[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pulpotomies-primary-teeth\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pulpotomies-primary-teeth":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,72,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100649824","assessment-of-clinical-success-of-custom-made-versus-prefabricated-zirconia-crowns-in-pulpotomized-primary-molars-100649824",false,"NCT07738471","Assessment of Clinical Success of Custom-Made Versus Prefabricated Zirconia Crowns in Pulpotomized Primary Molars","Assessment of Clinical Success of Custom-Made Versus Prefabricated Zirconia Crowns in Pulpotomized Primary Molars: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Children aged 5-8 years.\n\n  * Primary molars with deep carious lesions extending to the middle third of the dentin as confirmed radiographically.\n  * Absence of root caries.\n  * Absence of periapical or inter-radicular radiolucency.\n  * Absence of internal or external root resorption.\n  * Teeth in the opposite arch are present and in normal occlusion.\n  * Willingness to participate and adhere to the follow-up appointments\n\nExclusion Criteria:\n\n* Children with systemic health issues.\n\n  * Children with periodontal diseases.\n  * Children exhibiting parafunctional habits.\n  * Uncooperative children (Frankl scale (score 1 and 2).","ALL","5 Years","8 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","Early childhood caries often results in extensive destruction of primary molars, requiring pulpotomy followed by full-coronal restoration to ensure long-term function and durability. Zirconia crowns have become a popular esthetic restorative option; however, limited evidence is available regarding the clinical performance of custom-made zirconia crowns compared with prefabricated zirconia crowns. This randomized controlled clinical trial aims to compare the clinical performance of custom-made and prefabricated zirconia crowns placed on pulpotomized primary molars. Clinical performance will be evaluated using standardized clinical and radiographic outcome measures over the follow-up period to determine whether custom-made zirconia crowns provide comparable or improved outcomes.",[27,28],"Primary Molar Tooth","Pulpotomies Primary Teeth",[30,31],"Zirconia Crown","Customer","NOT_YET_RECRUITING","2026-07-29",{"date":35,"type":36},"2026-07-31","ACTUAL",{"date":38,"type":21},"2026-11",{"date":40,"type":21},"2027-11",{"name":42,"class":43},"Cairo University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":18,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100605921","comparison-of-hyaluronic-acid-theracal-and-mineral-trioxide-aggregate-as-pulpotomy-agents-in-primary-molars-100605921","NCT07168811","Comparison of Hyaluronic Acid, TheraCal, and Mineral Trioxide Aggregate as Pulpotomy Agents in Primary Molars","Comparative Clinical and Radiographic Evaluation of Hyaluronic Acid, TheraCal, and Mineral Trioxide Aggregate as Pulpotomy Agents in Primary Molars: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Age 4-8 years,\n* Co-operative patient\n* At least one restorable mandibular second primary molars with deep carious lesions requiring pulpotomy.\n* Absence of gingival swelling or sinus tract.\n* Absence of spontaneous pain.\n* Absence of pain on percussion.\n* Controlled bleeding.\n* First treatment the tooth.\n* Possibility of restoring the tooth with a stainless steel crown.\n* No Radiographic evidence of changes associated with pulp degeneration, such as widening of PDL space, internal root resorption, external root resorption, inter-radicular or periapical bone destruction (radiolucency).\n\nExclusion Criteria:\n\n* Swelling, sinus tract, or fistula.\n* Spontaneous pain.\n* Necrotic pulp, pathological mobility.\n* Cases require for general anesthesia.\n* A history of repeated need for analgesics.\n* Patients with any systemic diseases.\n* Uncontrolled bleeding.\n* Selected deciduous teeth without a permanent successor","4 Years",{"count":53,"type":21},66,[24],"This randomized clinical trial aims to evaluation the clinical and radiographic outcomes of hyaluronic acid, TheraCal, and Mineral Trioxide Aggregate (MTA) when used as pulpotomy agents in primary molars.\n\nThe main question it aims to answer is:\n\nIn children with restorable mandibular second primary molars requiring pulpotomy, does the use of hyaluronic acid or TheraCal LC, compared to MTA, result in improved clinical and radiographic success rates over a 12-month follow-up period?",[28,57],"Pulp Disease, Dental",[59,60,61],"Hyaluronic Acid","TheraCal","MTA","2025-09-04",{"date":64,"type":36},"2025-09-11",{"date":66,"type":21},"2025-10-01",{"date":68,"type":21},"2026-11-01",{"name":70,"class":43},"Al-Azhar University",1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":16,"minAge":51,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":89,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":71},"100583083","clinical-and-radiographic-evaluation-of-potassium-nitrate-in-polycarboxylate-versus-mineral-trioxide-aggregate-in-vital-pulpotomy-in-primary-molars-100583083","NCT06871709","Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars","Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars: a Randomized Clinical Trial","❖ Inclusion Criteria:\n\n1. Children aged 4 to 7 years, in good general health.\n2. Children with vital, deeply carious primary molars.\n3. No history of spontaneous pain, pathological mobility, draining sinus tract, redness or swelling of the vestibule.\n4. Normal gingival and periodontal condition, with no sensitivity to vestibular palpation, and no pain on percussion test.\n5. No sign of radiolucency in periapical or furcation area.\n6. No widening of PDL space or loss of lamina dura continuity.\n7. No evidence of internal\u002Fexternal pathological root resorption.\n\nExclusion Criteria:\n\n1. Children with a physical disability or medical disability.\n2. Unrestorable molars.\n3. Uncooperative patient.\n4. Parent unable to attend Follow- up visits.\n5. Parents refuse to give written informed consent.\n6. If the access was opened and irreversible pulpitis was evident.",true,"7 Years",{"count":82,"type":21},50,[24],"The purpose of this RCT is to compare the clinical\u002Fradiographic outcomes of Potassium nitrate in polycarboxylate cement and MTA as pulpotomy biomaterials used for asymptomatic vital primary lower second molar and this will help to clinically evaluate the use of alternative material in vital pulpotomy in primary molars with deep carious cavities.\n\nEmphasis is set on avoiding total pupectomy and maintaining radicular pulp vitality therefore maintain the tooth in a viable condition till it's shedding and eruption of the permanent successor.",[86,87,57,28,88],"Vital Pulp Therapies","Pulpotomy","Pulp Therapy",[90,91,61,87,92,93,94,95,96],"Mineral Trioxide Aggregate","Potassium Nitrate","Vital Pulpotomy","Vital Pulp therapy","Primary Molars","pulp therapy","Pulp disease","2025-03-06",{"date":99,"type":36},"2025-03-12",{"date":101,"type":21},"2025-05-30",{"date":103,"type":21},"2026-12-30",{"name":42,"class":43},{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":18,"enrollmentInfo":113,"targetDuration":4,"studyType":22,"phases":115,"briefSummary":117,"conditions":118,"keywords":119,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":71},"100563089","phase-1-clinical-and-radiographic-evaluation-of-hyaluronic-acid-gengigel-teething-versus-mineral-trioxide-aggregate-angelus-as-pulpotomy-agent-in-vital-primary-molars-100563089","NCT06611631","Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary Molars","Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary Molars: A Randomized Clinical Trial","HA - MTA","Inclusion Criteria:\n\n* Patients:\n\nAged 4-8 years, in good general health and medically within normal.\n\nTeeth:\n\n* Restorable mandibular primary molars.\n* History of reversible pulpitis.\n\nPre-operative Radiographic criteria:\n\n* Absence of periapical or inter-radicular radiolucencies.\n* Absence of widening of periodontal ligaments (PDL) space.\n* Absence of internal or external root resorption.\n\nExclusion Criteria:\n\nPatients:\n\n* With systemic disorders.\n* Physical or mental disabilities.\n* Unable to attend follow- up visits.\n* Refusal of Participation.\n* Refusal to sign the informed consent.\n\nTeeth:\n\n* Previously accessed teeth.\n* Mobile mandibular primary molars.\n* Swelling in the vestibule or on palpation.\n* Pain on percussion",{"count":114,"type":21},34,[116],"PHASE1","The goal of this clinical trial is to Clinical and Radiographic Evaluation of Hyaluronic Acid (Gengigel Teething) Versus Mineral Trioxide Aggregate( Angelus) as Pulpotomy Agent in Vital Primary Molars.\n\nThe main question it aims to answer is:\n\nIs there a difference in the clinical or radiographic success when using Hyaluronic acid (Gengigel Teething, Ricerfarma , Italy) versus mineral trioxide aggregate (Angelus, Londrina ,Brazil) in pulpotomy of carious primary molars in children?",[28,57],[120,121,61,90],"hyaluronic acid","HA","2024-11-01",{"date":124,"type":36},"2024-11-04",{"date":126,"type":21},"2025-03",{"date":128,"type":21},"2026-04",{"name":42,"class":43}]