[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pulmonary-resistance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pulmonary-resistance":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,53,73,89],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":35,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100654838","assessment-of-total-pulmonary-resistance-spapco-between-sea-level-la-vs-high-altitude-ha-after-re-ascent-in-healthy-individuals-100654838",false,"NCT07804589","Assessment of Total Pulmonary Resistance sPAP\u002FCO Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals","Effect of a One-week Descent From 2850m to Sea Level and Re-ascent in Patients With Pulmonary Arterial Hypertension and Healthy Controls Permanently Living > 2600m on Pulmonary Hemodynamics, Exercise Capacity, Blood Oxygenation, Sleep Disordered Breathing and Further Outcomes","Inclusion Criteria:\n\n* Adults aged 18-80 years and of all genders\n* Permanent residence \\> 2600 m.\n* healthy: no self-perceived cardiopulmonary disease limiting daily activities\n* written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>80 years\n* Participants who cannot follow the study investigations\n* Participants permanently living \\\u003C 2600m.\n* Participants who traveled and stayed overnight at altitudes \\\u003C2000 m in the past 4 weeks.\n* any self-perceived cardiopulmonary disease limiting daily activities",true,"ALL","18 Years","80 Years",{"count":21,"type":22},14,"ESTIMATED","INTERVENTIONAL",[25],"NA","To study the effect of a re-ascent after a one-week stay at sea level (after prior descent from 2850m) to high altitude (Quito Ecuador: 2850m) on pulmonary resistance (sPAP\u002FCO) and other hemodynamic outcomes in healthy individuals, who live permanently \\>2600m.",[28,29,30,31,32,33,34],"High Altitude","Healthy","Healthy Adult","High Altitude Effects","Pulmonary Resistance","Hemodynamic Changes","Echocardiography",[36,28,37,38,34,39],"Hypoxia","Pulmonary resistance","Health","Hemodynamics","NOT_YET_RECRUITING","2026-08-31",{"date":43,"type":44},"2026-09-04","ACTUAL",{"date":46,"type":22},"2026-09-25",{"date":48,"type":22},"2026-12-31",{"name":50,"class":51},"Silvia Ulrich Somaini","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":14,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":69,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":72,"locationsCount":52},"100654762","assessment-of-total-pulmonary-resistance-spapco-between-sea-level-la-vs-high-altitude-ha-after-re-ascent-in-patients-with-pulmonary-arterial-hypertension-pah-100654762","NCT07804693","Assessment of Total Pulmonary Resistance sPAP\u002FCO Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAH","Inclusion Criteria:\n\n* Adult patients aged 18-80 years and of all genders\n* Permanent residence \\> 2600 m\n* Diagnosis of pulmonary arterial hypertension PAH (PAHHA-Group) according to guidelines\n* Patients are stable on therapy\n* NYHA (new york heart association) functional class I-III.\n* written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>80 years\n* unstable condition\n* Patients who cannot follow the study investigations\n* Patient permanently living \\\u003C 2600m.\n* Patients who traveled and stayed overnight at altitudes \\\u003C2000 m in the past 4 weeks.\n* Patients with moderate to severe concomitant lung disease (FEV1\\\u003C70% or forced vital capacity \\\u003C70%), severe parenchymal lung disease, severe smokers (\\>20 cigarettes\u002Fday)\n* Severely hypoxemic patients at Quito permanently having persistent SpO2 (oxygen saturation by pulseoximetry) \\\u003C80% on ambient air.\n* Patient with a non-corrected ventricular septum defect\n* Relevant concomitant other disease of the heart, kidney, liver, blood (anemia hemoglobin\\\u003C11 g\u002Fdl)",{"count":60,"type":22},20,[25],"To study the effect of a re-ascent after a one-week stay at sea level (after prior descent from 2850m) to high altitude (Quito Ecuador: 2850m) on pulmonary resistance (sPAP\u002FCO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently \\>2600m.",[64,65,28,34,32],"Pulmonary Arterial Hypertension (PAH)","Pulmonary Vascular Disease",[64,36,28,67,32,34,68],"Pulmonary Hypertension","hemodynamics",{"date":43,"type":44},{"date":46,"type":22},{"date":48,"type":22},{"name":50,"class":51},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":14,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":79,"targetDuration":4,"studyType":23,"phases":80,"briefSummary":81,"conditions":82,"keywords":83,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":85,"startDateStruct":86,"completionDateStruct":87,"leadSponsor":88,"locationsCount":52},"100654757","assessment-of-total-pulmonary-resistance-spapco-between-high-altitude-ha-vs-sea-level-la-in-healthy-individuals-h-100654757","NCT07804485","Assessment of Total Pulmonary Resistance sPAP\u002FCO Between High Altitude HA vs. Sea Level LA in Healthy Individuals H","Inclusion Criteria:\n\n* Adults aged 18-80 years and of all genders\n* Permanent residence \\> 2600 m\n* healthy: no self-perceived cardiopulmonary disease limiting daily activities\n* written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>80 years\n* People who cannot follow the study investigations\n* Participant permanently living \\\u003C 2600m.\n* Participant who traveled and stayed overnight at altitudes \\\u003C2000 m in the past 4 weeks.\n* any self-perceived cardiopulmonary disease limiting daily activities",{"count":21,"type":22},[25],"To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP\u002FCO) and other hemodynamic outcomes in healthy individuals, who live permanently \\>2600m.",[28,30,34,32,33,29],[36,84,38,34,37,39],"High altitude",{"date":43,"type":44},{"date":46,"type":22},{"date":48,"type":22},{"name":50,"class":51},{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":14,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":95,"targetDuration":4,"studyType":23,"phases":96,"briefSummary":97,"conditions":98,"keywords":99,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":101,"startDateStruct":102,"completionDateStruct":103,"leadSponsor":104,"locationsCount":52},"100654741","assessment-of-total-pulmonary-resistance-spapco-between-high-altitude-ha-vs-sea-level-la-in-patients-with-pulmonary-arterial-hypertension-pah-100654741","NCT07804524","Assessment of Total Pulmonary Resistance sPAP\u002FCO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH","Inclusion Criteria:\n\n* Adult patients aged 18-80 years and of all genders\n* Permanent residence \\> 2600 m\n* Diagnosis of pulmonary arterial hypertension PAH (PAHHA-Group) according to guidelines\n* Patients are stable on therapy\n* NYHA (new york heart association) functional class I-III\n* written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>80 years\n* unstable condition\n* Patients who cannot follow the study investigations\n* Patient permanently living \\\u003C 2600m.\n* Patients who traveled and stayed overnight at altitudes \\\u003C2000 m in the past 4 weeks.\n* Patients with moderate to severe concomitant lung disease (FEV1\\\u003C70% or forced vital capacity \\\u003C70%), severe parenchymal lung disease, severe smokers (\\>20 cigarettes\u002Fday)\n* Severely hypoxemic patients at 2850m permanently having persistent SpO2 (oxygen saturation by pulseoximetry) \\\u003C80% on ambient air.\n* Patient with a non-corrected ventricular septum defect\n* Relevant concomitant other disease of the heart, kidney, liver, blood (anemia hemoglobin\\\u003C11 g\u002Fdl)",{"count":60,"type":22},[25],"To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP\u002FCO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently \\>2600m.",[64,65,28,34,32,33],[64,36,28,67,32,100,34,68],"Pulmonary vascular disease",{"date":43,"type":44},{"date":46,"type":22},{"date":48,"type":22},{"name":50,"class":51}]