[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"refractive-error\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:refractive-error":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,46,79,114,143],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100648750","iol-power-formula-prediction-accuracy-at-the-extremes-of-axial-length-a-prospective-outcome-verification-study-100648750",false,"NCT07724795","IOL Power Formula Prediction Accuracy at the Extremes of Axial Length: A Prospective Outcome Verification Study","Clinical Outcomes of Formula-dependent IOL Power Selection at the Extremes of Axial Length: a Cross-sectional Outcome Verification of Seven ESCRS-hosted Formulas and the Ladas Super Formula 2.0 in Short (\u003C22.0 mm) and Long (>26.0 mm) Eyes Using Refractive, Biometric, and Tomographic Assessment","FORMULEX-OV","Inclusion Criteria:\n\n* \\- Participation in the retrospective IOL power formula comparison study at the extremes of axial length (pseudonymized study ID assigned; complete preoperative biometry and archived formula outputs for all eight formula pathways)\n* Cataract surgery with a spherical (non-toric) IOL of one of the three reference models (HOYA Vivinex XY1, HOYA Vivinex Impress XY1-EM, or Johnson \\& Johnson Tecnis 1-Piece DIB00) at the study center between January 2022 and December 2025\n* Preoperative axial length below 22.0 mm (short stratum) or above 26.0 mm (long stratum), measured on IOLMaster 700\n* Documented implanted IOL model and power available from the operative record\n* At least 3 months since cataract surgery at the time of the outcome visit\n* Written informed consent for the outcome visit, including linkage of newly acquired postoperative data with the previously collected, pseudonymized preoperative planning data\n\nExclusion Criteria:\n\n* \\- Interval ocular surgery on the study eye since the original cataract surgery that may affect refraction or IOL position (e.g., corneal refractive surgery, IOL exchange or repositioning, secondary IOL implantation, or any intraocular surgery). Uncomplicated YAG laser capsulotomy without IOL repositioning is not an exclusion criterion\n* Implanted IOL not matching one of the three reference platforms (e.g., toric, multifocal or EDOF IOL, a different monofocal platform, or a sulcus-fixated IOL)\n* Toric IOL implantation\n* Acute ocular pathology preventing reliable refraction or biometric measurement\n* Cognitive or physical limitations precluding standardized subjective manifest refraction\n* Documented intraoperative complication with confirmed or suspected IOL malpositioning (e.g., posterior capsule rupture with vitreous loss, zonular dialysis requiring a capsular tension ring, sulcus placement)\n* Withdrawal of informed consent\n\nNote: macular pathology is not an exclusion criterion; macular status is documented on OCT and analyzed as a covariate.","ALL",{"count":19,"type":20},200,"ESTIMATED","6 Months","OBSERVATIONAL","This single-center, prospective, cross-sectional study evaluates how accurately eight modern intraocular lens (IOL) power calculation formulas predicted the postoperative refractive result in eyes with extreme axial length after cataract surgery. Patients previously operated at the study center who had a very short (axial length \\\u003C 22.0 mm) or very long (\\> 26.0 mm) eye and received a spherical monofocal IOL are invited to a single, non-invasive outcome visit. At this visit, standardized manifest refraction, optical biometry, corneal tomography, slit-lamp examination and, in long eyes, macular OCT are performed. The measured postoperative spherical equivalent is compared with the residual refraction that each of the eight formulas had predicted for the actually implanted IOL power, separately in short and long eyes. The study aims to identify which formula predicts the postoperative outcome most accurately at the extremes of axial length, where formula choice is most consequential and least well studied.",[25,26],"Pseudophakia","Refractive Error",[28,29,30,31,32],"Intraocular lens power calculation","IOL formula","Axial length","Short eye","Long eye","NOT_YET_RECRUITING","2026-07-21",{"date":36,"type":37},"2026-07-24","ACTUAL",{"date":39,"type":20},"2026-08-01",{"date":41,"type":20},"2027-07-01",{"name":43,"class":44},"Vienna Hospital Association","OTHER_GOV",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":45},"100632315","comparison-of-presbyond-laser-blended-vision-and-conventional-monovision-lasik-in-individuals-with-presbyopia-a-randomized-clinical-study-100632315","NCT07512089","Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical Study","Inclusion Criteria:\n\n* Adults aged 40 to 55 years with presbyopia\n* Suitable candidates for LASIK surgery based on clinical evaluation\n* Stable refractive status for at least 1 year\n* Best corrected distance visual acuity within normal range\n* Willing and able to provide written informed consent\n* Willing to comply with study visits and follow-up\n\nExclusion Criteria:\n\n* Previous ocular surgery\n* Corneal disease or abnormal corneal condition that may affect safety\n* Significant ocular disease affecting visual function\n* Severe dry eye or other ocular surface disorders\n* Systemic disease that may affect study participation\n* Inability to tolerate monovision or anisometropia\n* Any condition that the investigator considers unsuitable for the study","40 Years","55 Years",{"count":55,"type":20},100,"INTERVENTIONAL",[58],"NA","The goal of this clinical trial is to learn if laser blended vision (LBV) works better than traditional monovision LASIK to correct presbyopia in adults aged 40 to 55 years. Presbyopia is an age-related condition that makes it hard to see things up close. The study will also evaluate the safety of both procedures.\n\nThe main questions it aims to answer are:\n\nDoes LBV improve distance, intermediate, and near vision at the same time after surgery? Is LBV as safe as traditional monovision LASIK?\n\nResearchers will compare laser blended vision to traditional monovision LASIK to see if LBV provides better overall vision after surgery.\n\nParticipants will:\n\nBe randomly assigned to receive either laser blended vision or traditional monovision LASIK Have standard eye examinations before surgery Undergo LASIK surgery using the assigned method Return for follow-up visits at 1 week, 1 month, 3 months, and 6 months after surgery Complete vision tests and questionnaires about visual quality and satisfaction",[61,26],"Presbyopia",[61,63,64,65,66,67],"LASIK","Laser Blended Vision","Monovision","Refractive Surgery","Randomized Clinical Trial","RECRUITING","2026-07-05",{"date":71,"type":37},"2026-07-07",{"date":73,"type":37},"2026-05-12",{"date":75,"type":20},"2028-06-30",{"name":77,"class":78},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":17,"minAge":87,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":90,"conditions":91,"keywords":96,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":45},"100646171","survey-of-sensory-impairment-indicators-among-adults-aged-65-years-and-older-in-xinxing-county-100646171","NCT07694505","Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing County","A Cross-Sectional Survey of Global Priority Sensory Impairment Indicators Among People Aged 65 Years and Older in Xinxing County","Inclusion Criteria:\n\n1. Aged 65 years or older.\n2. Voluntarily participates in the study and provides signed informed consent.\n\nExclusion Criteria:\n\n1. Unable to cooperate with study-related examinations, including because of disability, communication barriers, or other reasons.\n2. Has severe systemic disease that may affect study examinations or make participation potentially hazardous to health.\n3. Considered by the investigator to be unsuitable for participation in the study.",true,"65 Years",{"count":89,"type":20},2854,"This cross-sectional population-based survey will be conducted among residents aged 65 years and older in Xinxing County, Yunfu, Guangdong Province, China. The study will use standardized eye examinations, visual acuity and refractive assessment, anterior segment examination, hearing screening and questionnaires to estimate effective refractive error coverage, effective cataract surgical coverage, effective hearing technology coverage, common eye disease status, and dual sensory impairment among older adults. The findings are intended to provide evidence for primary-level eye and hearing health services.",[92,93,94,95,26],"Visual Impairment","Hearing Loss","Dual Sensory Impairment","Cataract",[97,98,99,100,101,102,103,104,105],"Effective refractive error coverage","Effective cataract surgical coverage","Effective hearing technology coverage","Older adults","Population-based survey","Cross-sectional study","SENSIIS","WHOears","Xinxing County","2026-07-02",{"date":108,"type":37},"2026-07-10",{"date":110,"type":20},"2026-07-06",{"date":112,"type":20},"2026-12-31",{"name":77,"class":78},{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":17,"minAge":122,"maxAge":4,"enrollmentInfo":123,"targetDuration":4,"studyType":56,"phases":125,"briefSummary":126,"conditions":127,"keywords":129,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":45},"100640257","community-based-eye-screening-with-structured-referral-tracking-for-preventing-avoidable-blindness-in-adults-in-rawalpindi-pakistan-100640257","NCT07611682","Community-Based Eye Screening With Structured Referral Tracking for Preventing Avoidable Blindness in Adults in Rawalpindi, Pakistan","Community-Based Eye Screening With a Structured Referral Tracking Intervention for the Prevention of Avoidable Blindness Among Adults in Rawalpindi District, Pakistan","SIGHT","Inclusion Criteria:\n\n* Adults aged 18 years or above\n* Individuals diagnosed with visual impairment or eye conditions requiring referral to a tertiary eye care facility\n* Permanent residents of Rawalpindi District, Pakistan\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Individuals already undergoing treatment for the identified eye condition\n* Individuals requiring emergency ophthalmic care\n* Severe systemic or physical illness limiting follow-up\n* Individuals unable to provide informed consent","18 Years",{"count":124,"type":20},500,[58],"This cluster randomized controlled trial aims to evaluate the effectiveness of a Structured Referral Tracking (SRT) intervention in improving referral completion among adults identified with avoidable blindness during community-based eye screening camps in Rawalpindi District, Pakistan. Ten community clusters will be randomized into intervention and control groups. Participants in the intervention group will receive structured referral counseling, weekly reminder calls or messages, and customized referral guidance for eight weeks, while the control group will receive standard referral procedures. The primary outcome is referral completion at a tertiary eye hospital within eight weeks after screening. Secondary outcomes include knowledge regarding avoidable blindness, treatment satisfaction, feasibility, acceptability, and barriers influencing referral completion.",[95,26,128],"Diabetic Retinopathy",[130,131,95,26,128,132,133],"Community Eye Screening","Avoidable Blindness","Referral System","Structured Referral Tracking","2026-06-02",{"date":136,"type":37},"2026-06-04",{"date":138,"type":20},"2026-06-01",{"date":140,"type":20},"2026-11-30",{"name":142,"class":78},"Health Services Academy, Islamabad, Pakistan",{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":4,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":17,"minAge":150,"maxAge":151,"enrollmentInfo":152,"targetDuration":4,"studyType":56,"phases":154,"briefSummary":155,"conditions":156,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":45},"100620232","an-evaluation-of-myopia-control-lenses-on-wearing-experience-in-myopic-children-100620232","NCT07354945","An Evaluation of Myopia Control Lenses on Wearing Experience in Myopic Children","An Evaluation of Visual Comfort, Adaptation and Overall Satisfaction in Myopic Children Using A.M.L. Series of Lenses","Inclusion Criteria:\n\n* Volunteer participant\n* Informed consent of parent\u002Fguardian and assent of participant\n* Age equal to or greater than 6 years and not older than 12 years at the time of signing informed consent and assent\n* Spherical equivalent refraction (SER) by cycloplegic autorefraction equal or less than -0.50 D and equal or greater than -4.75D with astigmatism not more than 2.00 D on both eye\n* Difference in SER (anisometropia) between two eyes should not exceed 1.50 D\n* Best corrected visual acuity (BCVA) better than or equal to +0.10 LogMAR in each eye\n* Be in good general health, based on the participant and the parent's\u002Fguardian's knowledge\n* Willingness and ability to participate in study and comply with all scheduled visits\n\nExclusion Criteria:\n\n* History of Atropine, Orthokeratology, or Red Light treatment\n* Strabismus by cover test at near or distance wearing correction\n* Amblyopia\n* Any ocular or systemic condition known to affect refractive status (e.g. keratoconus, diabetes, Downs syndrome, or other developmental disorders, etc.)\n* Current use of ocular or systemic medications which, in the investigator's opinion, may significantly affect pupil size, accommodation or refractive state\n* History of ocular injury or surgery\n* Participation in any clinical study within 30 days of the Baseline visit\n* Study participants deemed inappropriate for the study by the investigator\n* The inherent ocular\u002Fsystemic discomfort (dry eyes, visual fatigue, headaches, etc.) that may affect the evaluation of the study lens wearing experience, from the investigator's perspective","6 Years","12 Years",{"count":153,"type":20},40,[58],"The goal of this research study is to understand the wearing experience of A.M.L. series of lenses in myopic children. The main questions it aims to answer are:\n\n* How quickly and effectively children adapt to the A.M.L. series of lenses?\n* The proportion of children who adapted to the A.M.L. series of lenses within 4 to 6 days?\n\n  40 myopic children aged 6 to 12 years will be recruited as participants, and all of them will be wearing A.M.L. series of lenses.\n\nParticipants will:\n\n* Wear A.M.L. series of lenses for a period of 2 weeks\n* Visit at day 4-6, week 1 and week 2.",[157,26],"Myopia","2026-01-22",{"date":160,"type":37},"2026-01-23",{"date":162,"type":37},"2026-01-02",{"date":164,"type":20},"2026-04-27",{"name":166,"class":167},"Essilor International","INDUSTRY"]