[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-complication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-complication":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,48,78,107,140,173,207,232],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100650591","zepu-ai9-exoskeleton-rehabilitation-robot-100650591",false,"NCT07750808","ZEPU AI9 Exoskeleton Rehabilitation Robot","Feasibility, Safety and Efficacy of ZEPU AI9 Lower Limb Exoskeleton Rehabilitation Robot in Patients With Lower Limb Motor Dysfunction","Inclusion Criteria:\n\n* Age ≥ 18 and ≤ 60 years.\n* Lower-limb motor dysfunction from one of the following: (a) stroke (onset 2-24 months), (b) incomplete spinal-cord injury (neurological level T12 and below, ASIA C or D), (c) orthopedic surgery (e.g., knee\u002Fhip replacement) with persistent gait impairment \\> 3months post-surgery.\n* Able to provide informed consent and understand instructions.\n* Weight ≤ 100 kg (as per device spec) and height within device adjustable range (manufacturer spec).\n* Medically stable and cleared by physician for exoskeleton use (no active infection, uncontrolled cardiac\u002Frespiratory disease, severe osteoporosis, uncontrolled epilepsy, untreated DVT) with necessary investigations.\n\nExclusion Criteria:\n\n* Complete spinal cord injury with inability to bear any weight.\n* Severe cognitive impairment (e.g., MMSE \\\u003C 24) preventing safe participation.\n* Severe spasticity (Modified Ashworth Scale \\> 3) in lower limbs.\n* Unstable fractures, severe hip\u002Fknee contractures (\\> 30° fixed flexion), severe osteoarthritis requiring imminent surgery.\n* Uncontrolled cardiac arrhythmia, pacemaker incompatibility, or implanted electronic device incompatible with robot sensors.\n* Pregnancy.","ALL","18 Years","60 Years",{"count":20,"type":21},36,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn whether the ZEPU AI9 lower limb exoskeleton robot is feasible, safe, and effective for people with walking difficulty caused by stroke, incomplete spinal cord injury, or orthopedic surgery. The main questions it aims to answer are:\n\nIs exoskeleton-assisted gait training well tolerated, and how often do device-related problems (such as falls, pain, or skin injury) occur? Does adding exoskeleton training to usual rehabilitation improve walking distance, walking speed, balance, muscle strength, and joint movement compared with usual rehabilitation alone? Is it practical to add this robotic training into the rehabilitation program at Bangladesh Medical University?\n\nResearchers will compare a group receiving exoskeleton-assisted gait training plus standard rehabilitation to a group receiving standard rehabilitation alone, to see whether the exoskeleton adds benefit.\n\nParticipants will:\n\nBe randomly assigned to either the exoskeleton group or the standard-care group If assigned to the exoskeleton group, attend 45-minute training sessions 3 times a week for 12 weeks, supervised by physical therapists with safety harness support Both groups will continue their usual rehabilitation therapy throughout the study Undergo walking, balance, strength, and quality-of-life assessments at the start of the study and every 2 weeks for 12 weeks Be monitored for any side effects or safety concerns during and after each session",[27,28,29,30],"Stroke","Gait Disorders, Neurologic","Spinal Cord Injuries, Incomplete","Postoperative Complication",[32,33,34],"Lower limb exoskeleton","Robotic Rehabilitation","Neurorehabilitation","NOT_YET_RECRUITING","2026-08-06",{"date":38,"type":39},"2026-08-10","ACTUAL",{"date":41,"type":21},"2026-08",{"date":43,"type":21},"2026-12",{"name":45,"class":46},"Bangladesh Medical University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":69,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":77},"100567968","assessment-of-the-impact-of-intestinal-gas-emission-quality-on-the-postoperative-course-after-abdominal-surgery-100567968","NCT06675097","Assessment of the Impact of Intestinal Gas Emission Quality on the Postoperative Course After Abdominal Surgery","Assessment of the Impact of Intestinal Gas Emission Quality on the Postoperative Course After Abdominal Surgery: Multicentric-center Prospective Study - FLATQUAL- Abdominal Surgery and Gas Transit","FLATQUAL","Inclusion Criteria:\n\n* Patients ≥18 years old\n* Indication for open or laparoscopic abdominal surgery\n* Whose expected length of stay is ≥ 2 days\n\nNon Inclusion Criteria:\n\n* Patients requiring a stomy on the initial surgery\n* Emergency surgery\n* Patient not knowing how to read or write\n* Poor understanding of the French language\n* Person deprived of liberty by judicial or administrative decision\n* Person subject to psychiatric care under duress\n* Person subject to a legal protection measure\n* Person unable to express consent\n* Person objecting to participating in research\n\nExclusion Criteria:\n\n-Immediate post-operative intensive care with patient intubation",{"count":57,"type":21},200,"OBSERVATIONAL","The recovery of transit after surgery is an important parameter in postoperative evaluation. It generally reflects simple postoperative outcomes and allows the patient to return home.\n\nThe quality of gas recovery after surgery has not been studied to our knowledge, but it is not uncommon for an operated patient to emit some gas considered as a recovery of transit when it is ultimately a false transit preceding a postoperative ileus. Furthermore, intestinal gases and their composition reflect the intestinal microbiota. This microbiota has been shown to be predictive of the appearance of an operative complication. As the analysis of this microbiota cannot be carried out routinely, it is important to be able to use a reflection of this microbiota in routine practice and to correlate it with the surgical outcomes. Intestinal gas therefore seems to be the tool of choice.\n\nThe main objective is to evaluate the association between the appearance of an operative complication and the resumption of gas transit qualified according to its quantity and quality.\n\nThe secondary objectives are to compare the quantity and quality of gases pre- and post-operatively and to define a predictive score for surgical complications, based on the number and quality of post-surgical gases.\n\nData regarding gas transit are collected by the patient in a questionnaire the two days before the surgery and until the patient leaves hospital (or until day 15 post-operative if the patient is still hospitalized).\n\nData regarding possible complications ((defined according to Dindo-Clavien as any deviation from the expected postoperative outcomes within 90 days following surgery) are collected throughout the hospital stay (day 0 : surgery to day 15 post-operatively), during the post-operative consultation (day 30) and during a telephone call to the patient (day 90).\n\nThe expected results are to highlight a correlation between the quality\u002Fquantity of gases and post-operative outcomes. A predictive score for complications could then be proposed and validated during this study.",[30,61],"Recovery, Physiological",[63,64,65,66,67],"transit","surgery","abdomen","stool","gas","RECRUITING",{"date":38,"type":39},{"date":71,"type":39},"2025-01-31",{"date":73,"type":21},"2027-04",{"name":75,"class":76},"University Hospital, Angers","OTHER_GOV",2,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":87,"conditions":88,"keywords":93,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":47},"100617905","impact-of-intraoperative-hemodynamic-instability-on-outcomes-in-cardiac-surgery-100617905","NCT07324694","Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery","Impact of Intraoperative Hemodynamic Instability on Postoperative Major Adverse Events in Cardiac Surgery Patients: A Prospective Cohort Study","Inclusion Criteria:\n\n* Patients aged 18 years or older.\n* Scheduled for elective cardiac surgery (CABG, Valve replacement\u002Frepair, or combined procedures).\n* Surgery performed under cardiopulmonary bypass (CPB).\n* Preoperative sinus rhythm.\n* Signed informed consent form.\n\nExclusion Criteria:\n\n* Emergency or salvage surgery.\n* Off-pump coronary artery bypass grafting.\n* Preoperative mechanical circulatory support (IABP, ECMO) requirement.\n* Pre-existing chronic renal failure requiring dialysis (HD\u002FPD).\n* Pre-existing cognitive impairment, dementia, or history of psychiatric disorders affecting cooperation.\n* Pregnancy.",{"count":86,"type":21},230,"Intraoperative hemodynamic instability (IOHI) is a common occurrence during cardiac surgery and is associated with organ hypoperfusion. However, the specific impact of IOHI on composite adverse outcomes remains unclear. This prospective cohort study aims to evaluate the association between intraoperative hemodynamic instability (defined as MAP \\\u003C 65 mmHg or vasopressor requirement) and major postoperative complications (Delirium, Acute Kidney Injury, Stroke, or Mortality) in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass.",[89,90,30,91,92],"Cardiac Surgery","Intraoperative Hemodynamic Instability","Acute Kidney Injury","Postoperative Delirium (POD)",[94,95,96,97],"Intraoperative Hypotension","Cardiopulmonary Bypass","Mean Arterial Pressure","Cohort Study","2026-07-28",{"date":100,"type":39},"2026-07-29",{"date":102,"type":39},"2025-04-26",{"date":104,"type":21},"2026-09-05",{"name":106,"class":46},"Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":113,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":115,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":117,"conditions":118,"keywords":121,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":47},"100649145","real-time-evaluation-and-continuous-observation-of-vital-signs-for-enhanced-recovery-a-study-for-the-early-identification-of-complications-in-the-surgical-ward-following-surgery-in-patients-not-eligible-for-intensive-care-admission-100649145","NCT07729891","Real-time Evaluation and Continuous Observation of Vital Signs for Enhanced Recovery: a Study for the Early Identification of Complications in the Surgical Ward Following Surgery in Patients Not Eligible for Intensive Care Admission.","Real-time Evaluation and Continuous Observation of Vital Signs for Enhanced Recovery","RECOVER","Inclusion Criteria:\n\n* Ability to give informed consent and consent to the processing of personal data by signing the relevant forms;\n* Aged over 18 years old\n* Medium-to-high complexity urological surgery without the need for post-operative monitoring in the Intensive Care Unit\n* Surgery performed under general anaesthesia\n* Discharge to the ward is scheduled upon leaving the operating theatre\n\nExclusion Criteria:\n\n* Refusal or inability to consent to participation\n* Patients under 18 years old\n* Planned admission to Post-Operative Intensive Care Unit after the surgery\n* Unplanned admission to the Post-Operative Intensive Care Unit at the end of the surgery\n* Anaesthetic technique other than general anaesthesia.",{"count":116,"type":21},150,"This study aims to evaluate whether continuous vital sign monitoring with wearable devices can help detect postoperative complications in surgical ward earlier than standard hospital monitoring. In particular, the goal of this observational study is to evaluate if the wireless wearable devices Portrait Mobile (GE Healthcare) can detect early signs of complications after major urologic surgery in adults who are not eligible for intensive care unit admission. The main questions it aims to answer are:\n\n* Can continuous monitoring of vital signs (heart rate, breathing rate, blood oxygen) detect health problems earlier than standard nurse checks in the urology ward?\n* How many times do participants' vital signs change in ways that suggest a complication is developing during the first days after surgery?\n* Does the vital sign trend and\u002For the deviation from patients' baseline suggest a complication is developing during the first days after surgery?\n* Does continuous monitoring help healthcare providers intervene before patients become critically ill thus reducing complications burden or severity and reducing unplanned intensive care admission? Participants in the intervention cohort will wear a wireless patch-like device on their chest that continuously tracks their heart rate, breathing rate, and blood oxygen levels. The device sends this information to hospital staff through a secure wireless connection while participants recover in the regular urology ward after surgery. Participants in the intervention cohort will wear the device for 3 days after surgery or until they leave the hospital. Healthcare providers will receive alerts if vital signs change in ways that suggest a complication may be developing. This may help providers treat problems earlier and prevent patients from becoming critically ill. All participants will also receive standard post-surgical care, including regular nurse checks of vital signs.",[30,119,120],"Respiratory Complications","Cardiac Complications",[122,123,124,125,126,127,128,129,130,131],"postoperative","complications","intensive care unit admission","urology","wearable devices","continuous monitoring","surgical ward","wireless","medical emergency team","unplanned ICU admission","2026-07-22",{"date":98,"type":39},{"date":135,"type":39},"2026-02-10",{"date":137,"type":21},"2027-02",{"name":139,"class":46},"Azienda Ospedaliero-Universitaria di Parma",{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":146,"eligibilityCriteria":147,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":148,"enrollmentInfo":149,"targetDuration":4,"studyType":22,"phases":151,"briefSummary":152,"conditions":153,"keywords":157,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":4},"100631119","the-acure-trial-acupuncture-for-colorectal-recovery-100631119","NCT07496528","The ACURE Trial: Acupuncture for Colorectal Recovery","Acupuncture for Colorectal sUrgery Recovery Enhancement: A Randomized Controlled Trial Evaluating Gastrointestinal Functional Recovery After Minimally Invasive Resection","ACURE","Inclusion Criteria:\n\n* Histologically confirmed colorectal cancer requiring scheduled curative-intent resection.\n* Age between 18 and 79 years, inclusive.\n* Ability to understand the study protocol and provide written informed consent.\n* American Society of Anesthesiologists (ASA) physical status classification of I, II, or III.\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women.\n* History of major abdominal surgery within the past 4 weeks.\n* Receipt of chemotherapy or radiotherapy within the past 6 months.\n* History of organ transplantation with rejection episodes within the past 30 days.\n* Presence of active infection (e.g., tuberculosis, sepsis, peritonitis).\n* Positive for hepatitis B, hepatitis C, or HIV with an uncontrolled viral load.\n* Severe malnutrition, defined as a Nutritional Risk Screening (NRS 2002) score ≥ 3.\n* History of total colectomy or requirement for ileorectal anastomosis.\n* Requirement for multivisceral resection due to tumor invasion.\n* Scheduled for prophylactic stoma creation.\n* Moderate to severe cognitive impairment, epilepsy, or uncontrolled neurological disorders.\n* Active psychiatric illness (e.g., bipolar disorder, schizophrenia) that may interfere with study compliance.\n* Severe cardiopulmonary insufficiency (e.g., New York Heart Association \\[NYHA\\] class IV heart failure or requirement for long-term oxygen therapy).\n* Presence of open wounds, skin infections, or known allergies at or near the designated acupuncture sites.\n\nHistory of adverse reactions to acupuncture, including syncope (fainting) or needle phobia.\n\nParticipation in another clinical trial within the past 6 months.\n\nAnticipated inability to complete the study protocol due to physical, psychological, or logistical reasons.","80 Years",{"count":150,"type":21},240,[24],"Purpose:\n\nThe goal of this clinical trial is to evaluate whether electroacupuncture (EA) can accelerate the recovery of bowel function in patients undergoing minimally invasive surgery for colorectal cancer.\n\nMain Questions to be Answered:\n\nDoes electroacupuncture reduce the time to the first bowel movement after surgery compared to standard care or a \"sham\" (placebo) treatment?\n\nCan electroacupuncture improve overall gastrointestinal tolerance and reduce postoperative discomfort?\n\nStudy Design:\n\nParticipants will be randomly assigned to one of three groups:\n\nElectroacupuncture Group: Receives active electrical stimulation at specific acupuncture points.\n\nSham Acupuncture Group: Receives superficial needling at non-treatment points with no electrical current to serve as a placebo.\n\nStandard Care Group: Receives standard hospital recovery protocols (ERAS) without acupuncture.\n\nAll treatments will consist of four 30-minute sessions: one before surgery and three on the days following the procedure. Researchers will compare the three groups to see if the electroacupuncture group experiences a faster return of digestive function.",[154,155,30,156],"Colorectal Neoplasms","Ileus Postoperative","Gastrointestinal Motility",[158,159,160,161,162,163],"electroacupuncture","acupuncture therapy","colorectal cancer","enhanced recovery after surgery","minimally invasive surgery","postoperative ileus","2026-03-31",{"date":166,"type":39},"2026-04-06",{"date":168,"type":21},"2026-04-01",{"date":170,"type":21},"2029-05-31",{"name":172,"class":46},"Chang Gung Memorial Hospital",{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":4,"eligibilityCriteria":179,"healthyVolunteers":180,"sex":16,"minAge":181,"maxAge":4,"enrollmentInfo":182,"targetDuration":184,"studyType":58,"phases":4,"briefSummary":185,"conditions":186,"keywords":191,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":198,"lastUpdatePostDateStruct":199,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":47},"100627717","modified-essential-frailty-toolset-in-older-adults-undergoing-major-elective-surgery-100627717","NCT07452263","Modified Essential Frailty Toolset in Older Adults Undergoing Major Elective Surgery","Modified Essential Frailty Toolset for Predicting Postoperative Complications and Readmission in Older Adults Undergoing Major Elective Surgery","Inclusion Criteria:\n\n* Patients ≥ 70 years who present for preoperative work-up at the admissions department at Landspitali and undergo frailty screening.\n* Patients assigned to undergo major surgery\n\nExclusion Criteria:\n\n* Cardiac surgery\n* Not undergoing planned surgery",true,"70 Years",{"count":183,"type":21},250,"6 Months","Frailty is a common geriatric syndrome associated with reduced physiological reserve and increased vulnerability to surgical stress. As the population ages, more older adults undergo major elective surgery, yet frailty is often insufficiently assessed in routine practice and no universally accepted screening tool exists.\n\nThe Essential Frailty Toolset (EFT) is a simple validated frailty assessments and has demonstrated strong predictive value for mortality and major postoperative complications, particularly in cardiac surgery populations. EFT incorporates four key domains of cognition, anemia, serum albumin, and physical function capturing both physical and cognitive vulnerability. A modified version (mEFT) has been developed to improve feasibility and applicability in broader surgical settings, requiring minimal training and only a few minutes to administer. Despite its promise, mEFT has not been evaluated in elderly patients undergoing major elective non-cardiac surgery, representing an important gap in the current literature and motivating the present study.\n\nWe therefore propose a modified and simplified frailty screening tool tailored for elderly patients undergoing major elective non-cardiac surgery at our institution. The modified Essential Frailty Toolset (mEFT) is a multi-dimensional assessment designed to address this gap by evaluating physical function, cognition, nutrition, and anemia in just a few minutes. In this version, the tool assigns points based on specific clinical markers: the Timed Up and Go (TUG) test provides one point for a time ≥11.0 seconds and two points for ≥15.0 seconds; the Clock Drawing Test (CDT) provides one point for a score of ≤2 on a 3-point scale; nutritional risk is captured with one point for a BMI \\\u003C22.0 or unintentional weight loss of 5% over the last six months; and anemia provides one point based on hemoglobin levels (below 130g\u002FL for men and 120 g\u002FL for women). These modifications were made to enhance feasibility and clinical relevance in our population. Low serum albumin was rare in our cohort and therefore demonstrated limited discriminatory value as a screening marker. In contrast, low BMI and recent weight loss are well-established risk factors for malnutrition and sarcopenia and are readily obtainable in routine preoperative assessment. Similarly, both the TUG and CDT are quick, inexpensive, and require minimal training, making them well suited for large-scale screening in preoperative clinics.Importantly, the proposed components have been evaluated in a pilot study conducted in our institution.\n\nThis study will evaluate whether a high mEFT score (≥3) is associated with increased postoperative complications and 90-day readmissions among patients aged ≥70 years undergoing major elective surgery. Patients presenting for admission will be included. If mEFT accurately identifies high-risk patients, it may improve preoperative risk stratification, inform shared decision-making, and help identify individuals who could benefit from targeted prehabilitation, supporting broader implementation of frailty screening in surgical care.",[187,188,189,190,30],"Frailty in Adult Surgery","Frailty Syndrome","Elective Surgeries","Readmission Rates",[192,193,194,195,196,197],"Frailty","Postoperative Outcomes","Major elective surgery","Surgical Frailty","Readmission","Complications","2026-03-06",{"date":200,"type":39},"2026-03-10",{"date":202,"type":39},"2025-01-20",{"date":204,"type":21},"2026-12-31",{"name":206,"class":46},"University of Iceland",{"id":208,"slug":209,"hasResults":11,"nctId":210,"briefTitle":211,"officialTitle":211,"acronym":4,"eligibilityCriteria":212,"healthyVolunteers":11,"sex":16,"minAge":213,"maxAge":18,"enrollmentInfo":214,"targetDuration":4,"studyType":22,"phases":216,"briefSummary":217,"conditions":218,"keywords":221,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":4},"100590823","comparison-of-endodontic-flare-up-in-single-visit-root-canal-treatment-versus-multiple-visit-root-canal-treatment-in-patients-visiting-scd-swat-100590823","NCT06972433","Comparison of Endodontic Flare up in Single Visit Root Canal Treatment Versus Multiple Visit Root Canal Treatment in Patients Visiting Scd, Swat.","Inclusion Criteria:\n\n* Children in the age group \\>10 years with deep caries approximating pulp on radiograph and indicated for a root canal treatment.\n* Proper bone support.\n* No evidence of severe mobility\u002Fdischarge of frank pus\n* Radiographically tooth indicated for root canal treatment.\n* Permanent first molars with periapical radiolucency not exceeding 3 mm × 3 mm in size.\n* Complete root formation.\n* Teeth in which the initial master file (K-File)binds at the apex were of ISO size 45 or less.\n\nExclusion Criteria:\n\n* Tooth\u002Fteeth with extensive periodontal pathology\u002F periapical radiolucency.\n* Teeth with evidence of internal or external root resorption involving more than one third of the root length.\n* Children with facial cellulitis or significant extraoral swelling.\n* Patients with any systemic diseases.\n* Patients who had been taking Antibiotics ,nonsteroidal anti-inflammatory drugs, corticosteroids at time of treatment.\n* Pregnant patients","10 Years",{"count":215,"type":21},344,[24],"This randomized controlled trial aims to compare the incidence of endodontic flare-ups in patients undergoing single-visit versus multiple-visit root canal treatment (RCT) at Saidu College of Dentistry, Swat. The study will recruit 344 patients aged above 10 and below 60 years, with permanent first molars indicated for RCT and meeting specific clinical and radiographic criteria. Participants will be randomly allocated into two groups: one receiving single-visit RCT and the other receiving multiple-visit RCT. Pain and flare-up incidence will be evaluated using the Visual Analog Scale (VAS) and swelling grading criteria at 6, 24, and 48 hours post-treatment. The primary outcome is the frequency of endodontic flare-ups requiring additional intervention. The study also examines the role of occlusal reduction in managing postoperative discomfort. Data will be analyzed using SPSS v23 with chi-square and Fisher's exact tests to compare outcomes. The findings aim to inform evidence-based protocols for endodontic treatment in the local population.",[30,219,220],"Root Canal Therapy","Pulpitis - Irreversible",[222],"enddoontic flare-ups, root canal therapy, single visit root canal treatment, multiple visit root canal treatment","2025-05-13",{"date":225,"type":39},"2025-05-15",{"date":227,"type":21},"2026-01-01",{"date":229,"type":21},"2026-06-30",{"name":231,"class":46},"College of Physicians and Surgeons Pakistan",{"id":233,"slug":234,"hasResults":11,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":238,"eligibilityCriteria":239,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":240,"targetDuration":242,"studyType":58,"phases":4,"briefSummary":243,"conditions":244,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":255,"completionDateStruct":257,"leadSponsor":259,"locationsCount":77},"100565166","prolonged-hospital-stay-after-thoracoscopic-anatomical-lung-resections-100565166","NCT06638645","Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections","Reasons for Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections","PROTRACT","Inclusion Criteria:\n\n* Patients referred for elective minimally invasive (uniportal or multiportal video- or robot-assisted) anatomical lung resection (lobectomy or segmentectomy)\n* Informed consent obtained pre-operatively\n* Age 18 years or older\n\nExclusion Criteria:\n\n* Patients younger than 18 years old\n* Traumatic event as indication for lung resection\n* Non-anatomical lung resections\n* Thoracotomy\n* Patients already hospitalized for other pathologies, pre-existent and not related to the lung surgery\n* Urgent\u002Femergency procedures",{"count":241,"type":21},140,"2 Months","In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated. Currently, whenever possible, these anatomical lung resections are performed thoracoscopically, as they offer significant improvements in terms of postoperative pain, number of postoperative complications, rehabilitation, tolerance for adjuvant chemotherapy, and length of hospital stay. The development of an 'Enhanced Recovery After Surgery' (ERAS) protocol for lung surgery has further reduced hospital stay and the need for opioids for analgesia. Despite the optimal implementation of the ERAS protocol, there are still patients who need to stay in the hospital longer than the median. The aim of this research is to investigate the reasons for this.",[245,246,247,248,249,250,30,251],"Minimally Invasive Surgical Procedures","VATS","RATS Surgery","Pulmonary Lobectomy","Pulmonary Segmentectomy","Air Leakage","Pain Postoperative","2025-01-13",{"date":254,"type":39},"2025-01-15",{"date":256,"type":39},"2024-11-12",{"date":258,"type":21},"2025-12-31",{"name":260,"class":46},"University Hospital, Ghent"]