[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"postoperative-rehabilitation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:postoperative-rehabilitation":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,56,87,116,145,174,201,232,276,299,321],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100649687","effect-of-surface-emg-biofeedback-on-quadriceps-inhibition-release-during-postoperative-knee-rehabilitation-100649687",false,"NCT07736625","Effect of Surface EMG Biofeedback on Quadriceps Inhibition Release During Postoperative Knee Rehabilitation","Effet du Biofeedback Par EMG de Surface Sur la levée d'Inhibition du Quadriceps en rééducation Post-opératoire du Genou","BIOQUAD","Inclusion Criteria:\n\n* AMI following knee surgery, as classified by the Santi classification system\n* Aged 18 or older\n* Enrolled in or covered by a social security program\n* Able to understand instructions and participate in standardized rehabilitation sessions\n\nExclusion Criteria:\n\n* Acute pain.\n* Neurological condition.\n* Skin lesion at the electrode site.\n* Allergy to the electrode.\n* Under legal protective measures such as guardianship or court-ordered protection","ALL","18 Years",{"count":20,"type":21},5,"ESTIMATED","INTERVENTIONAL",[24],"NA","Arthrogenic muscle inhibition (AMI) is a common neurological impairment following knee surgery that limits voluntary quadriceps activation and delays functional recovery. Persistent AMI may contribute to muscle weakness, altered gait, and poorer rehabilitation outcomes. Although several rehabilitation strategies have been proposed, no complementary intervention has consistently demonstrated strong evidence for improving AMI.\n\nThis prospective single-case experimental study aims to evaluate whether visual biofeedback based on surface electromyography (sEMG) improves quadriceps motor performance during standard rehabilitation. Each participant will complete eight standardized rehabilitation sessions, including four sessions with visual sEMG biofeedback and four sessions without visual feedback. The order of the two conditions will be randomized, allowing each participant to serve as his or her own control.\n\nThe primary objective is to determine whether visual sEMG biofeedback improves the accuracy of quadriceps contraction, assessed by the percentage deviation from a predefined target. Secondary objectives include evaluation of motor engagement, motor control, muscle activation, perceived exertion, and pain.\n\nBetween three and five adult patients presenting AMI after knee surgery will be included. Because recovery patterns are highly individualized, a Single-Case Experimental Design (SCED) with repeated within-subject measurements has been selected to characterize individual treatment responses while minimizing inter-individual variability",[27,28,29],"Arthrogenic Muscle Inhibition","Knee Injuries","Postoperative Rehabilitation",[31,32,33,34,35,36,27,37,38,39,40,41,42],"Surface Electromyography","Electromyography","EMG Biofeedback","Biofeedback","Quadriceps Muscle","Quadriceps Activation","Knee Rehabilitation","Knee Surgery","Motor Control","Neuromuscular Rehabilitation","Single-Case Experimental Design","SCED","NOT_YET_RECRUITING","2026-08-17",{"date":46,"type":47},"2026-08-19","ACTUAL",{"date":49,"type":21},"2026-08-01",{"date":51,"type":21},"2026-12-31",{"name":53,"class":54},"Hopitaux de Saint-Maurice","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":17,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":22,"phases":67,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":55},"100649967","paraspinal-nmes-and-spinopelvic-alignment-after-knee-arthroplasty-100649967","NCT07741162","Paraspinal NMES and Spinopelvic Alignment After Knee Arthroplasty","Effect of Paraspinal Neuromuscular Electrical Stimulation Added to Rehabilitation Program on Spinopelvic Alignment Parameters After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 40 and 80 years\n* Diagnosis of primary knee osteoarthritis scheduled for total knee arthroplasty\n* Radiographic evidence of Kellgren-Lawrence grade 3-4 knee osteoarthritis\n* Preoperative knee flexion contracture ≥ 5°\n* Measurable spinopelvic malalignment, defined as meeting at least one of the following criteria: pelvic tilt (PT) \\> 20°, sagittal vertical axis (SVA) \\> 50 mm, or lumbar lordosis (LL) \\\u003C 40°\n* IIntact cognitive function based on clinical judgment, sufficient to understand and follow verbal commands, cooperate with the rehabilitation program, and reliably comply with functional assessment procedures\n* Provision of written informed consent\n* Able to stand independently and undergo standing lateral radiography\n\nExclusion Criteria:\n\n* Prior lumbar or thoracic spinal surgery\n* History of hip arthroplasty\n* Prior knee arthroplasty (revision arthroplasty patients)\n* Active inflammatory arthritis (e.g., rheumatoid arthritis, psoriatic arthritis)\n* Neurological disease, including stroke, Parkinson's disease, peripheral neuropathy, or spinal cord pathology\n* Contraindications to NMES, including active cardiac pacemaker, implanted defibrillator, deep vein thrombosis, skin integrity impairment, malignancy, or epilepsy\n* Severe hip osteoarthritis or other lower extremity pathology significantly affecting spinopelvic alignment (e.g., leg length discrepancy, developmental hip dysplasia, contracture)\n* Inability to complete the standard rehabilitation protocol due to postoperative complications\n* Osteoporotic vertebral fracture or significant osteoporosis (T-score \\\u003C -2.5 at L1-L4)\n* Active treatment for malignancy\n* Psychiatric or medical condition that would prevent completion of the follow-up period\n* General contraindications to exercise","40 Years","80 Years",{"count":66,"type":21},80,[24],"Total knee arthroplasty (TKA) is a widely performed surgical procedure for patients with severe knee osteoarthritis. Following TKA, changes in lower extremity alignment and gait mechanics may influence the spinopelvic sagittal alignment, and postoperative rehabilitation programs traditionally focus on the knee joint without addressing the lumbopelvic chain.\n\nThis study aims to investigate whether adding paraspinal neuromuscular electrical stimulation (NMES) to a standard postoperative rehabilitation program (which includes quadriceps NMES) affects spinopelvic sagittal alignment parameters in patients undergoing TKA for primary knee osteoarthritis, compared with standard rehabilitation and quadriceps NMES alone.\n\nIn this single-center, prospective, randomized, single-blind (outcome assessor-blinded) controlled trial, eligible participants aged 40-80 years with primary knee osteoarthritis scheduled for TKA and with measurable spinopelvic malalignment will be randomly assigned in a 1:1 ratio to receive either standard rehabilitation with quadriceps NMES plus paraspinal NMES (intervention group) or standard rehabilitation with quadriceps NMES alone (control group) for 4 weeks (20 sessions).\n\nThe primary outcome is the change in radiographic spinopelvic parameters - including pelvic tilt, sacral slope, pelvic incidence, lumbar lordosis, sagittal vertical axis, and spinosacral angle - measured on standing lateral whole-spine radiographs at baseline (preoperative), before rehabilitation, after the 4-week intervention, and at 6-month follow-up. Secondary outcomes include knee and back pain (VAS), functional and quality-of-life measures (WOMAC, Knee Society Score, Forgotten Joint Score, Oswestry Disability Index, Nottingham Health Profile), performance-based tests (Timed Up and Go, 6-Minute Walk Test), and knee range of motion.\n\nThe investigators hypothesize that adding paraspinal NMES to standard rehabilitation will result in greater improvement in spinopelvic alignment parameters, and potentially in clinical\u002Ffunctional outcomes, compared with standard rehabilitation alone.",[70,29],"Knee Osteoarthritis",[72,73,74,75,76],"Total knee arthroplasty","Spinopelvic alignment","Neuromuscular electrical stimulation","Postoperative rehabilitation","Paraspinal muscles","2026-07-27",{"date":79,"type":47},"2026-08-03",{"date":81,"type":21},"2026-07-30",{"date":83,"type":21},"2027-07-30",{"name":85,"class":86},"Bursa Yuksek Ihtisas Training and Research Hospital","OTHER_GOV",{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":4,"eligibilityCriteria":93,"healthyVolunteers":11,"sex":17,"minAge":94,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":22,"phases":97,"briefSummary":98,"conditions":99,"keywords":104,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":55},"100643642","clinical-study-of-a-new-treatment-model-for-elderly-lung-cancer-patients-100643642","NCT07632664","Clinical Study of a New Treatment Model for Elderly Lung Cancer Patients","A Multicenter Clinical Study on a New Treatment Model Combining New Surgical Techniques, Perioperative Comprehensive Treatment, and Postoperative Rehabilitation for Elderly Patients With Lung Cancer","Inclusion Criteria:\n\n1. Aged ≥65 years old\n2. Pathologically confirmed non-small cell lung cancer with clinical stage eligible for curative surgical resection\n3. Complete preoperative geriatric comprehensive assessment data available\n4. Capable of finishing planned surgery and long-term follow-up\n5. Voluntarily sign informed consent form\n\nExclusion Criteria:\n\n1. History of other malignant tumors within recent 5 years\n2. Severe organic dysfunction of heart, liver, renal or respiratory system that cannot tolerate thoracic surgery\n3. Preoperative confirmed distant metastasis preventing radical resection\n4. Uncontrolled active severe infection or obvious coagulation disorders\n5. Severe psychiatric disorder or cognitive dysfunction failing to cooperate with treatment and follow-up\n6. Refuse random grouping and postoperative regular monitoring","65 Years",{"count":96,"type":21},1000,[24],"This multicenter prospective clinical study focuses on elderly patients with lung cancer. The investigators will build a standardized clinical registry database, develop perioperative risk stratification and surgical early-warning models, optimize individualized surgical regimens, construct multidisciplinary perioperative comprehensive therapy, integrated Chinese-Western medicine full-cycle management and personalized postoperative rehabilitation systems, so as to form a whole-process optimized treatment model for elderly lung cancer.",[100,101,102,29,103],"Lung Neoplasm","Thoracic Surgical Procedures","Perioperative Care","Aged",[105],"Elderly lung cancer, Risk stratification, Multimodality therapy, Integrated Chinese and Western Medicine, Enhanced recovery after surgery","RECRUITING","2026-07-14",{"date":109,"type":47},"2026-07-15",{"date":111,"type":47},"2024-08-01",{"date":113,"type":21},"2028-08-31",{"name":115,"class":54},"Peking University People's Hospital",{"id":117,"slug":118,"hasResults":11,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":122,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":94,"enrollmentInfo":124,"targetDuration":4,"studyType":22,"phases":126,"briefSummary":127,"conditions":128,"keywords":131,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":143,"locationsCount":4},"100642126","comparison-of-early-mobilization-and-electrical-stimulation-on-functional-recovery-after-lumbar-disc-herniation-surgery-100642126","NCT07575477","Comparison Of Early Mobilization And Electrical Stimulation On Functional Recovery After Lumbar Disc Herniation Surgery","Comparison Of Early Mobilization And Electrical Stimulation-Supported Rehabilitation On Functional Recovery, Pain Level, And Mobility After Lumbar Disc Herniation Surgery: A Prospective Randomized Controlled Trial","EMES-LDH","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Patients who have undergone primary lumbar disc herniation surgery\n* Being in the early postoperative period (within the first 2 weeks after surgery)\n* Clinically stable condition\n* Ability to understand and follow instructions\n* Willingness to participate in the study and provide informed consent\n\nExclusion Criteria:\n\n* History of previous spinal surgery\n* Presence of severe neurological deficits (e.g., progressive motor loss, cauda equina syndrome)\n* Contraindications to electrical stimulation (e.g., pacemaker, implanted electronic devices)\n* Presence of severe systemic or uncontrolled chronic diseases (e.g., severe cardiovascular, respiratory, or metabolic disorders)\n* Cognitive impairment or inability to cooperate with rehabilitation program Pregnancy",{"count":125,"type":21},60,[24],"This randomized controlled trial aims to compare the effectiveness of early mobilization alone versus early mobilization combined with electrical stimulation on functional recovery following lumbar disc herniation surgery. Lumbar disc herniation is a common cause of low back pain and functional limitation, significantly affecting quality of life.\n\nAlthough surgical intervention is effective in patients who do not respond to conservative treatment, optimal postoperative recovery largely depends on appropriate rehabilitation strategies. Early mobilization is widely recommended to prevent complications, preserve muscle function, and facilitate return to daily activities. In addition, electrical stimulation modalities such as neuromuscular electrical stimulation (NMES) and transcutaneous electrical nerve stimulation (TENS) have been increasingly integrated into rehabilitation programs to enhance pain control, muscle activation, and neuromuscular re-education.\n\nIn this study, a total of 60 participants who have undergone primary lumbar disc herniation surgery will be randomly assigned into two groups. The first group will receive an early mobilization program alone, while the second group will receive early mobilization combined with electrical stimulation (NMES\u002FTENS). The intervention period will last 6 to 8 weeks, with sessions conducted three times per week.\n\nPrimary outcomes include functional disability measured by the Oswestry Disability Index (ODI) and pain intensity measured by the Visual Analog Scale (VAS). Secondary outcomes include functional mobility assessed by the Timed Up and Go (TUG) test, walking speed assessed by the 10-Meter Walk Test (10MWT), and muscle strength evaluated using manual muscle testing (MMT).\n\nThe findings of this study are expected to contribute to the development of evidence-based postoperative rehabilitation protocols and to clarify the clinical effectiveness of electrical stimulation in patients undergoing lumbar disc herniation surgery",[129,130,29],"Lumbar Disc Herniation","Low Back Pain",[132,133,134,135,136],"Lumbar Surgery","Early Mobilization","Electrical Stimulation","Physiotherapy","Functional Recovery","2026-06-12",{"date":139,"type":47},"2026-06-16",{"date":141,"type":21},"2026-06-30",{"date":81,"type":21},{"name":144,"class":54},"Istanbul Medipol University Hospital",{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":152,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":153,"targetDuration":4,"studyType":22,"phases":155,"briefSummary":156,"conditions":157,"keywords":159,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":173},"100630832","accessible-remote-rehabilitation-system-for-real-time-biomechanical-monitoring-100630832","NCT07492797","Accessible Remote Rehabilitation System for Real-Time Biomechanical Monitoring","Development and Clinical Validation of an AI-Based Camera System for Real-Time Biomechanical Monitoring in Upper-Limb Rehabilitation","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Individuals undergoing or recovering from upper-limb or hand rehabilitation following musculoskeletal or neurological injury or surgery.\n* Ability to perform basic hand or upper-limb movement tasks required for the rehabilitation exercises.\n* Ability to understand study instructions and provide informed consent.\n\nExclusion Criteria:\n\n* Severe cognitive impairment preventing understanding of study procedures.\n* Medical conditions that prevent safe participation in hand or upper-limb rehabilitation exercises.\n* Severe visual impairment preventing interaction with the camera-based monitoring system.\n* Participation in another interventional study that could affect rehabilitation outcomes.",true,{"count":154,"type":21},40,[24],"This study evaluates a novel camera-based system designed to support remote rehabilitation by measuring hand and upper-limb biomechanics in real time. Many patients recovering from musculoskeletal or neurological conditions require frequent monitoring during rehabilitation, but regular clinic visits may be difficult due to distance, cost, or limited access to specialized care. Current telehealth approaches typically rely on qualitative assessments or self-reported feedback rather than objective biomechanical measurements.\n\nThe purpose of this study is to determine whether a computer vision-based system can accurately estimate biomechanical parameters such as joint angles, range of motion, muscle force, and joint torque using only a standard camera. The system analyzes hand movement using artificial intelligence and biomechanical modeling to provide real-time measurements during rehabilitation exercises.\n\nParticipants will perform guided hand-movement tasks while the system records video and extracts anatomical landmarks. These data will be used to compute biomechanical parameters and assess whether the system can reliably monitor rehabilitation progress remotely. The results will help determine whether this technology can provide clinicians with objective, continuous data to support personalized rehabilitation and improve patient outcomes.",[158,29],"Hand Injury Rehabilitation",[160,161,162,163],"Tele-rehabilitation","Computer Vision","Biomechanics","Hand Motion Analysis","2026-05-15",{"date":166,"type":47},"2026-05-19",{"date":168,"type":21},"2026-06-01",{"date":170,"type":21},"2027-03-14",{"name":172,"class":54},"Mississippi State University",2,{"id":175,"slug":176,"hasResults":11,"nctId":177,"briefTitle":178,"officialTitle":179,"acronym":4,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":17,"minAge":94,"maxAge":4,"enrollmentInfo":181,"targetDuration":4,"studyType":22,"phases":182,"briefSummary":183,"conditions":184,"keywords":187,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":4},"100635130","rehabilitation-interventions-after-cardiac-surgery-in-older-adults-100635130","NCT07548684","Rehabilitation Interventions After Cardiac Surgery in Older Adults","Rehabilitation Interventions After Cardiac Surgery in Older Adults: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥65 years\n* Undergoing cardiac surgery (e.g., coronary artery bypass grafting or valve surgery)\n* Conscious and able to cooperate\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Presence of neurological disorders (e.g., stroke, Parkinson's disease)\n* Lower extremity amputation or severe deformity\n* Impaired skin integrity in the application area\n* Contraindications to massage or kinesio taping\n* Refusal to participate",{"count":125,"type":21},[24],"This randomized controlled trial aims to investigate the effects of foot massage and kinesio taping on functional performance and kinesiophobia in older adults following cardiac surgery. Early mobilization after cardiac surgery is essential for improving recovery outcomes; however, pain, fear of movement (kinesiophobia), and reduced functional capacity may delay rehabilitation in older patients.\n\nParticipants aged 65 years and older who have undergone cardiac surgery will be randomly assigned to either a foot massage group or a kinesio taping group. The foot massage group will receive daily bilateral foot massage for seven consecutive days, while the kinesio taping group will receive standardized kinesio taping applications to the foot and ankle region during the same period.\n\nFunctional performance, kinesiophobia, pain intensity, cognitive status, and delirium will be assessed using validated outcome measures, including the Timed Up and Go test, Tampa Scale for Kinesiophobia, Visual Analog Scale, Standardized Mini-Mental Test, and Nursing Delirium Screening Scale. Assessments will be conducted preoperatively and on the seventh postoperative day.\n\nThe study aims to determine whether non-pharmacological, easily applicable interventions such as foot massage and kinesio taping can enhance functional recovery, reduce fear of movement, and support early mobilization in older adults after cardiac surgery.",[185,29,186],"Cardiac Surgery","Kinesiophobia",[188,189,185,190,191,186,29,133],"Foot Massage","Kinesio Taping","Older Adults","Functional Performance","2026-04-23",{"date":194,"type":47},"2026-04-24",{"date":196,"type":21},"2026-05-01",{"date":198,"type":21},"2027-02-01",{"name":200,"class":54},"University of Yalova",{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":207,"eligibilityCriteria":208,"healthyVolunteers":11,"sex":17,"minAge":63,"maxAge":209,"enrollmentInfo":210,"targetDuration":4,"studyType":212,"phases":4,"briefSummary":213,"conditions":214,"keywords":219,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":55},"100584253","pain-education-after-rotator-cuff-surgery-100584253","NCT06886932","Pain Education After Rotator Cuff Surgery","The Effect of Pain Neuroscience Education on Patients Undergoing Surgical Repair of Moderate-Sized Rotator Cuff Tears","PNE-RCS","Eligibility Criteria\n\nInclusion Criteria:\n\nDiagnosis of a medium-sized rotator cuff tear (1-3 cm) confirmed by Magnetic Resonance Imaging (MRI) and scheduled for surgical repair Age between 40 and 75 years Sufficient Turkish language proficiency to understand and complete the informed consent form and assessment scales Mini-Mental State Examination (MMSE) score ≥ 24, indicating adequate cognitive function for study participation\n\nExclusion Criteria:\n\nCorticosteroid injection received within the last 6 weeks Adhesive capsulitis, defined as loss of passive external rotation greater than 50% or 30° History of previous cervical, thoracic, or shoulder surgery Presence of cervical radiculopathy, characterized by pain and tingling radiating to the arm due to nerve root involvement Acromioclavicular joint pathology or shoulder instability causing shoulder pain Full-thickness rotator cuff tear Calcific tendinitis Systemic diseases (e.g., inflammatory arthritis, malignancy) or neurological disorders (e.g., fibromyalgia, other neurological deficits) Fracture, labral lesion, or biceps tendon injury in the affected shoulder Prior participation in a chronic pain psychological management program or presence of generalized body pain","75 Years",{"count":211,"type":21},45,"OBSERVATIONAL","Study Title: The Effect of Pain Neuroscience Education Combined with Conventional Rehabilitation on Pain Management and Functional Outcomes in Patients Undergoing Mini-Open Rotator Cuff Repair\n\nPurpose: This study aims to investigate whether adding Pain Neuroscience Education (PNE) to a conventional rehabilitation program improves pain management, physical function, and psychosocial outcomes in patients who have undergone mini-open surgery for rotator cuff tears (RCT). The study will also compare the effects of PNE when delivered before versus after surgery.\n\nWho Can Participate: Adults aged 40-75 who have been diagnosed with a medium-sized rotator cuff tear and are scheduled for mini-open surgical repair. Participants must meet specific health criteria and be willing to participate in the rehabilitation program.\n\nStudy Details:\n\nParticipants will be randomly assigned to one of three groups:\n\nGroup 1: Conventional rehabilitation only. Group 2: Conventional rehabilitation + PNE before surgery. Group 3: Conventional rehabilitation + PNE after surgery. PNE involves educational sessions that explain the biology of pain, how the nervous system processes pain, and strategies to reduce fear and catastrophizing related to pain.\n\nThe study will last approximately 12 weeks, with regular assessments of pain levels, physical function, and psychosocial factors (e.g., fear of movement, depression, sleep quality).\n\nPotential Benefits:\n\nParticipants may experience reduced pain, improved shoulder function, and better overall recovery.\n\nThe study may provide valuable insights into how PNE can enhance rehabilitation outcomes for patients with rotator cuff tears.\n\nPotential Risks:\n\nSome participants may find the educational sessions time-consuming or mentally challenging.\n\nThere is a small risk of discomfort during physical assessments or rehabilitation exercises.\n\nWhy is this study important?:\n\nRotator cuff tears are a common cause of shoulder pain and disability, especially in older adults. Post-surgical pain and fear of movement can slow recovery and reduce quality of life. This study will help determine whether PNE, when combined with conventional rehabilitation, can improve recovery outcomes and provide a better understanding of how timing (before or after surgery) affects its effectiveness.",[215,216,217,218,29],"Rotator Cuff Tears","Postoperative Pain Management","Shoulder Dysfunction","Kinesiophobia (Fear of Movement)",[220,29,221,186,222,216],"Pain Neuroscience Education","Rotator Cuff Tear","Shoulder Surgery Outcomes","2026-04-18",{"date":225,"type":47},"2026-04-22",{"date":227,"type":47},"2025-04-01",{"date":229,"type":21},"2026-09-30",{"name":231,"class":54},"Elif Dilara Durmaz",{"id":233,"slug":234,"hasResults":11,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":238,"eligibilityCriteria":239,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":240,"targetDuration":4,"studyType":212,"phases":4,"briefSummary":241,"conditions":242,"keywords":261,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":267,"lastUpdatePostDateStruct":268,"startDateStruct":270,"completionDateStruct":272,"leadSponsor":274,"locationsCount":55},"100633082","early-functional-response-as-a-predictor-of-clinical-outcomes-in-hand-rehabilitation-a-prospective-feasibility-study-using-a-digital-monitoring-system-100633082","NCT07522060","Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System","Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Clinician-Developed Digital Monitoring System","HANDREHPREDICT","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Hand or upper extremity pathology requiring rehabilitation, including but not limited to: flexor or extensor tendon injuries, peripheral nerve injuries or compression syndromes (including carpal tunnel syndrome, cubital tunnel syndrome), distal radius fractures, metacarpal or phalangeal fractures, joint injuries and instabilities, arthropathy (osteoarthritis, rheumatoid arthritis), trapeziometacarpal osteoarthritis, trigger finger, Dupuytren's disease, DeQuervain tenosynovitis, lateral epicondylitis and post-surgical upper extremity conditions\n* Under clinical responsibility of the principal investigator at the Faculty of Physical Therapy and Rehabilitation, Hacettepe University\n* Expected to attend minimum 8 rehabilitation sessions\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* • Active psychiatric illness precluding participation or completion of assessment tools\n\n  * Severe cognitive impairment precluding understanding of patient-reported outcome measures\n  * Literacy difficulties preventing self-completion of questionnaires\n  * Concurrent enrollment in another interventional clinical study\n  * Refusal to provide written informed consent",{"count":125,"type":21},"This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later. In rehabilitation practice, clinicians make numerous decisions each session regarding exercise type, frequency, duration, and treatment approach. Most of these decisions are currently made without systematic longitudinal data. This study addresses three fundamental questions using data collected during routine clinical care: (1) Can the rate of improvement in the first weeks of treatment predict functional status months later, across both session-based and milestone-based time points? (2) Are there meaningfully different recovery profiles among hand rehabilitation patients? (3) Is there measurable variation in clinical decision-making among patients with similar profiles, and does this variation relate to outcomes? A digital patient monitoring platform developed by the principal investigator, a physiotherapist and academic researcher specializing in hand rehabilitation serves as the data collection infrastructure. The platform records standard clinical assessment measures in a structured format and has been in active clinical use at Hacettepe University prior to this study. For research purposes, the system has been expanded to include structured capture of patient-reported outcomes, patient global impression of change, treatment protocol coding, home exercise adherence, and automated calculation of early response metrics.\n\nThis is a 12-month prospective observational cohort study enrolling a minimum of 60 patients. Data are stored securely on the university's institutional network. Patients are anonymized using identification codes. The study is subject to Hacettepe University Ethics Committee approval and participant informed consent. Findings are expected to generate evidence supporting data-driven clinical decision-making in rehabilitation and to provide a feasibility foundation for a larger multi-center study.",[243,244,245,246,247,248,249,250,251,252,253,254,255,256,257,258,259,260,29],"Hand","Hand Therapy","Upper Extremity","Prediction Models","Hand Injuries","Hand Injuries and Disorders","Hand Arthritis","Tendon Injuries","Wrist Fractures","Carpal Tunnel Syndrome (CTS)","Peripheral Nerve Injuries","Upper Extremity Injuries","Wrist Injuries","Finger Injuries","Trigger Finger","Trapeziometacarpal (TMC) Arthrosis","DeQuervain's Tenosynovitis","Cubital Tunnel Syndrome",[262,263,264,265,266],"digital health monitoring","real-world evidence","clinical decision support","upper extremity rehabilitation","early response prediction","2026-04-03",{"date":269,"type":47},"2026-04-13",{"date":271,"type":21},"2026-06-15",{"date":273,"type":21},"2027-06-01",{"name":275,"class":54},"Hacettepe University",{"id":277,"slug":278,"hasResults":11,"nctId":279,"briefTitle":280,"officialTitle":281,"acronym":4,"eligibilityCriteria":282,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":94,"enrollmentInfo":283,"targetDuration":4,"studyType":22,"phases":285,"briefSummary":286,"conditions":287,"keywords":4,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":290,"lastUpdatePostDateStruct":291,"startDateStruct":293,"completionDateStruct":295,"leadSponsor":297,"locationsCount":55},"100622377","effectiveness-of-a-visual-feedback-exercise-program-following-lumbar-surgery-100622377","NCT07382830","Effectiveness of a Visual Feedback Exercise Program Following Lumbar Surgery","Efficacy of Laser Pointer-Guided Visual Feedback Stabilization Exercise Program After Lumbar Microdiscectomy Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* To be between 18 and 65 years of age\n* Patients who underwent lumbar microdiscectomy surgery\n* Individuals who are literate in Turkish\n\nExclusion Criteria:\n\n* Patients who have previously undergone lumbar disc herniation surgery\n* The surgical procedure involving fusion has been performed.\n* Having a body mass index above 30\n* Suspected or confirmed tumors in the lumbar spine and spinal canal\n* Severe heart failure and cerebrovascular accident\n* The presence of cauda equina syndrome and concomitant diseases of the lumbar spine\n* The presence of heart conditions, orthopedic contraindications, or systemic diseases that could prevent participation in the exercise program\n* Refusing to participate in the study",{"count":284,"type":21},42,[24],"The aim of this study is to compare the effectiveness of stabilization exercises performed with visual feedback guided by a laser pointer after lumbar microdiscectomy surgery with that of standard stabilization exercises. The study, planned as a randomized controlled trial, will include 42 individuals aged 18-65 who have undergone lumbar microdiscectomy. Participants will be divided into two groups: a control group and a laser-guided exercise group. Both groups will undergo supervised stabilization exercises 3 days a week for 8 weeks, starting from the 6th postoperative week. The outcome measures were defined as pain, disability, back awareness, trunk muscle endurance, reaction time, balance, function, and lumbar proprioception. The findings are expected to demonstrate the effectiveness of visual feedback-assisted stabilization exercises in postoperative rehabilitation and contribute to clinical practice.",[288,29,289],"Lumbar Microdiscectomy","Randomized Controlled Trial","2026-01-25",{"date":292,"type":47},"2026-02-03",{"date":294,"type":47},"2026-01-16",{"date":296,"type":21},"2028-06-30",{"name":298,"class":54},"Suleyman Demirel University",{"id":300,"slug":301,"hasResults":11,"nctId":302,"briefTitle":303,"officialTitle":304,"acronym":4,"eligibilityCriteria":305,"healthyVolunteers":11,"sex":17,"minAge":306,"maxAge":94,"enrollmentInfo":307,"targetDuration":4,"studyType":22,"phases":309,"briefSummary":310,"conditions":311,"keywords":4,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":315,"completionDateStruct":317,"leadSponsor":319,"locationsCount":55},"100605339","the-influence-of-the-timing-of-postoperative-rehabilitation-intervention-on-the-clinical-efficacy-of-unilateral-biportal-endoscopic-spine-system-in-the-treatment-of-lumbar-disc-herniation-100605339","NCT07161232","The Influence of the Timing of Postoperative Rehabilitation Intervention on the Clinical Efficacy of Unilateral Biportal Endoscopic Spine System in the Treatment of Lumbar Disc Herniation","The Influence of the Timing of Postoperative Rehabilitation Intervention on the Clinical","Inclusion Criteria:\n\n* Aged between 19 and 65 years.\n\nDiagnosed with lumbar disc herniation by imaging and scheduled for unilateral biportal endoscopic (UBE) surgery.\n\nPresenting with radicular pain in the lower extremity, with a history of less than 1 year.\n\nAble to understand Chinese and complete questionnaires independently.\n\nPhysically capable of participating in exercise rehabilitation.\n\nWilling to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Aged under 18 or over 65 years.\n\nCombined with other spinal pathologies (e.g., ankylosing spondylitis, rheumatoid arthritis, spinal tumor, spinal fracture, cauda equina syndrome).\n\nDiagnosis of neurological disorders (e.g., multiple sclerosis, Parkinson's disease).\n\nPresence of uncontrolled cardiovascular, respiratory, or peripheral vascular diseases.\n\nHistory of severe psychiatric disorders (e.g., schizophrenia).\n\nPrevious history of spinal surgery.\n\nPregnancy or lactation.\n\nInability to understand or comply with the study procedures.","19 Years",{"count":308,"type":21},72,[24],"This study focuses on the impact of the timing of postoperative rehabilitation intervention on the clinical efficacy of unilateral biportal endoscopic spine surgery in the treatment of lumbar disc herniation. The main objective is to explore this impact and provide high-quality evidence-based medical evidence for making reasonable clinical decisions.",[129,29],"2025-08-30",{"date":314,"type":47},"2025-09-08",{"date":316,"type":47},"2025-03-28",{"date":318,"type":21},"2027-03-28",{"name":320,"class":54},"Li Xiang",{"id":322,"slug":323,"hasResults":11,"nctId":324,"briefTitle":325,"officialTitle":326,"acronym":4,"eligibilityCriteria":327,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":328,"targetDuration":4,"studyType":22,"phases":330,"briefSummary":331,"conditions":332,"keywords":335,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":350,"locationsCount":55},"100599155","the-effect-of-balance-training-using-a-dynamometric-platform-in-patients-undergoing-total-knee-arthroplasty-100599155","NCT07080814","The Effect of Balance Training Using a Dynamometric Platform in Patients Undergoing Total Knee Arthroplasty","The Effect of Balance Training Using a Dynamometric Platform on Muscle Strength, Proprioception, Balance, and Gait in Patients Undergoing Total Knee Arthroplasty: A Single-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients who have undergone total knee arthroplasty within the past 2 years and are hospitalized at the Orthopedic Rehabilitation Clinic of Ankara Etlik City Hospital, Physical Therapy Hospital.\n* Able to fully bear weight on the operated lower extremity in the third postoperative week.\n* Willingness to participate and signing of the written informed consent form.\n\nExclusion Criteria:\n\n* Bilateral knee arthroplasty\n* Age under 18 years\n* Receiving treatment at a physical therapy unit within the first 2 weeks after knee arthroplasty\n* Presence of significant visual or hearing impairment, active infection\n* Clinically unstable condition\n* Presence of central nervous system lesions (e.g., stroke, multiple sclerosis)\n* Presence of malignancy\n* Presence of a fracture in the lower extremity\n* Presence of any condition that would prevent participation in the treatment\n* History of lumbar disc surgery\n* History of previous surgery in the lower extremity\n* Presence of advanced osteoarthritis in the non-operated lower extremity",{"count":329,"type":21},46,[24],"Total knee arthroplasty (TKA) is a common surgery used to treat advanced knee osteoarthritis, especially when other treatments no longer help. While the surgery often reduces pain and improves joint alignment, many patients still have problems with balance and movement afterward.\n\nThis study will explore whether adding balance training using the Tecnobody ProKin system to standard physical therapy helps patients recover better after TKA. The researchers will measure balance, walking ability, leg strength, and body awareness (also called proprioception) using special equipment.\n\nThe main goal is to test the hypothesis that technology-supported balance training improves recovery outcomes more effectively than standard rehabilitation alone.",[70,333,29,334],"Total Knee Arthroplasty Recovery","Balance Training",[336,337,338,339,340,341,342],"Total Knee Arthroplasty","Muscle Strength","Proprioception","Gait","balance training","Static Balance","Dynamic Balance","2025-07-20",{"date":345,"type":47},"2025-07-23",{"date":347,"type":47},"2025-05-01",{"date":349,"type":21},"2027-05-01",{"name":351,"class":86},"Ankara Etlik City Hospital"]