Intensive Psychomotor Rehabilitation on Cognitive Motor Abilities and Adaptive Capacity on Children With Polyhandicap","Impact of Intensive Psychomotor Rehabilitation on Cognitive-motor Abilities and Adaptive Capacity of Children With Polyhandicap","REEDUC-PLH","Inclusion Criteria:\n\n* Children between 4 and 13 years;\n* With polyhandicap defined by association of the 5 following criteria:\n\n  * Causal brain injury occurred before the age of 3 years\n  * Severe or deep mental deficiency as defined by IQ \\\u003C 40, or no evaluable by the psychometric tests\n  * Motor impairment: para \u002F tetraparesis, hemiparesis, ataxia, or extrapyramidal motor disorders\n  * Score of Gross Motor Function Classification System \\[Palisano 1997\\] is III, IV or V\n  * Score of Functional Independence Measure \\\u003C 50;\n* Hospitalization in a clinical setting participating to the study;\n* Beneficiary of a social protection;\n* Written consent signed by personnel holding parental authority or legal representative.\n\nExclusion Criteria:\n\n* Patient with progressive encephalopathies including metabolic origin, epileptic, or neurodegenerative diseases;\n* Planned to move in another clinical setting;\n* Foreseeable difficulty in the following up in the study.","4 Years","13 Years",{"count":50,"type":21},62,"INTERVENTIONAL",[53],"NA","Primary objective of the study is to compare and evaluate the impact of intensive care of rehabilitation of psychomotor vs. the standard care on adaptive behaviour of children with polyhandicap at 12 months after randomization.",[25],[57,58,59,60,61],"children polyhandicap","rehabilitation","psychomotor","cognitive-motor","adaptative skill","2025-03-17",{"date":64,"type":30},"2025-03-19",{"date":66,"type":30},"2022-06-20",{"date":68,"type":21},"2026-01",{"name":70,"class":37},"Assistance Publique - Hôpitaux de Paris",1]