[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pregnancy-of-unknown-location-pul\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pregnancy-of-unknown-location-pul":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100632920","expediting-pregnancy-of-unknown-location-risk-stratification-using-the-rom-plus-point-of-care-test-100632920",false,"NCT07519954","Expediting Pregnancy of Unknown Location Risk Stratification Using the ROM-Plus Point of Care Test","Inclusion Criteria:\n\n* PUL diagnosis in the UC Davis Emergency Department or Obstetrics and Gynecology Office\n* Vaginal bleeding\n* Clinically stable\n* English-speaking",true,"FEMALE","15 Years",{"count":19,"type":20},122,"ESTIMATED","OBSERVATIONAL","The goal of this study is to learn if the ROM-Plus bedside test can effectively triage patients who present with pregnancy of unknown location (PUL) and vaginal bleeding as high or low risk for ectopic pregnancy. The main question to answer is:\n\nCan the ROM-Plus bedside test effectively risk-stratify patients who present with PUL and vaginal bleeding as high or low risk for ectopic pregnancy after a single clinical encounter.\n\nParticipants will have a vaginal swab collected at the time of presentation.",[24],"Pregnancy of Unknown Location (PUL)",[26,27,28,29,30],"pregnancy of unknown location (PUL)","risk-stratification","ROM-Plus test","ectopic pregnancy","vaginal bleeding","NOT_YET_RECRUITING","2026-08-15",{"date":34,"type":35},"2026-08-18","ACTUAL",{"date":37,"type":20},"2026-10-01",{"date":39,"type":20},"2028-10",{"name":41,"class":42},"University of California, Davis","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":15,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100577743","mira-connect-study-100577743","NCT06802263","MIRA CONNECT Study","Assessing Accuracy and Precision of Home Quantitative Urine Beta hCG With Serum for Pregnancy of Unknown Location (CONNECT)","CONNECT","Inclusion Criteria for controls:\n\n* Non-pregnant\n\nInclusion Criteria for cases:\n\n* Diagnosed with PUL requiring ongoing surveillance of serum hCG levels\n\nExclusion Criteria for controls:\n\n* History of renal disease\n* History of type I or type II diabetes\n* Known malignancy of any diagnosis including hCG-secreting tumors (hepatobiliary tumors and neuroendocrine tumors) and ovarian germ cell tumors.\n* Gestational Trophoblastic Disease\n* Use of hormonal contraception within last 3 months\n* Patients who work the night shift\n\nExclusion Criteria for cases:\n\n* History of renal disease\n* History of type I or type II diabetes\n* Known malignancy of any diagnosis including hCG-secreting tumors (hepatobiliary tumors and neuroendocrine tumors) and ovarian germ cell tumors.\n* Gestational Trophoblastic Disease\n* Unstable patient, concern for ruptured ectopic pregnancy\n* Initial serum hCG level \\> 100,000 mIU\u002Fml","18 Years","40 Years",{"count":54,"type":20},35,"INTERVENTIONAL",[57],"NA","The goal of this pilot study is to assess the accuracy and precision of an at-home quantitative urine beta hCG (b-hCG) test in the management of pregnancy of unknown location (PUL).",[24],[61,62,63],"pregnancy","unknown location","b-hCG","RECRUITING","2025-09-12",{"date":67,"type":35},"2025-09-16",{"date":69,"type":35},"2024-06-01",{"date":71,"type":20},"2027-09-30",{"name":73,"class":42},"University of Colorado, Denver",1]