[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"respiratory-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:respiratory-disorders":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,73,95],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100650234","effect-of-aerobic-and-resistance-exercise-on-quarry-workers-100650234",false,"NCT07744334","Effect of Aerobic and Resistance Exercise on Quarry Workers","Aerobic Versus Resistance Exercise Training on Ventilatory Function in Quarry Workers","AE RE VF","Inclusion Criteria:\n\n* Male quarry workers.\n* The age range is between 30 and 40 years.\n* BMI values from 25 to 29.9 kg\u002Fm².\n* They work 5 to 6 times per weeks with mean exposure range (5-10 years) (Kumar et al., 2014). Exhibited chest manifestations (Respiratory symptoms) like cough, dyspnea, wheeze, and ventilatory impairment with significant reduction in (FEV1\u002FFVC\\\u003C70% and\u002For FVC\\\u003C80% and reduce Peak Expiratory flow 25- 75% (PEF25-75%)(Abdelwahaab et al., 2025).\n* Clinically stable (no exacerbation in past 4-6 weeks).\n* Low levels of physical activity (using the International Physical Activity Questionnaire-Short Version) (The Arabic version of the questionnaire will be used).\n\nExclusion criteria:\n\n* Patients with acute respiratory infections or recent exacerbation(4-6 weeks).\n* Asthmatic patient.\n* Chest cancer.\n* Musculoskeletal diseases and other disorders that could potentially impact the study's findings are excluded from the trial.\n* Other major lung diseases (e.g., TB, ILD, bronchiectasis, cancer).\n* Unstable cardiovascular disease.\n* Uncontrolled hypertension.\n* Severe musculoskeletal or neurological limitation to exercise.\n* Cognitive impairment.\n* Participation in PR in past 6 months.\n* Heavy smokers.","MALE","30 Years","40 Years",{"count":21,"type":22},75,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this randomized clinical trial is to compare the effects of aerobic exercise training and resistance exercise training on ventilatory function in quarry workers. It will also evaluate their effects on functional capacity and health-related quality of life (HRQOL).\n\nThe main questions it aims to answer are:\n\nDoes aerobic exercise training improve ventilatory function more effectively than resistance exercise training? How do aerobic and resistance exercise training affect functional capacity and health-related quality of life in quarry workers?\n\nResearchers will compare aerobic exercise training and resistance exercise training with a control group receiving routine treatment and breathing exercises to determine which intervention is more effective in improving ventilatory function, functional capacity, and health-related quality of life.\n\nParticipants will:\n\nBe randomly assigned to one of three groups: an aerobic exercise training group, a resistance exercise training group, or a control group.\n\nReceive the assigned intervention three times per week for eight consecutive weeks.\n\nUndergo ventilatory function assessment using spirometry. Complete assessments of functional capacity and health-related quality of life before and after the intervention.",[28,29,30],"Ventilatory Defect","Occupational Lung Diseases","Respiratory Disorders","RECRUITING","2026-08-03",{"date":34,"type":35},"2026-08-05","ACTUAL",{"date":37,"type":35},"2026-07-09",{"date":39,"type":22},"2027-01-25",{"name":41,"class":42},"Cairo University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":60,"conditions":61,"keywords":62,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":43},"100230011","phase-1-use-of-hyperpolarized-xenon-gas-for-lung-imaging-in-children-and-adults-100230011","NCT02272049","Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults","Use of Hyperpolarized 129 Xe MR Lung Imaging in Children and Adults","HPXeMR","Inclusion Criteria:\n\n* Ages 6 and up\n* Participant must be able to hold breath for up to 16 seconds\n\nExclusion Criteria:\n\n* History of heart defect\n* Pregnancy or positive pregnancy test\n* History of uncontrolled asthma defined for this study as requiring use of rescue inhaler ≥ 2 times in past month\n* Symptoms of respiratory infection (loose or productive cough or wheeze), chest tightness, or sinus infection within past week\n* Baseline oximetry at MRI visit of less than 95% on room air or less than 95% on a previously prescribed dosage of oxygen delivered by nasal cannula\n* Participant is claustrophobic and unable to tolerate the imaging.\n* Standard MRI exclusions (metal, implants)",true,"ALL","6 Years",{"count":56,"type":22},300,[58,59],"PHASE1","PHASE2","The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of children and adults and in adults and also in children with respiratory compromise due to a variety of diseases.",[30],[63],"Respiratory","2026-02-12",{"date":66,"type":35},"2026-02-17",{"date":68,"type":35},"2014-12",{"date":70,"type":22},"2029-08-31",{"name":72,"class":42},"Children's Hospital Medical Center, Cincinnati",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":52,"sex":53,"minAge":80,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":23,"phases":83,"briefSummary":84,"conditions":85,"keywords":86,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":43},"100233413","phase-1-use-of-hyperpolarized-129xe-mr-lung-imaging-in-adults-for-calibration-100233413","NCT02316379","Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration","HpXeMRCal","Inclusion Criteria:\n\n* Adults ages 18 years and older\n* Participant must be able to hold their breath for up to 16 seconds\n\nExclusion Criteria:\n\n* History of heart defect\n* Pregnancy or positive pregnancy test\n* History of uncontrolled asthma defined for this study as requiring use of rescue inhaler ≥ 2 times in past month.\n* Symptoms of respiratory infection (loose or productive cough or wheeze), chest tightness, or sinus infection within past week.\n* Baseline oximetry at MRI visit of less than 95% on room air or less than 95% on a previously prescribed dosage of oxygen delivered by nasal cannula.\n* Participant is claustrophobic and unable to tolerate the imaging.\n* Standard MRI exclusions (metal, implants).","18 Years",{"count":82,"type":22},100,[58,59],"The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of adults for the purposes of obtaining optimal images through MRI.",[30],[63],"2025-09-03",{"date":89,"type":35},"2025-09-10",{"date":91,"type":4},"2015-02",{"date":93,"type":22},"2031-08-24",{"name":72,"class":42},{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":53,"minAge":103,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":23,"phases":106,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":43},"100589224","effects-of-pulmonary-rehabilitation-in-salt-chambers-on-functional-efficiency-respiratory-parameters-and-blood-rheology-in-elderly-with-respiratory-diseases-100589224","NCT06951633","Effects of Pulmonary Rehabilitation in Salt Chambers on Functional Efficiency, Respiratory Parameters, and Blood Rheology in Elderly With Respiratory Diseases.","Functional Efficiency, Respiratory Parameters and Blood Rheological Tests in Elderly People With Respiratory Diseases Participating in Pulmonary Rehabilitation in Underground Salt Chambers - a Prospective Experimental Study, Controlled in a Crossover Design","PRSC-FERPBR","Inclusion Criteria:\n\n* people aged 65 and older with chronic respiratory diseases in a stable period of the disease (without exacerbations), qualified to participate in a rehabilitation and treatment stay in the underground Health Resort 'Wieliczka' Salt Mine in Wieliczka,\n* patients who gave informed, written consent to participate in the study.\n\nExclusion Criteria:\n\n* patients with contraindications to subterraneotherapy and physical exercise,\n* lack of written consent to participate in the study,\n* deterioration of health during the implementation of the program.","65 Years",{"count":105,"type":22},33,[25],"The aim of the study is to assess the impact of the rehabilitation and treatment stay at the underground Health Resort of the 'Wieliczka' Salt Mine in Wieliczka on the functional capacity, respiratory parameters, and rheological properties of blood in elderly individuals with respiratory diseases.",[109,30],"the Elderly",[111],"Pulmonary function, speleotherapy, blood tests, 6MWT, chest","2025-04-22",{"date":114,"type":35},"2025-04-30",{"date":116,"type":35},"2025-04-04",{"date":118,"type":22},"2026-02-28",{"name":120,"class":42},"University School of Physical Education, Krakow, Poland"]