[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"posterior-tibial-tendon-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:posterior-tibial-tendon-dysfunction":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100650691","blood-flow-restriction-training-in-women-with-posterior-tibial-tendon-dysfunction-100650691",false,"NCT07750106","Blood Flow Restriction Training in Women With Posterior Tibial Tendon Dysfunction","Effects of Blood Flow Restriction Training on Dynamic Postural Stability and Proprioception in Post-Menopausal Women With Posterior Tibial Tendon Dysfunction: A Randomized Controlled Trial","BFR-PTTD","Inclusion Criteria:\n\n* Female post-menopausal women aged 40-55 years.\n* Clinically diagnosed with Stage I or flexible Stage II posterior tibial tendon dysfunction according to the Johnson and Strom classification modified by Myerson confirmed by an orthopedic physician.\n* Symptoms persisting for ≥ 3 months.\n* Pain intensity of ≥3\u002F10 on the Visual Analogue Scale (VAS) during weight-bearing activities.\n* Medically cleared to participate in blood flow restriction resistance training.\n* Symptoms located at the medial ankle or foot.\n* Pain on palpation of the posterior tibial tendon.\n* A positive double and\u002For single heel-rise test.\n* Able to walk independently without assistive devices\n* Body Mass Index (BMI) between 18.5 and \\\u003C24.9 kg\u002Fm².\n* Willingness to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Rigidity of the hindfoot.\n* Pain on palpation of the fibular muscles.\n* History of corticosteroid injection in the tendon in a one-month period prior to the study onset.\n* History of surgery to the hindfoot and\u002For ankle.\n* History of previous surgeries to the musculoskeletal structures (i.e., bones, joint structures, nerves) in either limb of the lower extremities.\n* History of a fracture in either limb of the lower extremities requiring realignment.\n* Acute injury to musculoskeletal structures of other joints of the lower extremity in the previous three months, which impacted joint integrity and function (i.e., sprains, fractures) resulting in interruption of desired physical activity.\n* Hip joint or knee joint replacement.\n* Patients who were possibly at risk of adverse reactions of blood flow restriction (i.e., poor circulatory system, obesity, diabetes, arterial calcification, sickle cell trait, severe hypertension, or renal failure).\n* Any neurological conditions that affect proprioception, such as polyneuropathy, multiple sclerosis, and sensory ataxia.\n* Vestibular deficits and vision problems.","FEMALE","40 Years","55 Years",{"count":21,"type":22},54,"ESTIMATED","INTERVENTIONAL",[25],"NA","Posterior tibial tendon dysfunction (PTTD) is a common musculoskeletal disorder characterized by pain, impaired foot function, and reduced dynamic stability. As one of the primary causes of adult-acquired flatfoot deformity, it can significantly affect walking ability, balance, and overall performance of daily activities. Although conventional rehabilitation typically emphasizes strengthening the posterior tibial tendon and surrounding muscles, these interventions may not fully address deficits in neuromuscular control and postural stability, highlighting the need for additional therapeutic approaches.\n\nThis randomized controlled trial aims to evaluate whether incorporating blood flow restriction (BFR) training into a rehabilitation program provides additional benefits for postmenopausal women with Stage I or flexible Stage II PTTD. A total of 54 eligible participants will be randomly allocated to either a BFR training group or a conventional exercise group. Clinical outcomes will be assessed before and after the intervention, including dynamic postural stability measured with the Biodex Balance System and active and passive ankle joint position sense assessed using the Biodex Isokinetic Dynamometer.",[28],"Posterior Tibial Tendon Dysfunction",[28,30],"Blood Flow Restriction","NOT_YET_RECRUITING","2026-08-01",{"date":34,"type":35},"2026-08-06","ACTUAL",{"date":32,"type":22},{"date":38,"type":22},"2026-10-01",{"name":40,"class":41},"May University in Cairo","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":42},"100536129","biomechanical-and-morphological-characterization-of-pttd-100536129","NCT06260813","Biomechanical and Morphological Characterization of PTTD","Biomechanical and Morphological Characterization of the Foot in Patients With Posterior Tibial Tendon Dysfunction.","PTTD","Inclusion criteria:\n\n* Patient groups:\n\n  * Posterior tibial tendon dysfunction (all clinical stages)\n  * Age 18-675 year\n  * ICF obtained\n* Control group:\n\n  * No pain complaints\n  * No pes plano valgus, PTTD or pes cavo varus or other foot and ankle pathology\n  * Age 18-75 year\n  * ICF obtained\n\nExclusion criteria patient and control groups:\n\n* Being younger than 18 years\n* Inability to walk without mobility aids\n* Inability to walk \\\u003C 100 meter\n* Difference in leg length \\> 3cm\n* Subjects with BMI\\>30 kg\u002Fm², due to less accurate gait analysis by absence of anatomical landmarks\n* Subjects unable to perform a gait analysis\n* Any medical condition possibly affecting normal gait.\n* Pregnancy: at the start or during the study",true,"ALL","18 Years","75 Years",{"count":56,"type":22},100,[25],"Posterior tibial tendon dysfunction (PTTD) is a progressive condition of the tendon of the tibialis posterior muscle with symptoms of tendinopathy or even rupture. Functionally, it is associated with the inability to lock the mid foot and thus manifests itself as a main contributor to adult acquired flatfoot deformity.\n\nConcerning treatment, clinical decision making is currently based on a classification integrating various parameters as pain, flexibility of the foot joints, the condition of the posterior tibial tendon assessed through ultrasound imaging and radiographic assessment of arthritic changes. Surprisingly, this classification does not consider any morphologic characteristics (the shape of a bone or joint) or functional, biomechanical characteristics of the foot and ankle, i.e. based on kinematics (e.g. range of motion) and\u002For kinetics (center of pressure, angular velocity, moment, power absorption and power generation of a joint).\n\nDetailed biomechanical characteristics of the foot and ankle can be reliably collected by instrumented gait analysis wherein a 3D camera system is combined with a force plate and plantar pressure platform. Kinematic studies in the field of PTTD typically considered the foot as a structure consisting of three segments: hind foot, forefoot and hallux. Consequently, the mid foot segment (the Chopart and Lisfranc joints) has been neglected, although it is this segment that is particularly affected in PTTD patients.\n\nThe aim of this research is to overcome the limitations of the current classification system and treatment of PTTD patients, by complementing the current standard-of-care clinical assessment with better insight in the pathologic changes that occur in PTTD patients.",[28],"RECRUITING","2026-07-09",{"date":63,"type":35},"2026-07-10",{"date":65,"type":35},"2022-08-22",{"date":67,"type":22},"2028-08-01",{"name":69,"class":41},"Universitaire Ziekenhuizen KU Leuven",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":52,"minAge":53,"maxAge":78,"enrollmentInfo":79,"targetDuration":4,"studyType":23,"phases":81,"briefSummary":82,"conditions":83,"keywords":86,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":106},"100611187","peripheral-magnetic-stimulation-of-foot-muscles-effects-on-medial-longitudinal-arch-height-and-foot-muscle-strength-in-adults-with-flat-feet-100611187","NCT07237321","Peripheral Magnetic Stimulation of Foot Muscles: Effects on Medial Longitudinal Arch Height and Foot Muscle Strength in Adults With Flat Feet","Peripheral Magnetic Stimulation of Foot Muscles","rPMS-Foot","Inclusion Criteria:\n\n* Age between 18 and 50 years,\n* functionally flat feet of participants.\n\nExclusion Criteria:\n\n* Acute leg injuries,\n* diabetes,\n* vascular disorders of the lower limbs,\n* open wounds or skin lesions on the lower leg or foot,\n* participants with metal implants near the stimulation site,\n* cardiac pacemaker,\n* other orthopedic or neurological conditions that could affect the study results or pose a health risk to the participants.","50 Years",{"count":80,"type":22},30,[25],"This study examines the effects of repetitive peripheral magnetic stimulation (rPMS) on foot invertor muscle strength, morphology, and the height of the medial longitudinal arch (MLA) in individuals with flat feet. The rPMS will be applied non-invasively to the extrinsic and intrinsic foot muscles three times per week for twelve weeks. The experimental group will receive rPMS targeting the invertor muscles of the foot, while the control group will not receive stimulation but will follow the same measurement schedule.\n\nAssessments will be performed at baseline, after 6 weeks, and after 12 weeks of intervention. The primary outcome will be the change in the height of the MLA, evaluated using dynamic navicular drop assessment during gait. Secondary outcomes will include changes in the isometric inversion torque of the foot invertors and morphological adaptations of the tibialis posterior muscle assessed by ultrasound imaging.\n\nThis study seeks to determine whether rPMS can improve the height of the MLA, foot invertor muscle strength and structural stability in adults with flat feet. The findings may contribute to developing new, non-invasive therapeutic approaches for improving foot function and preventing musculoskeletal imbalances related to flat foot deformity.",[84,85,28],"Pes Planus","Flatfoot",[87,85,88,89,90,91,92,93,94,95,96],"Medial Longitudinal Arch","rPMS","foot invertors","tibialis posterior","repetitive peripheral magnetic stimulation","foot","posterior tibial tendon dysfunction","strength","ultrasound","muscle cross-sectional area","2026-05-30",{"date":99,"type":35},"2026-06-02",{"date":101,"type":35},"2025-12-16",{"date":103,"type":22},"2027-12-31",{"name":105,"class":41},"University of Ljubljana",2]