[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pressure-pain-threshold\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pressure-pain-threshold":75},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,58,91],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":35,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":57},"100646230","core-stability-vs-scapular-stabilization-on-hand-grip-strength-in-chronic-myofascial-neck-pain-100646230",false,"NCT07692126","Core Stability vs Scapular Stabilization on Hand Grip Strength in Chronic Myofascial Neck Pain","Core Stability Exercises Versus Scapular Stabilization Exercises on Hand Grip Strength in Patients With Chronic Myofascial Neck Pain","Inclusion Criteria:\n\n1. Patients diagnosed with chronic myofascial neck pain depending on referral, and physical examination.\n2. Sixty patients diagnosed with chronic myofascial neck pain for more than six months.\n3. Patients age range will 25-45 years\n4. Patients body mass index (BMI) will be 18.5-24.9 kg\u002Fm2\n5. Each patient suffering from all active MTrPs in the upper trapezius muscle with painful\u002F tender nodule.\n6. Patients have a constant neck pain with positive jump sign when palpating the upper trapezius muscle.\n7. Patients have referred pain, and symptoms of ipsilateral hand muscle weakness.\n8. No history of undergoing physiotherapy modalities or corticosteroid injection therapies in the past six months before the study\n\nExclusion Criteria:\n\n1. Presence of signs of severe pathology such as malignancies, mainly of the cervical region.\n2. Fracture of the cervical spine.\n3. Cervical radiculopathy or myelopathy.\n4. Diabetes mellitus.\n5. Trauma, cognitive anomalies, and surgery around neck, shoulders, or hand.\n6. Fibromyalgia or vascular syndromes such as vertebral basilar insufficiency.\n7. Pregnancy.\n8. Having undergone physical therapy within the past three months before the study.\n9. Having corticosteroid injection therapies in the past 3 months before the study.","ALL","25 Years","45 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Chronic myofascial neck pain (CMNP) is a painful non-articular musculoskeletal neck syndrome that is a persistent and prevalent with a high incidence of recurrence rate range 30-93%.Management of myofascial trigger points were directed at its deactivation, and prevention of its recurrence. Based on mechanical kinetic chain, the upper extremity functions as a unique system of connected segments those collaborated in a harmony in order to perform daily life activities. Core stability exercises maximize motor pathways mechanoreceptors' activities, as well scapular stabilization exercises are generally recommended based on reported benefits in terms of chronic neck pain. The relationship between chronic myofascial neck pain, and hand disability is quite strong. From mechanical point of view, core stability exercises improve trunk stability in line to enhance upper extremity efficiency that facilitates hand, and pinch grasping. In addition, scapular stabilization exercises could improve both hand, and pinch grasp strength and dexterity. Therefore, this randomized clinical trial will be conducted in line to clarify the superiority of the therapeutic effects between core stability exercises, scapular stabilization exercises, and conventional physical therapy program on hand grip strength, pinch grip strength, neck pain intensity level, pain pressure threshold, and whole upper extremity functional level in patients with chronic myofascial neck pain.",[27,28,29,30,31,32,33,34],"Myofascial Neck Pain","Hand Grip Strength","Pressure Pain Threshold","Trigger Point in Trapezius Muscle","Core Muscle Weakness","Scapular Muscle Endurance","Disability of the Arm, Shoulder, and Hand Questionnaire","Neck Pain Musculoskeletal",[36,37,28,38,39,40,41,42,29,43,44],"Core Stability Exercise","Scapular Stabilization Exercises","Chronic Myofascial neck syndrome","Trigger Points","Upper Trapezius","Pinch Grip Strength","Hand Held Dynamometer","Pressure Algometer","Diability of the Arm, Shoulder, and Hand Questionnaire (Arabic version), (Arabic-Q-DASH)","RECRUITING","2026-07-08",{"date":48,"type":49},"2026-07-10","ACTUAL",{"date":51,"type":49},"2026-06-01",{"date":53,"type":21},"2027-06-30",{"name":55,"class":56},"Cairo University","OTHER",1,{"id":59,"slug":60,"hasResults":11,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":11,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":4,"studyType":69,"phases":4,"briefSummary":70,"conditions":71,"keywords":77,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":4},"100642999","investigation-of-pain-modulation-phenotypes-in-female-patients-with-fibromyalgia-100642999","NCT07640607","Investigation of Pain Modulation Phenotypes in Female Patients With Fibromyalgia","Inclusion Criteria:\n\n1. Having received a diagnosis of fibromyalgia according to the 2016 ACR diagnostic criteria\n2. Female patients aged 18-65\n3. Being literate\n4. Having signed the informed consent form upon agreeing to participate in the study\n\nExclusion Criteria:\n\n1. Being under 18 or over 65 years of age\n2. Having any condition that may lower the pain threshold or cause chronic pain (Rheumatoid Arthritis, Ankylosing Spondylitis, systemic inflammatory diseases, malignancies, etc.)\n3. Any neurological condition (stroke, traumatic brain injury, multiple sclerosis, Parkinson's disease, central nervous system malignancies…)\n4. Peripheral artery disease\n5. Severe cardiopulmonary insufficiency (stage 3-4)\n6. Uncontrolled systemic diseases such as hypertension and diabetes\n7. Presence of an active infection\n8. Pregnancy\n9. Presence of cognitive impairment, hearing loss, or communication difficulties that would prevent understanding of questionnaires and protocols","FEMALE","18 Years","65 Years",{"count":68,"type":21},82,"OBSERVATIONAL","Fibromyalgia is characterized by altered pain processing, including impaired descending pain inhibition and central sensitization. While both mechanisms have been independently associated with disease severity, their interrelationship remains unclear. This cross-sectional study aims to investigate whether central sensitization symptoms mediate the relationship between conditioned pain modulation and fibromyalgia impact.",[72,73,74,75,76],"Fibromyalgia (FM)","Quantitative Sensory Testing","Central Sensitization","PRESSURE PAIN THRESHOLD","Pain Perception",[78,79,80],"Fibromyalgia","Pain sensitization","Conditioned pain modulation","NOT_YET_RECRUITING","2026-07-06",{"date":84,"type":49},"2026-07-07",{"date":86,"type":21},"2026-07-01",{"date":88,"type":21},"2026-09-01",{"name":90,"class":56},"Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey",{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":4,"eligibilityCriteria":97,"healthyVolunteers":11,"sex":16,"minAge":98,"maxAge":4,"enrollmentInfo":99,"targetDuration":4,"studyType":22,"phases":101,"briefSummary":102,"conditions":103,"keywords":104,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":4},"100580353","do-emotions-affect-mechanical-pain-thresholds-in-individuals-with-chronic-pain-100580353","NCT06836193","Do Emotions Affect Mechanical Pain Thresholds in Individuals with Chronic Pain?","Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain","Inclusion criteria\n\n* Above 18 years of age\n* Fluent in Swedish\n* Persistent chronic pain with duration \\> 6 months Exclusion criteria\n* Known neurological disease","19 Years",{"count":100,"type":21},152,[24],"The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds in individuals with chronic pain.",[75],[29,105,106],"Pain","Emotion","2025-02-17",{"date":109,"type":49},"2025-02-20",{"date":111,"type":21},"2026-01-01",{"date":113,"type":21},"2027-12-31",{"name":115,"class":56},"Linnaeus University"]