[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"renal-stone-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:renal-stone-disease":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100651965","long-term-safety-of-uas-assisted-vs-sheathless-rirs-in-non-prestented-patients-100651965",false,"NCT07767773","Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented Patients","Long-Term Safety Outcomes of Ureteral Access Sheath-Assisted Versus Sheathless Retrograde Intrarenal Surgery for Renal Stones ≤20 mm in Non-Prestented Patients: A Retrospective Comparative Cohort Study With Active Follow-up","Inclusion Criteria:\n\n* Age ≥18 years at time of index RIRS.\n* Primary RIRS performed at Al-Azhar University Hospitals between Jan 1, 2020 and Dec 31, 2025.\n* Renal stone(s) with maximum diameter ≤20 mm on preoperative imaging.\n* No ipsilateral ureteral stent or nephrostomy before index RIRS.\n* Documented operative record specifying whether a UAS was used.\n* At least 12 months elapsed since index RIRS.\n* Available contact information allowing invitation for active follow-up.\n\nExclusion Criteria:\n\n* Primary ureteral stone treated during the same procedure.\n* Staghorn or \\>20 mm stone burden.\n* Prior ipsilateral ureteral stricture or reconstructive surgery.\n* Congenital renal\u002Fureteral anomalies affecting outcome (e.g., horseshoe kidney, duplicated system).\n* Incomplete operative or preoperative imaging records that preclude determination of eligibility or exposure (UAS use).\n* Additional ipsilateral ureteral procedure during follow-up that independently causes ureteral narrowing.\n* Refusal to participate in active follow-up or failure to attend after repeated attempts.","ALL","18 Years",{"count":19,"type":20},1200,"ESTIMATED","OBSERVATIONAL","This retrospective comparative cohort study will include adult patients who underwent primary RIRS for renal stones ≤20 mm at Al-Azhar University Hospitals between January 2020 and December 2025. Patients will be classified by whether a ureteral access sheath (UAS) was used during the index RIRS, and all eligible patients will be invited for active long-term follow-up (minimum 12 months) to assess the composite outcome of delayed ipsilateral ureteral stricture or new\u002Fprogressive ipsilateral hydronephrosis and other safety and efficacy outcomes. Propensity-score methods and adjusted regression analyses will be used to control confounding.",[24,25,26,27,28,29],"Renal Stone Disease","Ureteral Stricture","Hydronephrosis","Urolithiasis","Retrograde Intrarenal Surgery","Ureteral Access Sheath","RECRUITING","2026-08-16",{"date":33,"type":34},"2026-08-18","ACTUAL",{"date":31,"type":34},{"date":37,"type":20},"2027-12-25",{"name":39,"class":40},"Al-Azhar University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":41},"100609207","the-larc-robot-simplifies-renal-access-in-percutaneous-nephrolithotomy-100609207","NCT07211555","The LARC Robot Simplifies Renal Access In Percutaneous Nephrolithotomy","The LARC Robot Simplifies Renal Access In Percutaneous Nephrolithotomy (PCNL)","Inclusion Criteria:\n\n* Kidney stones larger than 2 cm\n* Staghorn renal calculi\n* Lower pole stones less than 2 cm\n* Anatomical abnormalities that reduce the likelihood of spontaneous stone fragment passage, such as:\n* Horseshoe kidney\n* Calyceal diverticulum\n* Ectopic or dystopic kidney\n* Stones that are refractory to prior treatment (e.g., ESWL or ureteroscopy)\n* Suspected malignant tumors or masses located in the planned renal access tract\n\nExclusion Criteria:\n\n* Pregnancy\n* Active urinary tract infection (UTI) or untreated sepsis\n* Known bleeding disorders or uncorrectable coagulopathy despite medical management\n* Use of anticoagulant medications (e.g., warfarin, heparin, or DOACs) that cannot be safely discontinued\n* Allergy to contrast media that cannot be pre-medicated or managed\n* Severe cardiopulmonary comorbidities that contraindicate anesthesia or PCNL\n* Inability to provide informed consent\n* Participation in another investigational study that may interfere with study outcomes",{"count":50,"type":20},45,"INTERVENTIONAL",[53],"NA","This study is being done to evaluate a new robotic system that helps urologists more precisely reach the kidney during surgery to remove large kidney stones. The procedure, called percutaneous nephrolithotomy (PCNL), is typically used for people who have large or difficult-to-remove kidney stones.\n\nTraditionally, many urologists rely on radiologists to place a tube into the kidney before surgery. This can cause delays, require multiple procedures, and increase costs. The robotic system being studied - called LARC - is designed to help the urologist safely and accurately guide a needle directly into the kidney during the surgery, without needing a separate procedure beforehand.\n\nThe robot uses live X-ray images to help align the instruments. Although parts of the robot have been approved by the U.S. FDA, the version used in this study is still investigational and not yet approved for this specific purpose.\n\nThe study will take place at AdventHealth Celebration and include up to 45 adult patients who are scheduled for PCNL surgery. Participants will be followed for up to 1 month after surgery, and doctors will look at outcomes such as the success of the procedure, the number of kidney stones removed, complications, time in surgery, and radiation exposure.\n\nThis research may help make kidney stone surgery safer, faster, and more effective in the future.",[24,56,57,58],"Kidney Calculi","Refractory Kidney Stones","Kidney Stones",[60,61],"Robotic Surgery","Minimally Invasive Surgery","NOT_YET_RECRUITING","2025-09-30",{"date":65,"type":34},"2025-10-08",{"date":67,"type":20},"2025-11-01",{"date":69,"type":20},"2026-01-01",{"name":71,"class":40},"AdventHealth"]