[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"proprioceptive-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:proprioceptive-disorders":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,75,102],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100652660","manual-therapy-vs-multicomponent-exercise-in-cervicogenic-headache-100652660",false,"NCT07776093","Manual Therapy vs. Multicomponent Exercise in Cervicogenic Headache","Effects of Manual Therapy Versus Multicomponent Exercise on Sensorimotor Function, Suboccipital Muscle Thickness, and Central Sensitization in Cervicogenic Headache: A Double-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of cervicogenic headache by a specialist physician,\n* Aged between 18 and 45 years,\n* Ability to read and write (literate),\n* Provision of signed informed consent to participate in the study.\n\nExclusion Criteria:\n\n* History of head or neck surgery,\n* History of spinal surgery,\n* History of severe cardiac conditions or cardiac surgery that contraindicates exercise,\n* History of ongoing or past malignancy,\n* Diagnosis of psychiatric disorders,\n* Diagnosis of migraine,\n* Diagnosis of fibromyalgia,\n* Having received medical (except analgesics), physical therapy, or other interventions (e.g., alternative medicine, massage therapy) for cervicogenic headache within the last 6 months,\n* Engaging in regular exercise or attending an exercise facility within the last 6 months,\n* Experiencing headaches strictly associated with the menstrual period,\n* Investigator decision for exclusion based on ethical or clinical grounds,\n* Communication problems interfering with evaluation and treatment.","ALL","18 Years","45 Years",{"count":20,"type":21},32,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to compare the effects of manual therapy and a multicomponent exercise program on suboccipital muscle thickness, joint position sense, pain, central sensitization, balance, and kinesiophobia in patients diagnosed with cervicogenic headache.\n\nCervicogenic headache is a common secondary headache originating from dysfunction in the upper cervical spine. Dysfunction in the deep neck muscles, impaired neck joint awareness, and heightened pain sensitivity (central sensitization) are frequently observed in these patients. While both manual therapy and targeted exercise are used in physiotherapy practice, evidence regarding their direct comparative effects on suboccipital muscle morphology and somatosensory parameters remains limited.\n\nParticipants will be randomly assigned to one of two treatment groups for a duration of 4 weeks (12 sessions total):\n\n1. Manual Therapy Group: Receives joint mobilization, myofascial release, trigger point release, and suboccipital distraction targeting the cervical region.\n2. Multicomponent Exercise Group: Receives deep cervical flexor strengthening, cervical proprioception training, head-eye coordination training, and progressive balance exercises.\n\nThe main questions the study aims to answer are:\n\n* Do manual therapy and multicomponent exercise improve suboccipital muscle thickness and cervical joint position sense in patients with cervicogenic headache?\n* Is there a significant difference between manual therapy and multicomponent exercise in reducing pain intensity, central sensitization, disability, and fear of movement (kinesiophobia)? It is hypothesized that both intervention protocols will yield significant clinical improvements, with specific synergistic adaptations in muscle structure, somatosensory system processing, and pain-related fear.",[27,28,29],"Cervicogenic Headache","Proprioceptive Disorders","Neck Pain Musculoskeletal","NOT_YET_RECRUITING","2026-08-17",{"date":33,"type":34},"2026-08-20","ACTUAL",{"date":36,"type":21},"2026-09-01",{"date":38,"type":21},"2027-03-31",{"name":40,"class":41},"Pamukkale University","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":58,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100353441","balance-rehabilitation-with-modified-visual-input-in-patients-with-neuropathy-100353441","NCT03881930","Balance Rehabilitation With Modified Visual Input in Patients With Neuropathy","Balance REhabilitation With Modified Visual Input in Patients With acQuired Chronic Demyelinating Neuropathy and PROprioceptive Disorders","REQ-PRO","Inclusion Criteria:\n\n* Patients with chronic demyelinating acquired neuropathy\n* Age ≥ 18 years.\n* Patients able to walk 20 meters without human assistance at least indoors with or without technical assistance.\n* Patients with complaints such as discomfort, walking instability related to sensitivity disorders.\n* Patients being clinically stable for at least 2 months, regardless of ongoing treatments.\n* Patients who have provided consent.\n\nExclusion Criteria:\n\n* Patients unable to walk 20 metres without technical and human assistance indoors.\n* Patients with an ongoing hospitalization.\n* Patients already included and participating in another intervention study.\n* Patients with ongoing balance rehabilitation and continued during the REQ-PRO program in another rehabilitation centre or practice.\n* Patients with ongoing acute treatment (related to polyneuropathy) started less than 2 months ago or stopped less than 2 months ago.\n* Patients with scheduled surgery during the period of the patient's participation in the protocol, preventing the successful completion of the rehabilitation program and participation in assessments.\n* Patients with recent surgery, in particular lower limb prosthesis (less than 1 year old) or equipment contraindicated for planned exercises such as standing kneeling positions.\n* Patients with skin wounds on the foot that contraindicate rehabilitation.\n* Patients with balance disorders of vestibular origin or central neurological pathology.\n* Patients with a visual disability.\n* Patients with a hearing impairment that prevents the patient from hearing and understanding instructions during the rehabilitation program or assessments.\n* Patients with an inability to speak or understand the French language.\n* Patients with cognitive or language impairments that prevent understanding of the protocol.\n* Patients with a residence outside of the Paris Region (Ile de France).\n* Patients with a known pregnancy.\n* Patients not affiliated to a social security system (beneficiary or having a right), deprived of their right, under guardianship, curatorship, prisoner.",{"count":51,"type":21},40,[24],"This research focuses on the effects of rehabilitation on balance, in patients with acquired chronic demyelinating neuropathy. Rehabilitation will be performed with or without vision.\n\nIt is planned to include 40 subjects consulting for walking instability related to sensitivity disorders.\n\nThis multicenter study will take place in Paris's area. Each participant will benefit from 20 rehabilitation sessions with a Physical Therapist and 3 assessments.\n\nThanks to randomization, patient will be allocated in one of the 2 following groups:\n\n* Control group, Patients will benefit from balance rehabilitation with open eyes.\n* Experimental group, they will perform the same exercises while keeping their eyes closed or their vision will be obstructed by a mask or disturbed by moving luminous dots projected on the environment in darkness.",[55,56,28,57],"Neuropathy","Ataxia","Balance; Distorted",[59,60,28,61,62,63],"Peripheral neuropathy","Balance","Visual dependence","Rehabilitation","Physical Therapy","RECRUITING","2026-05-26",{"date":67,"type":34},"2026-05-27",{"date":69,"type":34},"2019-10-01",{"date":71,"type":21},"2027-11-01",{"name":73,"class":41},"Assistance Publique - Hôpitaux de Paris",1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":82,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":74},"100308663","use-of-sensory-substitution-to-improve-arm-control-after-stroke-100308663","NCT03298243","Use of Sensory Substitution to Improve Arm Control After Stroke","Augmenting Kinesthetic Feedback to Improve Hemiparetic Arm Control After Stroke","Inclusion Criteria:\n\n* stroke survivors who can perform our stabilization and grip modulation tasks and who\n* had a single ischemic or hemorrhagic stroke of the middle cerebral artery (MCA) in the chronic state of recovery (\\> 6 months post-stroke).\n* ability to give informed consent and be able to follow two-stage instructions.\n* mild-to-moderate motor impairment as assessed using the upper extremity (UE) portion of the Fugl-Meyer Motor Assessment (FM); i.e., UE-FM score between 28 and 50 (inclusive) out of a possible 66.\n* proprioceptive deficit at the elbow in the more involved (contralesional) arm.\n* preserved tactile sensation in either the ipsilesional arm and\u002For thigh.\n* a minimal active wrist extension of 5°.\n\nExclusion Criteria:\n\n* Inability of subjects to give informed consent or follow two-stage instructions.\n* subjects with a bleeding disorder.\n* subjects with fixed contractures or a history of tendon transfer in the involved limb.\n* subjects with a diagnosis of myasthenia gravis, amyotrophic lateral sclerosis or any disease that might interfere with neuromuscular function.\n* subjects who are currently using or under the influence of aminoglycoside antibiotics, curare-like agents, or other agents that may interfere with neuromuscular function.\n* subjects with a history of epilepsy.\n* history of other psychiatric co-morbidities (e.g. schizophrenia).\n* malignant or benign intra-axial neoplasms.\n* concurrent illness limiting the capacity to conform to study requirements.\n* Cardiac pacemaker, cardiac arrhythmia or history of significant cardiovascular or respiratory compromise.\n* subjects with profound atrophy or excessive weakness of muscles in the target area(s) of testing.\n* subjects with a systemic infection.","21 Years",{"count":84,"type":21},30,[24],"Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) to improve motor function. Participants will be tested in performing reaching movements as well as more functional tasks such as simulated drinking from a glass",[88,28],"Stroke",[90,91,92],"stroke","proprioception","sensory substitution","2025-09-24",{"date":95,"type":34},"2025-09-29",{"date":97,"type":34},"2023-07-17",{"date":99,"type":21},"2026-05-31",{"name":101,"class":41},"Marquette University",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":109,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":4},"100559626","does-the-degree-of-cervical-stenosis-affect-proprioception-100559626","NCT06566573","Does the Degree of Cervical Stenosis Affect Proprioception?","Does the Degree of Stenosis Affect Cervical Proprioception in Patients With Cervical Problems?","Inclusion Criteria:\n\n* Individuals aged 18 and over\n* Previously performed cervical MRI\n* Cases whose stenosis classification can be clearly determined on MRI\n\nExclusion Criteria:\n\n* Individuals who did not agree to participate in the study\n* Individuals undergoing cervical surgery\n* Those with pain that restricts cervical movement\n* Those diagnosed with vertigo\n* Those with sudden hearing loss\n* Having additional neurological disorders\n* Those with psychiatric and cognitive disorders that would prevent measurement in the study",true,{"count":111,"type":21},108,[24],"Neck pain is a common health problem that negatively affects the quality of life of individuals of different age groups and most people experience this problem at some point in their lives. With age, changes occur in the neuromuscular functions of the cervical region that are considered normal. These changes lead to many problems such as postural disorder, decreased stabilization, loss of normal joint motion, balance disorders and decreased cervical joint position sense. When the literature was examined, the situation was observed that cervical proprioception, which is defined as joint position sense, has not been sufficiently investigated. In particular, researchers have not found any literature on how proprioceptive sensation varies according to the degree of cervical stenosis. Therefore, this study will provide a direction for the treatment of cervical region problems. The data will be discussed with appropriate statistical methods and treatment recommendations will be presented according to the results obtained.",[28,115],"Stenosis","2024-08-20",{"date":118,"type":34},"2024-08-22",{"date":120,"type":21},"2024-09-15",{"date":122,"type":21},"2025-09-15",{"name":124,"class":41},"Izmir Democracy University"]