[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"prosthesis-and-implant-dentistry\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:prosthesis-and-implant-dentistry":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100651563","home-use-dual-light-antibacterial-photodynamic-therapy-for-peri-implant-mucositis-in-full-arch-implant-prostheses-100651563",false,"NCT07763431","Home-Use Dual-Light Antibacterial Photodynamic Therapy for Peri-Implant Mucositis in Full-Arch Implant Prostheses","Efficacy of Home-Use Dual-Light Antimicrobial Photodynamic Therapy as an Adjunct to Supportive Peri-Implant Care in Patients With Peri-Implant Mucositis Around Screw-Retained Full-Arch Implant-Supported Prostheses: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18 years or older who agree to participate and provide written informed consent.\n* Rehabilitated with a screw-retained full-arch implant-supported fixed prosthesis (All-on-4, All-on-6 or All-on-X) delivered at least 3 months before enrolment.\n* Diagnosed with peri-implant mucositis according to the 2017 World Workshop case definitions.\n* HbA1c below 7.0% and stable systemic health.\n* Non-smoker for at least the preceding 6 months.\n* Willing to attend all scheduled follow-up visits at 2 and 4 weeks and to comply with the home-use protocol.\n\nExclusion Criteria:\n\n* Disability or severe motor impairment limiting the ability to perform the oral hygiene procedures required by the study.\n* Long-term antibiotic therapy.\n* Immunodeficiency.\n* Long-term corticosteroid therapy.\n* History of organ transplantation.\n* Refusal to participate.","ALL","18 Years",{"count":19,"type":20},24,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to learn whether a home-use light device helps control gum inflammation around dental implants in adults who have a full set of fixed teeth attached to implants. This gum inflammation, called peri-implant mucositis, is common and reversible, but can lead to more serious problems if it is not controlled. The device is meant to be added to the usual professional cleaning and hygiene care, not to replace it.\n\nThe main questions it aims to answer are:\n\n* Does adding the home-use light device reduce gum bleeding around the implants more than the usual care alone?\n* Does it reduce the depth of the space around the implants and the amount of harmful bacteria?\n\nResearchers will compare adults who receive the usual professional care plus the home-use light device with adults who receive the usual professional care alone, to see if the device improves gum health.\n\nParticipants will:\n\n* Receive professional cleaning and personalized instructions on how to keep their implant teeth clean at the start of the study.\n* Be placed by chance into one of two groups: usual care plus the home-use light device, or usual care alone.\n* Use the light device at home each day for 4 weeks (if in the device group)\n* Visit the clinic at the start, after 2 weeks, and after 4 weeks for gum checkups and to have bacteria samples taken.",[26,27,28,29,30,31],"Peri Implant Mucositis","Dental Implant Rehabilitation","Prosthesis and Implant Dentistry","Implant Supported Prosthesis","Photodynamic Therapy (PDT)","Antimicrobial Photodynamic Therapy","NOT_YET_RECRUITING","2026-08-10",{"date":35,"type":36},"2026-08-13","ACTUAL",{"date":38,"type":20},"2026-09-10",{"date":40,"type":20},"2027-07-10",{"name":42,"class":43},"University of Medicine and Pharmacy at Ho Chi Minh City","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100617207","passive-fit-of-implant-supported-complete-arch-prostheses-using-digital-workflows-100617207","NCT07315620","Passive Fit of Implant-Supported Complete-Arch Prostheses Using Digital Workflows","Evaluation of Passive Fit in Implant-Supported Complete-Arch Prostheses Using Three Digital Workflows, Including an Automated AI-Assisted Protocol: A Randomized Clinical Trial","MFS03-Pdental","Inclusion Criteria:\n\n1. Adults aged 18 years or older.\n2. Patients indicated for fixed implant-supported full-arch rehabilitation in the maxilla or mandible.\n3. Presence of clinically stable, osteointegrated titanium implants suitable for prosthetic rehabilitation.\n4. Absence of clinical or radiographic signs of peri-implant disease.\n5. Ability to understand the study procedures and provide written informed consent.\n6. Willingness and ability to attend all required clinical visits and evaluations.\n\nExclusion Criteria:\n\n1. Presence of peri-implant mucositis or peri-implantitis at the time of evaluation.\n2. Implant mobility or implant positioning that prevents proper prosthetic rehabilitation.\n3. Uncontrolled systemic medical conditions that could interfere with study participation or prosthetic treatment.\n4. Cognitive, psychological, or medical conditions that limit the ability to comply with study procedures.\n5. Inability to complete the required clinical evaluations or follow the study protocol, as judged by the investigator.",{"count":53,"type":20},30,[23],"The goal of this clinical trial is to evaluate and compare three digital workflows for the fabrication of definitive implant-supported full-arch prostheses in adult patients requiring fixed implant rehabilitation.\n\nThe main questions it aims to answer are:\n\n* Does an automated AI-assisted digital workflow improve the passive fit of definitive full-arch implant-supported prostheses compared with manual and splint-guided alignment workflows?\n* Are there differences in marginal, geometric, mechanical, and radiographic passivity among the three digital workflows? Researchers will compare manual CBCT-STL alignment, splint-guided alignment, and automated AI-assisted CBCT-STL alignment to see if the degree of digital workflow automation affects the passive fit of definitive full-arch implant-supported prostheses.\n\nParticipants will:\n\n* Be adults (18 years and older) indicated for fixed implant-supported full-arch rehabilitation.\n* Receive a definitive, screw-retained, full-arch implant-supported prosthesis fabricated using one of the three assigned digital workflows.\n* Undergo standardized clinical and radiographic assessments at the time of definitive prosthesis placement to evaluate prosthesis passive fit.",[28],[58,59,60,61,62,63],"Implant-Supported Prosthesis","Full-Arch Rehabilitation","Passive Fit","Digital Workflow","Computer-Aided Design and Manufacturing (CAD\u002FCAM)","AI-Assisted Workflow","RECRUITING","2026-01-08",{"date":67,"type":36},"2026-01-09",{"date":69,"type":20},"2026-01-01",{"date":71,"type":20},"2027-03-01",{"name":73,"class":43},"Universidad Complutense de Madrid",1]