[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"retinal-thickening\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:retinal-thickening":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":40,"locationsCount":5},"100658867","retinal-and-choroidal-changes-in-periodontal-disease-100658867",false,"NCT07856901","Retinal and Choroidal Changes in Periodontal Disease","RETİNAL AND CHOROİDAL STRUCTURAL ALTERATİONS ACROSS THE PERİODONTAL DİSEASE CONTİNUUM: A CROSS-SECTİONAL OBSERVATİONAL STUDY","Inclusion Criteria:\n\nSystemically healthy adults. Non-smokers (no current or previous tobacco use). Participants who underwent optical coherence tomography (OCT) imaging. Participants who provided written informed consent and agreed to participate in the study.\n\nExclusion Criteria:\n\nPresence of any systemic disease. Current or former smokers. Participants with incomplete clinical or OCT data. Individuals who did not provide written informed consent.\n\n\\-",true,"ALL","20 Years","54 Years",{"count":21,"type":22},80,"ESTIMATED","1 Day","OBSERVATIONAL","Advanced PeriodontitisIn this cross-sectional study, the relationship between periodontal disease severity and retinal and choroidal structural changes was evaluated using SD-OCT. Data from a total of 80 participants were examined. It was found that choroidal thickness increased and ganglion cell layer thickness decreased as periodontal disease severity increased, while no significant relationship was found in RNFL and IPL thicknesses. The findings support a possible association between periodontal disease and ocular structural changes.",[27,28,29],"Periodontal Diseases","Periodontal Diseases Inflammation","Retinal Thickening",[31],"Retinal degeneration ; Tomography, Optical Coherence ; Periodontitis ; gingivitis; Retinal Ganglion Cells ; Periodontal Index","NOT_YET_RECRUITING","2026-09-28",{"date":35,"type":36},"2026-10-05","ACTUAL",{"date":38,"type":22},"2026-10",{"date":38,"type":22},{"name":41,"class":42},"Zeliha Başak Çakır Erdil","OTHER"]