[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"prevention-of-incisional-hernia-using-prophylactic-mesh\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:prevention-of-incisional-hernia-using-prophylactic-mesh":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":4},"100657175","synthetic-mesh-for-prevention-of-hernia-after-open-abdomen-closure-study-100657175",false,"NCT07835334","Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy","Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy (SHIELD Study)","SHIELD","Inclusion Criteria:\n\n* Patients older than 18 years.\n* Patients managed with an open abdomen approach.\n* Patients undergoing definitive fascial closure.\n\nExclusion Criteria:\n\n* Patients in whom definitive fascial closure cannot be achieved.\n* Inability to complete clinical follow-up or high likelihood of loss to follow-up (e.g., residence outside the catchment area, lack of outpatient follow-up, etc.)","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of this clinical trial is to evaluate whether placement of a synthetic prophylactic onlay mesh during definitive fascial closure can reduce the incidence of incisional hernia in adult patients managed with an open abdomen approach following emergency surgery.\n\nThe main questions it aims to answer are:\n\n* Does prophylactic mesh placement reduce the incidence of incisional hernia compared with fascial closure without mesh?\n* Does prophylactic mesh placement influence the occurrence of postoperative complications such as evisceration or surgical site infection?\n\nResearchers will compare patients undergoing definitive fascial closure with prophylactic mesh placement to those undergoing fascial closure without mesh in order to determine whether the mesh decreases the incidence of incisional hernia and associated complications.\n\nParticipants will:\n\n* Undergo standard open abdomen management followed by definitive fascial closure.\n* Be randomly assigned to one of the two study groups:\n\n  * Definitive fascial closure without prophylactic mesh.\n  * Definitive fascial closure with placement of a synthetic prophylactic onlay mesh.\n* Attend clinical follow-up visits in the general surgery outpatient clinic.\n* Undergo clinical evaluations at 1, 6, and 12 months after surgery, including physical examination and, if necessary, imaging studies to detect incisional hernia or postoperative complications.",[27,28,29,30,31],"Open Abdomen","Incisional Hernia","Definitive Fascial Closure","Emergency Abdominal Surgery","Prevention of Incisional Hernia Using Prophylactic Mesh",[33,34,35,36,37,38,39,40,41,42,43,44],"Open abdomen","Incisional hernia","Prophylactic mesh","Definitive fascial closure","Emergency surgery","Negative pressure wound therapy","NPWT","Damage control surgery","Abdominal wall","Onlay mesh","Surgical complications","Emergency abdominal surgery","NOT_YET_RECRUITING","2026-09-17",{"date":48,"type":49},"2026-09-22","ACTUAL",{"date":51,"type":21},"2026-09-01",{"date":53,"type":21},"2027-09-01",{"name":55,"class":56},"Hospital San Juan de Dios Tenerife","OTHER"]