[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-induction-hypotension-pih\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-induction-hypotension-pih":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100652642","carotid-doppler-changes-after-passive-leg-raising-for-prediction-of-post-induction-hypotension-in-gastrointestinal-tumor-surgery-100652642",false,"NCT07777159","Carotid Doppler Changes After Passive Leg Raising for Prediction of Post-Induction Hypotension in Gastrointestinal Tumor Surgery","Dynamic Changes in Carotid Artery Doppler Parameters Following Passive Leg Raising for Prediction of Post-Induction Hypotension in Patients Undergoing Elective Gastrointestinal Tumor Surgery","PLR","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Patients scheduled for elective gastrointestinal tumor surgery\n* Surgery planned under general anesthesia\n* Body mass index (BMI) \\\u003C40 kg\u002Fm²\n* Written informed consent provided\n\nExclusion Criteria:\n\n* Refusal to participate or inability to obtain written informed consent\n* BMI ≥40 kg\u002Fm²\n* Pregnancy\n* Emergency surgery\n* Difficult intubation\n* ASA physical status ≥IV\n* Pediatric patients (\\\u003C18 years)\n* Inability to perform carotid Doppler measurements\n* Arrhythmia other than continuous sinus rhythm or uncontrolled cardiac arrhythmia\n* Severe cardiac dysfunction or left ventricular ejection fraction \\\u003C40%\n* Severe valvular heart disease\n* Clinically significant autonomic nervous system disorders\n* Inadequate noninvasive blood pressure monitoring or inability to obtain the required hemodynamic measurements\n* Active sepsis or systemic inflammatory syndrome\n* Severe peripheral vascular disease or significant carotid artery stenosis (\\>50%)\n* Severe pulmonary disease or advanced respiratory failure\n* Implanted cardiac device (pacemaker\u002FICD)\n* Baseline mean arterial pressure (MAP) \\\u003C65 mmHg\n* Preoperative systolic blood pressure \\>190 mmHg or diastolic blood pressure \\>110 mmHg","ALL","18 Years",{"count":20,"type":21},99,"ESTIMATED","OBSERVATIONAL","This prospective study aims to investigate the role of the passive leg raise maneuver prior to anesthesia induction in predicting post-induction hypotension among elective gastrointestinal tumor surgery patients using carotid artery Doppler parameters.",[25,26],"Post-induction Hypotension (PIH)","Gastrointestinal Tumor Surgery",[28,29,30,31],"Carotid Doppler","Passive Leg Raise","Post-induction Hypotension","Anesthesia İnduction","NOT_YET_RECRUITING","2026-08-17",{"date":35,"type":36},"2026-08-20","ACTUAL",{"date":38,"type":21},"2026-09-01",{"date":40,"type":21},"2026-12",{"name":42,"class":43},"Ankara City Hospital Bilkent","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":55,"conditions":56,"keywords":61,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":44},"100615548","incidence-and-risk-factors-of-post-induction-hypotension-in-geriatric-cancer-patients-100615548","NCT07294040","Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients","A Prospective Observational Study to Determine the Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Oncologic Patients Undergoing General Anesthesia at a Tertiary Oncology Center","Inclusion Criteria:\n\n* Adults ≥65 years of age\n\nPatients with a diagnosis of cancer and scheduled for surgery\n\nAbility and willingness to provide written informed consent\n\nASA physical status class II-IV\n\nExclusion Criteria:\n\nPatients under 65 years of age\n\nPatients without a confirmed oncologic diagnosis\n\nRefusal to provide written informed consent\n\nPatients undergoing regional anesthesia\n\nPatients with tracheostomy or requiring multiple intubation attempts\n\nHistory of peripheral arterial disease\n\nUse of vasopressors before the start of surgery\n\nUncontrolled hypertension (blood pressure \\>180\u002F110 mmHg)\n\nAdvanced heart failure (Ejection Fraction \\\u003C40%)\n\nSevere arrhythmias such as atrial fibrillation or significant ventricular arrhythmias that preclude reliable hemodynamic monitoring","65 Years",{"count":54,"type":21},140,"This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia. PIH is defined as a drop in mean arterial pressure of ≥30% from baseline or below 65 mmHg within the first 20 minutes after anesthesia induction, prior to surgical stimulation.\n\nThe primary objective is to determine the frequency of PIH in elderly oncology patients. Secondary objectives include evaluating the association of PIH with age, ASA score, cancer type, oncological treatments (chemotherapy\u002Fradiotherapy), comorbidities, medication use, anemia, biochemical parameters, and preoperative perfusion index (PI) and pleth variability index (PVI).\n\nFindings from this study are expected to contribute to improved perioperative management and to the development of tailored anesthesia protocols for geriatric oncology patients.",[25,57,58,59,60],"Geriatric Patient","Oncologic Disease","Hemodynamic Effects of General Anesthesia","Risk Factors Associated With Anesthesia-Induced Hypotension",[30,62,63,64,65,66,67],"Perfusion Index (PI)","Pleth Variability Index (PVI)","geriatric patient","Oncologic Patients","General Anesthesia","Hemodynamics","RECRUITING","2025-12-07",{"date":71,"type":36},"2025-12-19",{"date":73,"type":36},"2025-05-25",{"date":75,"type":21},"2026-05-25",{"name":77,"class":43},"Dolunay ARIK"]