[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-operative-inflammatory-marker-levels\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-operative-inflammatory-marker-levels":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100654694","effect-of-intravenous-magnesium-on-postoperative-systemic-inflammatory-response-in-patients-undergoing-colorectal-cancer-surgery-100654694",false,"NCT07803601","Effect of Intravenous Magnesium on Postoperative Systemic Inflammatory Response in Patients Undergoing Colorectal Cancer Surgery","Inclusion Criteria:\n\n* ASA I and ASA II.\n* Age (35yrs - 75yrs).\n* Patients undergoing open colorectal cancer surgery.\n* Sex: Both sexes.\n\nExclusion Criteria:\n\n* Renal impairment (Glomerular Filtration Rate \\\u003C 60 ml\\\\min).\n* Severe cardiac dysfunction (Ejection fraction ≤ 30% or clinical signs and symptoms of reduced left ventricular ejection fraction), preoperative bradycardia (HR \\\u003C 50 bpm) and atrioventricular block (first, second and third degree).\n* Allergy to study drug (MgSO4).\n* Patient refusal to precipitate in this study.\n* Autoimmune disorders (eg: rheumatoid arthritis, multiple sclerosis and lupus), congenital and acquired immunodeficiency.\n* Previous \u002F current immunomodulatory therapy.\n* Emergency condition (eg: obstruction or perforation in colorectal cancer).\n* Postoperative complications altering inflammatory response (eg: infection, anastomotic leak).\n* Duration of operation \\> 5 hours.\n* Cognitive impairment (eg: Dementia) and other psychiatric disorders by history.\n* Body mass index less than 18 or greater than 30 kg\u002Fm².","ALL","35 Years","75 Years",{"count":19,"type":20},52,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim of this study is to detect the effect of intraoperative intravenous magnesium sulfate on postoperative systemic inflammatory response by serum inflammatory parameters as CRP, WBCS and neutrophil count.",[26,27],"Post Operative Inflammatory Marker Levels","Post Operative Pain","RECRUITING","2026-09-02",{"date":31,"type":32},"2026-09-03","ACTUAL",{"date":34,"type":32},"2026-03-01",{"date":36,"type":20},"2027-04-01",{"name":38,"class":39},"Ain Shams University","OTHER"]